Search Results - "Verret, Laure"

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model by Verret, Laure, Mann, Edward O., Hang, Giao B., Barth, Albert M.I., Cobos, Inma, Ho, Kaitlyn, Devidze, Nino, Masliah, Eliezer, Kreitzer, Anatol C., Mody, Istvan, Mucke, Lennart, Palop, Jorge J.

“…Alzheimer's disease (AD) results in cognitive decline and altered network activity, but the mechanisms are unknown. We studied human amyloid precursor protein…”
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Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model by Sanchez, Pascal E, Zhu, Lei, Verret, Laure, Vossel, Keith A, Orr, Anna G, Cirrito, John R, Devidze, Nino, Ho, Kaitlyn, Yu, Gui-Qiu, Palop, Jorge J, Mucke, Lennart

“…In light of the rising prevalence of Alzheimer’s disease (AD), new strategies to prevent, halt, and reverse this condition are needed urgently. Perturbations…”
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Early onset of hypersynchronous network activity and expression of a marker of chronic seizures in the Tg2576 mouse model of Alzheimer's disease by Bezzina, Charlotte, Verret, Laure, Juan, Cécile, Remaud, Jessica, Halley, Hélène, Rampon, Claire, Dahan, Lionel

“…Cortical and hippocampal hypersynchrony of neuronal networks seems to be an early event in Alzheimer's disease pathogenesis. Many mouse models of the disease…”
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Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory by Domínguez, Soledad, Rey, Christophe Clément, Therreau, Ludivine, Fanton, Aurélien, Massotte, Dominique, Verret, Laure, Piskorowski, Rebecca Ann, Chevaleyre, Vivien

“…Adolescence is a vulnerable period characterized by major cognitive changes. The mechanisms underlying the emergence of new cognitive functions are poorly…”
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Ventral tegmental area dopamine projections to the hippocampus trigger long-term potentiation and contextual learning by Sayegh, Fares J. P., Mouledous, Lionel, Macri, Catherine, Pi Macedo, Juliana, Lejards, Camille, Rampon, Claire, Verret, Laure, Dahan, Lionel

“…In most models of neuronal plasticity and memory, dopamine is thought to promote the long-term maintenance of Long-Term Potentiation (LTP) underlying memory…”
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Modifications of hippocampal circuits and early disruption of adult neurogenesis in the tg2576 mouse model of Alzheimer's disease by Krezymon, Alice, Richetin, Kevin, Halley, Hélène, Roybon, Laurent, Lassalle, Jean-Michel, Francès, Bernard, Verret, Laure, Rampon, Claire

“…At advanced stages of Alzheimer's disease, cognitive dysfunction is accompanied by severe alterations of hippocampal circuits that may largely underlie memory…”
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Enriched environmental exposure reduces the onset of action of the serotonin norepinephrin reuptake inhibitor venlafaxine through its effect on parvalbumin interneurons plasticity in mice by Coutens, Basile, Lejards, Camille, Bouisset, Guillaume, Verret, Laure, Rampon, Claire, Guiard, Bruno P.

“…Mood disorders are associated with hypothalamic-pituitary-adrenal axis overactivity resulting from a decreased inhibitory feedback exerted by the hippocampus…”
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Altered inhibitory function in hippocampal CA2 contributes in social memory deficits in Alzheimer’s mouse model by Rey, Christophe Clément, Robert, Vincent, Bouisset, Guillaume, Loisy, Maïthé, Lopez, Sébastien, Cattaud, Vanessa, Lejards, Camille, Piskorowski, Rebecca Ann, Rampon, Claire, Chevaleyre, Vivien, Verret, Laure

“…Parvalbumin (PV)-expressing interneurons which are often associated with the specific extracellular matrix perineuronal net (PNN) play a critical role in the…”
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A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep by Verret, Laure, Goutagny, Romain, Fort, Patrice, Cagnon, Laurène, Salvert, Denise, Léger, Lucienne, Boissard, Romuald, Salin, Paul, Peyron, Christelle, Luppi, Pierre-Hervé

“…Peptidergic neurons containing the melanin-concentrating hormone (MCH) and the hypocretins (or orexins) are intermingled in the zona incerta, perifornical…”
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Paradoxical (REM) sleep genesis: The switch from an aminergic–cholinergic to a GABAergic–glutamatergic hypothesis by Luppi, Pierre-Hervé, Gervasoni, Damien, Verret, Laure, Goutagny, Romain, Peyron, Christelle, Salvert, Denise, Leger, Lucienne, Fort, Patrice

