Search Results - "Veronese, ML"

Exposure-Dependent Inhibition of Intestinal and Hepatic CYP3A4 In Vivo by Grapefruit Juice by Veronese, Maria L., Gillen, Lisa P., Burke, Joanne P., Dorval, Ellen P., Hauck, Walter W., Pequignot, Ed, Waldman, Scott A., Greenberg, Howard E.

“…Consumption of typical quantities of grapefruit juice (GFJ) increases the oral bioavailability of several CYP3A4 substrates without affecting their…”
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Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations by Hyman, David M, Puzanov, Igor, Subbiah, Vivek, Faris, Jason E, Chau, Ian, Blay, Jean-Yves, Wolf, Jürgen, Raje, Noopur S, Diamond, Eli L, Hollebecque, Antoine, Gervais, Radj, Elez-Fernandez, Maria Elena, Italiano, Antoine, Hofheinz, Ralf-Dieter, Hidalgo, Manuel, Chan, Emily, Schuler, Martin, Lasserre, Susan Frances, Makrutzki, Martina, Sirzen, Florin, Veronese, Maria Luisa, Tabernero, Josep, Baselga, José

“…In a basket trial that included patients with a variety of cancers, all of which contained a BRAF V600 mutation, the rate of response to vemurafenib was highly…”
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Mechanisms of Hypertension Associated With BAY 43-9006 by VERONESE, Maria Luisa, MOSENKIS, Ari, FLAHERTY, Keith T, GALLAGHER, Maryann, STEVENSON, James P, TOWNSEND, Raymond R, O'DWYER, Peter J

“…BAY 43-9006 (sorafenib) is an inhibitor of Raf kinase, the vascular endothelial growth factor (VEGF) receptor-2, and angiogenesis in tumor xenografts. The…”
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Monoclonal antibodies in the treatment of colorectal cancer by Veronese, Maria Luisa, O'Dwyer, Peter J.

“…Monoclonal antibodies have been developed to target specific proteins involved in the development and progression of cancer. These reagents have the advantage…”
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The Efficacy of Vemurafenib in Erdheim-Chester Disease and Langerhans Cell Histiocytosis: Preliminary Results from VE-Basket Study by Hyman, David M., Diamond, Eli, Subbiah, Vivek, Blay, Jean-Yves, Lockhart, A. Craig, Abdel-Wahab, Omar, Sirzen, Florin, Veronese, Maria Luisa, Laserre, Susan Frances, Elez, Elena, Baselga, Jose

“…Background: The systemic histiocytic disorders Erdheim-Chester disease (ECD) and Langerhans cell histiocytosis (LCH) are rare hematologic malignancies with…”
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Identification of a Gene at 11q23 Encoding a Guanine Nucleotide Exchange Factor: Evidence for Its Fusion with MLL in Acute Myeloid Leukemia by Kourlas, Peter J., Strout, Matthew P., Becknell, Brian, Veronese, Maria Luisa, Croce, Carlo M., Theil, Karl S., Krahe, Ralf, Ruutu, Tapani, Knuutila, Sakari, Bloomfield, Clara D., Caligiuri, Michael A.

“…We have identified a gene at 11q23, telomeric to MLL, that encodes a guanine nucleotide exchange factor (GEF). This gene is transcribed into a 9.5-kb mRNA…”
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The FHIT Gene at 3p14.2 Is Abnormal in Lung Cancer by Sozzi, Gabriella, Veronese, Maria Luisa, Negrini, Massimo, Baffa, Raffaele, Cotticelli, Maria Grazia, Inoue, Hiroshi, Tornielli, Silvana, Pilotti, Silvana, De Gregorio, Laura, Pastorino, Ugo, Pierotti, Marco A, Ohta, Masataka, Huebner, Kay, Croce, Carlo M

“…To determine the role of the FHIT gene, which encompasses the fragile site at 3p14.2, we analyzed 59 tumors of the small cell and non-small cell type by…”
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A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer by VERONESE, M. L, SUN, W, GIANTONIO, B, BERLIN, J, SHULTS, J, DAVIS, L, HALLER, D. G, O'DWYER, P. J

“…Inhibition of epidermal growth factor receptor (EGFR) signalling contributes to the therapy of colorectal cancer. Gefitinib, an oral EGFR tyrosine kinase…”
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FHIT Gene Alterations in Head and Neck Squamous Cell Carcinomas by Virgilio, Laura, Shuster, Michele, Gollin, Susanne M., Veronese, Maria Luisa, Ohta, Masataka, Huebner, Kay, Croce, Carlo M.

“…To determine whether the FHIT gene at 3p14.2 is altered in head and neck squamous cell carcinomas (HNSCC), we examined 26 HNSCC cell lines for deletions within…”
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An open-label, multicenter safety study of vemurafenib (PLX4032, RO5185426) in patients with metastatic melanoma by Larkin, James M. G., Queirolo, Paola, Arance, Ana M, Brown, Michael Paul, Hauschild, Axel, Del Vecchio, Michele, McArthur, Grant A., Neyns, Bart, Becker, Jürgen C., Hansson, Johan, Hogg, David, Ascierto, Paolo Antonio, Loquai, Carmen, Espinosa, Enrique, Garbe, Claus, Patel, Poulam M, Schachter, Jacob, Mitchell, Lada, Veronese, Maria Luisa, Blank, Christian U.

