Search Results - "Verrier, L"

The Epileptic Heart: Concept and clinical evidence by Verrier, Richard L., Pang, Trudy D., Nearing, Bruce D., Schachter, Steven C.

“…Sudden unexpected death in epilepsy (SUDEP) is generally considered to result from a seizure, typically convulsive and usually but not always occurring during…”
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Epileptic heart: A clinical syndromic approach by Verrier, Richard L., Pang, Trudy D., Nearing, Bruce D., Schachter, Steven C.

“…Prevention of premature death in patients with chronic epilepsy remains a major challenge. Multiple pathophysiologic factors have been implicated, with intense…”
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Tracking Interlead Heterogeneity of R- and T-Wave Morphology to Disclose Latent Risk for Sudden Cardiac Death by Verrier, Richard L., Ph.D., F.H.R.S, Huikuri, Heikki, M.D

“…Abstract Sudden cardiac death (SCD) due primarily to ventricular fibrillation claims 1.5 million lives worldwide each year. In 45-50% of cases, it is the first…”
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Modified Moving Average T-wave alternans cutpoints by Verrier, Richard L.

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Editorial: Autonomic regulation of cardiovascular function and implications for future therapeutic approaches by KenKnight, Bruce H., Verrier, Richard L.

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Spectrum of clinical applications of interlead ECG heterogeneity assessment: From myocardial ischemia detection to sudden cardiac death risk stratification by Verrier, Richard L., Nearing, Bruce D., D’Avila, Andre

“…Heterogeneity in depolarization and repolarization among regions of cardiac cells has long been recognized as a major factor in cardiac arrhythmogenesis. This…”
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Continuous multi‐day tracking of post‐myocardial infarction recovery of cardiac electrical stability and autonomic tone using electrocardiogram patch monitors by Verrier, Richard L., Varma, Niraj, Nearing, Bruce D.

“…Background Sudden cardiac death (SCD) risk is elevated following acute myocardial infarction (MI). The time course of SCD susceptibility post‐MI requires…”
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Multifactorial Benefits of Chronic Vagus Nerve Stimulation on Autonomic Function and Cardiac Electrical Stability in Heart Failure Patients With Reduced Ejection Fraction by Verrier, Richard L, Libbus, Imad, Nearing, Bruce D, KenKnight, Bruce H

“…Heart failure with reduced left ventricular ejection fraction is a progressive disease that claims > 352,000 lives annually in the United States alone. Despite…”
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Heart rate, autonomic markers, and cardiac mortality by Verrier, Richard L., PhD, Tan, Alex, MD

“…Heart rate is a precisely regulated variable, which plays a critical role in health and disease. Numerous epidemiologic studies and large post-myocardial…”
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The Epileptic Heart Syndrome: Epidemiology, pathophysiology and clinical detection by Verrier, Richard L., Schachter, Steven C.

“…•Population studies report increased cardiovascular events, mortality in epilepsy.•Recurring seizures damage heart and vasculature, the “Epileptic Heart…”
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Empagliflozin's role in reducing ventricular repolarization heterogeneity: insights into cardiovascular mortality decline from the EMPATHY-HEART trial by Lauretti, Cristiane, Antonio, Graziella L, Fernandes, Ariana E, Stocco, Fernando G, Girardi, Adriana C C, Verrier, Richard L, Caramelli, Bruno

“…The incidence of myocardial infarction (MI) and sudden cardiac death (SCD) is significantly higher in individuals with Type 2 Diabetes Mellitus (T2DM) than in…”
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The brain-heart connection: Value of concurrent ECG and EEG recordings in epilepsy management by Slater, Jeremy D., Benbadis, Selim, Verrier, Richard L.

“…•Chronic epilepsy can increase risk for both atrial and ventricular arrhythmias.•Autonomic dysfunction has been implicated as a trigger of cardiac events.•Dual…”
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Autonomic regulation therapy suppresses quantitative T-wave alternans and improves baroreflex sensitivity in patients with heart failure enrolled in the ANTHEM-HF study by Libbus, Imad, PhD, Nearing, Bruce D., PhD, Amurthur, Badri, MS, KenKnight, Bruce H., PhD, Verrier, Richard L., PhD, FHRS

“…Background Autonomic regulation therapy (ART) with chronic vagus nerve stimulation improves ventricular function in patients with chronic heart failure, but…”
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Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode by Belzeaux, R, Bergon, A, Jeanjean, V, Loriod, B, Formisano-Tréziny, C, Verrier, L, Loundou, A, Baumstarck-Barrau, K, Boyer, L, Gall, V, Gabert, J, Nguyen, C, Azorin, J-M, Naudin, J, Ibrahim, E C

“…To date, it remains impossible to guarantee that short-term treatment given to a patient suffering from a major depressive episode (MDE) will improve long-term…”
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If inhibition in the atrioventricular node by ivabradine causes rate-dependent slowing of conduction and reduces ventricular rate during atrial fibrillation by Verrier, Richard L., PhD, Bonatti, Rodolfo, BS, Silva, Ana F.G., BS, Batatinha, Julio A.P., BS, Nearing, Bruce D., PhD, Liu, Gongxin, PhD, Rajamani, Sridharan, PhD, Zeng, Dewan, PhD, Belardinelli, Luiz, MD

“…Background If channels are functionally expressed in atrioventricular (AV) nodal tissue. Objective The purpose of this study was to address whether the…”
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Mechanisms of ranolazine's dual protection against atrial and ventricular fibrillation by Verrier, Richard L, Kumar, Kapil, Nieminen, Tuomo, Belardinelli, Luiz

“…Coronary artery disease and heart failure carry concurrent risk for atrial fibrillation and life-threatening ventricular arrhythmias. We review evidence…”
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Air Pollution and Incidence of Cardiac Arrhythmia by Peters, Annette, Liu, Emerson, Verrier, Richard L., Schwartz, Joel, Gold, Diane R., Mittleman, Murray, Baliff, Jeff, Oh, J. Annie, Allen, George, Monahan, Kevin, Dockery, Douglas W.

“…Air pollution episodes have been associated with increased cardiovascular hospital admissions and mortality in time-series studies. We tested the hypothesis…”
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Optimizing flecainide plasma concentration profile for atrial fibrillation conversion while minimizing adverse ventricular effects by rapid, low-dose intratracheal or intravenous administration by Marum, Alexandre A., Silva, Bruna A., Bortolotto, Alexandre L., Silva, Anderson C., de Antonio, Victor Z., Belardinelli, Luiz, Verrier, Richard L.

“…We investigated whether rapid administration of a low dose of flecainide, either intratracheally or intravenously (IV), could accelerate conversion of atrial…”
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Basis for sudden cardiac death prediction by T-wave alternans from an integrative physiology perspective by Verrier, Richard L., PhD, Kumar, Kapil, MD, Nearing, Bruce D., PhD

“…Detection of microvolt levels of T-wave alternans (TWA) has been shown to be useful in identifying individuals at heightened risk for sudden cardiac death. The…”
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The Selective Cardiac Late Sodium Current Inhibitor GS-458967 Suppresses Autonomically Triggered Atrial Fibrillation in an Intact Porcine Model by CARNEIRO, JULIANA SARAN, BENTO, AFONSO S. ALVES, BACIC, DANILO, NEARING, BRUCE D., RAJAMANI, SRIDHARAN, BELARDINELLI, LUIZ, VERRIER, RICHARD L.

“…GS‐967 Suppresses AF Introduction The anti‐atrial fibrillation (AF) effects of GS‐458967 (GS‐967), a selective, potent inhibitor of cardiac late Na+ current…”
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