“…In the middle of the last century, Michel Jouvet discovered paradoxical sleep (PS), a sleep phase paradoxically characterized by cortical activation and rapid…”
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Localization of the neurons active during paradoxical (REM) sleep and projecting to the locus coeruleus noradrenergic neurons in the rat by Verret, Laure, Fort, Patrice, Gervasoni, Damien, Léger, Lucienne, Luppi, Pierre-Hervé

“…Locus coeruleus (LC) noradrenergic neurons are active during wakefulness, slow their discharge rate during slow wave sleep, and stop firing during paradoxical…”
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Effects of the genetic background on cognitive performances of TG2576 mice by Lassalle, Jean Michel, Halley, Hélène, Daumas, Stéphanie, Verret, Laure, Francés, Bernard

“…Animal models of genetic diseases obtained by transferring human mutated genes in the mouse are widely used in biomedical based research. They constitute…”
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Early disruption of parvalbumin expression and perineuronal nets in the hippocampus of the Tg2576 mouse model of Alzheimer's disease can be rescued by enriched environment by Cattaud, Vanessa, Bezzina, Charlotte, Rey, Christophe C., Lejards, Camille, Dahan, Lionel, Verret, Laure

“…Recent findings show that parvalbumin (PV) interneuron function is impaired in Alzheimer's disease (AD), and that this impairment in PV function can be linked…”
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Ventral tegmental area dopamine projections to the hippocampus trigger longterm potentiation and contextual learning by Sayegh, Fares, Mouledous, Lionel, Macri, Catherine, Macedo, Juliana Pi, Lejards, Camille, Rampon, Claire, Verret, Laure, Dahan, Lionel

“…In most models of neuronal plasticity and memory, dopamine is thought to promote the long-term maintenance of Long-Term Potentiation (LTP) underlying memory…”
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Sequential inhibitory plasticities in hippocampal area CA2 and social memory formation by Loisy, Maïthé, Bouisset, Guillaume, Lopez, Sébastien, Muller, Maud, Spitsyn, Alena, Duval, Jeanne, Piskorowski, Rebecca Ann, Verret, Laure, Chevaleyre, Vivien

“…Area CA2 is a critical region for diverse hippocampal functions including social recognition memory. This region has unique properties and connectivity…”
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No major effect of dopamine receptor 1/5 antagonist SCH‐23390 on epileptic activity in the Tg2576 mouse model of amyloidosis by B. Szabo, Anna, Sayegh, Farès, Gauzin, Sèbastien, Lejards, Camille, Guiard, Bruno, Valton, Luc, Verret, Laure, Rampon, Claire, Dahan, Lionel

“…The excitation‐inhibition imbalance manifesting as epileptic activities in Alzheimer's disease is gaining more and more attention, and several potentially…”
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Transsynaptic Progression of Amyloid-β-Induced Neuronal Dysfunction within the Entorhinal-Hippocampal Network by Harris, Julie A., Devidze, Nino, Verret, Laure, Ho, Kaitlyn, Halabisky, Brian, Thwin, Myo T., Kim, Daniel, Hamto, Patricia, Lo, Iris, Yu, Gui-Qiu, Palop, Jorge J., Masliah, Eliezer, Mucke, Lennart

“…The entorhinal cortex (EC) is one of the earliest affected, most vulnerable brain regions in Alzheimer's disease (AD), which is associated with amyloid-β (Aβ)…”
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Neuronal hyperexcitability in the Tg2576 mouse model of Alzheimer's disease – the influence of sleep and noradrenergic transmission by B． Szabo, Anna, Cattaud, Vanessa, Bezzina, Charlotte, Dard, Robin F., Sayegh, Fares, Gauzin, Sebastien, Lejards, Camille, Valton, Luc, Rampon, Claire, Verret, Laure, Dahan, Lionel

“…The link between Alzheimer's disease (AD) and network hypersynchrony – manifesting as epileptic activities – received considerable attention in the past…”
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Transient enriched housing before amyloidosis onset sustains cognitive improvement in Tg2576 mice by Verret, Laure, Krezymon, Alice, Halley, Hélène, Trouche, Stéphanie, Zerwas, Meike, Lazouret, Marine, Lassalle, Jean-Michel, Rampon, Claire

“…Abstract Levels of educational and occupational attainment, as components of cognitive reserve, may modify the relationship between the pathological hallmarks…”
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Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory by Domínguez, Soledad, Rey, Christophe Clément, Therreau, Ludivine, Fanton, Aurélien, Massotte, Dominique, Verret, Laure, Piskorowski, Rebecca Ann, Chevaleyre, Vivien

“…Adolescence is a vulnerable period characterized by major cognitive changes. The mechanisms underlying the emergence of new cognitive functions are poorly…”
Get full text