“…Abstract only 8517 Background: Vemurafenib, a BRAF inhibitor, is associated with improved PFS and OS in patients (pts) with BRAF V600 -mutant metastatic…”
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Structure and expression of the human FHIT gene in normal and tumor cells by DRUCK, T, HADACZEK, P, ROTHSTEIN, J, MCCUE, P, COTTICELLI, M. G, INOUE, H, CROCE, C. M, HUEBNER, K, FU, T.-B, OHTA, M, SIPRASHVILI, Z, BAFFA, R, NEGRINI, M, KASTURY, K, VERONESE, M. L, ROSEN, D

“…The FHIT gene, encoded by 10 exons in a 1.1-kb transcript, encompasses approximately 1 Mb of genomic DNA, which includes the hereditary RCC t(3;8)…”
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Loss of FHIT expression in gastric carcinoma by BAFFA, R, VERONESE, M. L, SANTORO, R, MANDES, B, PALAZZO, J. P, RUGGE, M, SANTORO, E, CROCE, C. M, HUEBNER, K

“…Loss of heterozygosity involving the short arm of chromosome 3 has been reported in gastric and other human tumors. We have cloned and mapped a candidate tumor…”
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Association between cigarette smoking and FHIT gene alterations in lung cancer by SOZZI, G, SARD, L, INCARBONE, M, CHELLA, A, ANGELETTI, C. A, PASTORINO, U, HUEBNER, K, BEVILAQUA, G, PILOTTI, S, CROCE, C. M, PIEROTTI, M. A, DE GREGORIO, L, MARCHETTI, A, MUSSO, K, BUTTITTA, F, TORNIELLI, S, PELLEGRINI, S, VERONESE, M. L, MANENTI, G

“…Epidemiologic data have strongly indicated that cigarette smoking is linked to the development of lung cancer. However, little is known of the molecular…”
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Absence of Fhit protein in primary lung tumors and cell lines with FHIT gene abnormalities by SOZZI, G, TORNIELLI, S, GOLDSTRAW, P, HUEBNER, K, CROCE, C. M, PIEROTTI, M. A, TAGLIABUE, E, SARD, L, PEZZELLA, F, PASTORINO, U, MINOLETTI, F, PILOTTI, S, RATCLIFFE, C, VERONESE, M. L

“…Genomic alterations and abnormal expression of the FHIT gene at 3p14.2 have been observed in cell lines and primary tumors of the lung. To correlate FHIT locus…”
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Phase I study of the novel taxane CT-2103 in patients with advanced solid tumors by VERONESE, Maria Luisa, FLAHERTY, Keith, KRAMER, Amy, KONKLE, Barbara A, MORGAN, Mark, STEVENSON, James P, O'DWYER, Peter J

“…CT-2103 (Cell Therapeutics, Seattle, Wash.) is a water-soluble macromolecular conjugate of paclitaxel to a polyglutamate backbone, designed to enhance tumor…”
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Cytogenetic Profile of Lymphoma of Follicle Mantle Lineage: Correlation With Clinicobiologic Features by Cuneo, Antonio, Bigoni, Renato, Rigolin, Gian Matteo, Roberti, Maria Grazia, Bardi, Antonella, Piva, Nadia, Milani, Raffaella, Bullrich, Florencia, Veronese, Maria Luisa, Croce, Carlo, Birg, Françoise, Döhner, Hartmut, Hagemeijer, Anne, Castoldi, Gianluigi

“…Conventional chromosome analysis (CCA) and interphase fluorescence in situ hybridization (FISH) was performed in 42 patients with mantle-cell lymphoma (MCL),…”
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Minimal Region of Loss at 13q14 in B-Cell Chronic Lymphocytic Leukemia by Bullrich, Florencia, Veronese, Maria Luisa, Kitada, Shinichi, Jurlander, Jesper, Caligiuri, Michael A., Reed, John C., Croce, Carlo M.

“…Allelic loss at nonrandom chromosomal sites is thought to mark the position of tumor suppressor genes involved in the pathogenesis and progression of human…”
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Effect of Mibefradil on CYP3A4 In Vivo by Veronese, Maria L., Gillen, Lisa P., Dorval, Ellen P., Hauck, Walter W., Waldman, Scott A., Greenberg, Howard E.

“…Mibefradil, a calcium channel blocker, was removed from the market because of adverse drug interactions with coadministered CYP3A4 substrates. This study…”
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Phase I trial of UFT/leucovorin and irinotecan in patients with advanced cancer by Veronese, M.L., Stevenson, J.P., Sun, W., Redlinger, M., Algazy, K., Giantonio, B., Hahn, S., Vaughn, D., Thorn, C., Whitehead, A.S., Haller, D.G., O'Dwyer, P.J.

“…UFT (BMS-200604, Uftoral®) is an oral fluoropyrimidine that combines uracil and the 5-fluorouracil (5-FU) prodrug, ftorafur, in a 4:1 molar ratio with…”
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Aberrant FHIT transcripts in Merkel cell carcinoma by SOZZI, G, ALDER, H, CROCE, C. M, TORNIELLI, S, CORLETTO, V, BAFFA, R, VERONESE, M. L, NEGRINI, M, PILOTTI, S, PIEROTTI, M. A, HUEBNER, K

“…Merkel cell carcinoma is a rare neuroendocrine carcinoma of the skin which shares several features with small cell lung carcinoma. In a previous study, we…”
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