Search Results - "Verschure, Derk O"
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Cardiac 123I-mIBG Imaging in Heart Failure
Published in Pharmaceuticals (Basel, Switzerland) (25-05-2022)“…Cardiac sympathetic upregulation is one of the neurohormonal compensation mechanisms that play an important role in the pathogenesis of chronic heart failure…”
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Cardiac sympathetic activity and lethal arrhythmic events: insight into bell-shaped relationship between 123I-meta-iodobenzylguanidine activity and event rates
Published in EJNMMI research (21-07-2024)“…Background 123 I- meta -iodobenzylguanidine ( m IBG) has been applied to patients with chronic heart failure (CHF). However, the relationship between 123 I -m…”
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A Novel 12-Lead Electrocardiographic System for Home Use: Development and Usability Testing
Published in JMIR mHealth and uHealth (30-07-2018)“…Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. Early diagnosis is of pivotal importance for patients with cardiac…”
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123I-MIBG heart-to-mediastinum ratio is influenced by high-energy photon penetration of collimator septa from liver and lung activity
Published in Nuclear medicine communications (01-03-2015)“…AIMThe I-metaiodobenzylguanidine (I-MIBG) late heart-to-mediastinum ratio (H/M) is a well-established prognostic parameter in patients with chronic heart…”
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Standardization of 123I-meta-iodobenzylguanidine myocardial sympathetic activity imaging: phantom calibration and clinical applications
Published in Clinical and translational imaging : reviews in nuclear medicine and molecular imaging (2017)“…Purpose Myocardial sympathetic imaging with 123 I- meta -iodobenzylguanidine ( 123 I- m IBG) has gained clinical momentum. Although the need for…”
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Impact of a predefined mediastinal ROI on inter-observer variability of planar 123I-MIBG heart-to-mediastinum ratio
Published in Journal of nuclear cardiology (01-06-2014)“…Purpose of this study was to assess the impact of mediastinal region of interest (ROI) definition on intra- and inter-observer variability in relation to…”
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Anthracycline-induced cardiotoxicity: Is there a role for myocardial 123I-mIBG scintigraphy?
Published in Journal of nuclear cardiology (01-06-2020)Get full text
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The role of myocardial innervation imaging in different clinical scenarios: an expert document of the European Association of Cardiovascular Imaging and Cardiovascular Committee of the European Association of Nuclear Medicine
Published in European heart journal cardiovascular imaging (28-04-2021)“…Abstract Cardiac sympathetic activity plays a key role in supporting cardiac function in both health and disease conditions, and nuclear cardiac imaging has…”
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Vascular time-activity variation in patients undergoing 123I-MIBG myocardial scintigraphy: implications for quantification of cardiac and mediastinal uptake
Published in European journal of nuclear medicine and molecular imaging (01-06-2011)“…Purpose For the quantification of cardiac 123 I-metaiodobenzylguanidine (MIBG) uptake, the mediastinum is commonly used as a reference region reflecting…”
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Role of cardiac 123I-mIBG imaging in predicting arrhythmic events in stable chronic heart failure patients with an ICD
Published in Journal of nuclear cardiology (01-08-2019)“…Despite therapeutic improvement, the prognosis of chronic heart failure (CHF) remains unfavorable partly due to arrhythmia and sudden cardiac death (SCD). This…”
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Comparison of Taiwanese and European Calibration Factors for Heart-to-Mediastinum Ratio in Multicenter 123I-mIBG Phantom Studies
Published in Annals of Nuclear Cardiology (2023)“…Background: Cross-calibration of 123I-labeled meta-iodobenzylguanidine (mIBG) myocardial-derived indices is essential to extrapolate findings from several…”
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Cardiac 123I-mIBG scintigraphy is associated with freedom of appropriate ICD therapy in stable chronic heart failure patients
Published in International journal of cardiology (01-12-2017)“…Chronic heart failure (CHF) is a life-threatening clinical syndrome, partly due to sudden cardiac death (SCD). Implantable cardioverter defibrillators (ICD)…”
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A European myocardial 123I-mIBG cross-calibration phantom study
Published in Journal of nuclear cardiology (01-08-2018)“…Planar myocardial 123I-meta-iodobenzylguanidine (123I-mIBG) scintigraphy is a highly reproducible technique. However, differences in collimator use are one of…”
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Myocardial 123I-mIBG scintigraphy in relation to markers of inflammation and long-term clinical outcome in patients with stable chronic heart failure
Published in Journal of nuclear cardiology (01-06-2018)“…Chronic heart failure (CHF) results in both increased cardiac sympathetic activity and myocardial inflammation. The aim of this study was to identify the…”
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Polymorphism of SLC6A2 gene does not influence outcome of myocardial 123I-mIBG scintigraphy in patients with chronic heart failure
Published in Journal of nuclear cardiology (01-06-2018)“…The NET, encoded by SLC6A2, is responsible for presynaptic NE-reuptake. 123I-mIBG is clinically used to evaluate cardiac sympathetic function. However, it is…”
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Tako-tsubo cardiomyopathy: how to understand possible pathophysiological mechanism and the role of (123)I-MIBG imaging
Published in Journal of nuclear cardiology (01-08-2014)“…Tako-tsubo cardiomyopathy (TCM) is an increasingly recognized clinical syndrome characterized by acute reversible apical ventricular dysfunction, commonly…”
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Corrigendum to “Cardiac sympathetic activity in 22q11.2 deletion syndrome” [Int. J. Cardiol. 212 (2016) 346–351]
Published in International journal of cardiology (01-11-2016)Get full text
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Cardiac sympathetic activity in 22q11.2 deletion syndrome
Published in International journal of cardiology (01-06-2016)“…Abstract Aim 22q11.2 Deletion syndrome (22q11.2DS) affects catechol- O -methyl-transferase (COMT), which involves the degradation of norepinephrine (NE)…”
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Tako-tsubo cardiomyopathy: How to understand possible pathophysiological mechanism and the role of 123I-MIBG imaging
Published in Journal of nuclear cardiology (01-08-2014)“…Tako-tsubo cardiomyopathy (TCM) is an increasingly recognized clinical syndrome characterized by acute reversible apical ventricular dysfunction, commonly…”
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Cardiac sympathetic activity in hypertrophic cardiomyopathy and Tako-tsubo cardiomyopathy
Published in Clinical and translational imaging : reviews in nuclear medicine and molecular imaging (2015)“…123 I- meta -iodobenzylguanidine ( 123 I- m IBG) scintigraphy has been established as an important technique to evaluate cardiac sympathetic function and it…”
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