Search Results - "Verschueren, Charlène"

Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions by Soriano-Baguet, Leticia, Grusdat, Melanie, Kurniawan, Henry, Benzarti, Mohaned, Binsfeld, Carole, Ewen, Anouk, Longworth, Joseph, Bonetti, Lynn, Guerra, Luana, Franchina, Davide G., Kobayashi, Takumi, Horkova, Veronika, Verschueren, Charlène, Helgueta, Sergio, Gérard, Deborah, More, Tushar H., Henne, Antonia, Dostert, Catherine, Farinelle, Sophie, Lesur, Antoine, Gérardy, Jean-Jacques, Jäger, Christian, Mittelbronn, Michel, Sinkkonen, Lasse, Hiller, Karsten, Meiser, Johannes, Brenner, Dirk

“…Pyruvate dehydrogenase (PDH) is the central enzyme connecting glycolysis and the tricarboxylic acid (TCA) cycle. The importance of PDH function in T helper 17…”
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FHR4‐based immunoconjugates direct complement‐dependent cytotoxicity and phagocytosis towards HER2‐positive cancer cells by Seguin‐Devaux, Carole, Plesseria, Jean‐Marc, Verschueren, Charlène, Masquelier, Cécile, Iserentant, Gilles, Fullana, Marie, Józsi, Mihály, Cohen, Jacques H. M., Dervillez, Xavier

“…Directing selective complement activation towards tumour cells is an attractive strategy to promote their elimination. In the present work, we have generated…”
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O4 Spatial distribution of HIV in antiretroviral-treated humanised mice by Virginie Fievez, Coralie Guerin, Jean-Marc Plesseria, Charlène Verschueren, Ward De Spiegelaere, Michel Moutschen, Linos Vandekerckhove, Carole Devaux

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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation by Bonetti, Lynn, Horkova, Veronika, Grusdat, Melanie, Longworth, Joseph, Guerra, Luana, Kurniawan, Henry, Franchina, Davide G, Soriano-Baguet, Leticia, Binsfeld, Carole, Verschueren, Charlène, Spath, Sabine, Ewen, Anouk, Koncina, Eric, Gérardy, Jean-Jacques, Kobayashi, Takumi, Dostert, Catherine, Farinelle, Sophie, Härm, Janika, Fan, Yu-Tong, Chen, Ying, Harris, Isaac S, Lang, Philipp A, Vasiliou, Vasilis, Waisman, Ari, Letellier, Elisabeth, Becher, Burkhard, Mittelbronn, Michel, Brenner, Dirk

“…The intestinal tract generates significant reactive oxygen species (ROS), but the role of T cell antioxidant mechanisms in maintaining intestinal homeostasis…”
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Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages by He, Wei, Henne, Antonia, Lauterbach, Mario, Geißmar, Eike, Nikolka, Fabian, Kho, Celia, Heinz, Alexander, Dostert, Catherine, Grusdat, Melanie, Cordes, Thekla, Härm, Janika, Goldmann, Oliver, Ewen, Anouk, Verschueren, Charlène, Blay-Cadanet, Julia, Geffers, Robert, Garritsen, Hendrikus, Kneiling, Manfred, Holm, Christian K., Metallo, Christian M., Medina, Eva, Abdullah, Zeinab, Latz, Eicke, Brenner, Dirk, Hiller, Karsten

“…Since its discovery in inflammatory macrophages, itaconate has attracted much attention due to its antimicrobial and immunomodulatory activity 1 – 3 . However,…”
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Isolation of an HIV-1 neutralizing peptide mimicking the CXCR4 and CCR5 surface from the heavy-chain complementary determining region 3 repertoire of a viremic controller by Chevigne, Andy, Delhalle, Sylvie, Counson, Manuel, Beaupain, Nadia, Rybicki, Arkadiusz, Verschueren, Charlène, Staub, Thérèse, Schmit, Jean-Claude, Seguin-Devaux, Carole, Deroo, Sabrina

“…OBJECTIVES:The recent identification of neutralizing antibodies able to prevent viral rebound reemphasized the interest in humoral immune responses to control…”
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Multimeric FHR4 immunoconjugates promote efficient activation of CAP on Her2 tumour cells, further controlled by overexpressed mCRPs, limiting MAC formation and CDC by Plesseria, Jean-Marc, Verschueren, Charlène, Iserentant, Gilles, Cohen, Jacques H.M., Devaux, Carole, Dervillez, Xavier

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The evolution and social determinants of mental health during the first wave of the COVID-19 outbreak in Luxembourg by Ribeiro, Fabiana, Schröder, Valerie E., Krüger, Rejko, Leist, Anja K.

“…•A longitudinal study analysed the mental health of the Luxembourgish population during the first confinement phase.•Women and younger groups presented a…”
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Creation of a pandemic memory by tracing COVID-19 infections and immunity in Luxembourg (CON-VINCE) by Tsurkalenko, Olena, Bulaev, Dmitry, O'Sullivan, Marc Paul, Snoeck, Chantal, Ghosh, Soumyabrata, Kolodkin, Alexey, Rommes, Basile, Gawron, Piotr, Moreno, Carlos Vega, Gomes, Clarissa P C, Kaysen, Anne, Ohnmacht, Jochen, Schröder, Valerie E, Pavelka, Lukas, Meyers, Guilherme Ramos, Pauly, Laure, Pauly, Claire, Hanff, Anne-Marie, Meyrath, Max, Leist, Anja, Sandt, Estelle, Aguayo, Gloria A, Perquin, Magali, Gantenbein, Manon, Abdelrahman, Tamir, Klucken, Jochen, Satagopam, Venkata, Hilger, Christiane, Turner, Jonathan, Vaillant, Michel, Fritz, Joëlle V, Ollert, Markus, Krüger, Rejko

“…During the COVID-19 pandemic swift implementation of research cohorts was key. While many studies focused exclusively on infected individuals, population based…”
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Altered infective competence of the human gut microbiome in COVID-19 by de Nies, Laura, Galata, Valentina, Martin-Gallausiaux, Camille, Despotovic, Milena, Busi, Susheel Bhanu, Snoeck, Chantal J, Delacour, Lea, Budagavi, Deepthi Poornima, Laczny, Cédric Christian, Habier, Janine, Lupu, Paula-Cristina, Halder, Rashi, Fritz, Joëlle V, Marques, Taina, Sandt, Estelle, O'Sullivan, Marc Paul, Ghosh, Soumyabrata, Satagopam, Venkata, Krüger, Rejko, Fagherazzi, Guy, Ollert, Markus, Hefeng, Feng Q, May, Patrick, Wilmes, Paul

“…Infections with SARS-CoV-2 have a pronounced impact on the gastrointestinal tract and its resident microbiome. Clear differences between severe cases of…”
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Optimised multimeric Immuno-conjugates direct selective strong activation of the complement alternative pathway towards Her2-overexpressing tumour cells by Plesseria, Jean-Marc, Verschueren, Charlène, Masquelier, Cécile, Iserentant, Gilles, Cohen, Jacques H.M, Devaux, Carole, Dervillez, Xavier

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