Search Results - "Vernole, P"

Poly (ADP-ribose) polymerase inhibitor increases apoptosis and reduces necrosis induced by a DNA minor groove binding methyl sulfonate ester by Tentori, L, Balduzzi, A, Portarena, I, Levati, L, Vernole, P, Gold, B, Bonmassar, E, Graziani, G

“…The poly(ADP-ribose) polymerase (PARP) is involved in cell recovery from DNA damage, such as methylation of N3-adenine, that activates the base excision repair…”
Get full text

Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components by TENTORI, Lucio, PORTARENA, Ilaria, VERNOLE, Patrizia, DE FABRITIIS, Paolo, MADAIO, Raffaele, BALDUZZI, Alessandra, ROY, Rabindra, BONMASSAR, Enzo, GRAZIANI, Grazia

“…To evaluate the antitumor activity of single versus split exposure of neoplastic cells to temozolomide (TZM) and poly(ADP-ribose) polymerase (PARP) inhibitor…”
Get full text

Induction of apoptosis by bleomycin in resting and cycling human lymphocytes by Vernole, P., Tedeschi, B., Caporossi, D., Maccarrone, M., Melino, G., Annicchiarico-Petruzzelli, M.

“…Bleomycin induces DNA and chromosome breakage. The differential sensitivity to the drug has been used in vitro to identify individuals at high risk of…”
Get full text

Digoxigenin-labeled probes can detect single-copy genes in human metaphase chromosomes by Vernole, P

“…A technique of in situ hybridization on metaphases of chromosomes by a digoxigenin-labeled probe is described. This technique was able to detect single DNA…”
Get more information

Cytogenetic effects in lymphocytes from children exposed to radiation fall-out after the Chernobyl accident by Padovani, L, Stronati, L, Mauro, F, Testa, A, Appolloni, M, Anzidei, P, Caporossi, D, Tedeschi, B, Vernole, P

“…In a previous paper we reported that a group of children exposed to ionizing radiation following the Chernobyl accident exhibited an appreciable number of…”
Get full text

In vitro effects of growth hormone (GH) and insulin-like growth factor I and II (IGF-I and -II) on chromosome fragility and p53 protein expression in human lymphocytes by CIANFARANI, S, TEDESCHI, B, GERMANI, D, PRETE, S. P, ROSSI, P, VERNOLE, P, CAPOROSSI, D, BOSCHERINI, B

“…Background We have reported previously that growth hormone (GH) therapy increases cell radiosensitivity; in this study we tested whether GH itself or IGFs…”
Get full text

Methods for Checking Cell Cycle Checkpoints by Vernole, P

Get full text

In vitro infection of leukemic bone marrow with HTLV-I generates immortalized cell lines expressing T or myeloid cell phenotype by Giuliani, A, Vernole, P, D'Atri, S, Del Poeta, G, D'Onofrio, C, Faraoni, I, Greiner, J W, Bonmassar, E, Graziani, G

“…Leukemic bone marrow cells ( > 90% blasts) of a patient with acute myeloblastic leukemia (AML), non-treated or pretreated in vitro with a mutagenic triazene…”
Get more information

Enhanced chromosomal fragility in neuroblastoma: correlation with poor prognosis by Vernole, P, Tedeschi, B, Melino, G, Pianca, C, Nicoletti, B

“…In a previous study we demonstrated spontaneous fragility and hypersensitivity to fragile site induction by aphidicolin in lymphocytes from some neuroblastoma…”
Get more information

PARP-1 inhibition decreases Beta-Amyloid-induced neurodegeneration: a cellular and animal model study by Martire⁎, S., Fuso, A., Rotili, D., Muzi, A., Giordano, C., Vernole, P., Lococo, E., Faraldi, M., Masci, A., Miele, A., Graziani, G., Scarpa, S., Mosca, L., d’Erme et al, M.

Get full text

Association of cytogenetic abnormalities in a neuroblastoma and fragile sites expression by VERNOLE, P, CONCATO, C, PIANCA, C, NICOLETTI, B, MELINO, G

“…A 15 month old boy with a stage IV right suprarenal gland neuroblastoma showed a number of raised biochemical parameters, whilst catecholamines and skeletal…”
Get full text

Subregional localization of 14 yeast artificial chromosomes to human chromosome region 1p by fluorescence in situ hybridization by Vernole, P, Caporossi, D, Tedeschi, B, Nicoletti, B, Van Ommen, G J

“…We have sublocalized to the region between 1p22 and 1p33 a total of 14 yeast artificial chromosomes previously assigned to a broader area of human chromosome…”
Get more information

Characterization of a human glioblastoma cell line (LI) expressing hypothalamic and pituitary hormones by SAVARESE, A, ANNICCHIARICO-PETRUZELLI, M, MELINO, G, CITRO, G, ZUPI, G, SPAGNOLI, L. G, COLANTONI, A, VERNOLE, P, STEPHANOU, A, KNIGHT, R. A, GUERRIERI, P

“…The human glioblastoma cell line LI showed morphological features typical of its neuroectodermal origin. Cells were positive by immunofluorescence to GFAP, MHC…”
Get full text

Harnack inequality for harmonic functions relative to a nonlinear p -homogeneous Riemannian Dirichlet form by Biroli, Marco, Vernole, Paola

“…We consider a Riemannian ( p-homogeneous) Dirichlet functional Φ ( u ) = ∫ X μ ( u ) ( d x ) ( p > 1 ) defined on D, where D is a dense subspace of L p ( X , m…”
Get full text

Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells by Vernole, Patrizia, Muzi, Alessia, Volpi, Antonio, Dorio, Annalisa S, Terrinoni, Alessandro, Shah, Girish M, Graziani, Grazia

“…Mismatch repair (MMR) has been shown to control homologous recombination (HR) by aborting strand exchange between divergent sequences. We previously…”
Get more information

An inducible cell line (Natasha), from a neuroblastoma patient with circulating HSR-positive blasts, expressing neurohormones by Melino, G, Vernole, P, Annicchiarico-Petruzzelli, M, Stephanou, A, Colantoni, A, Knight, R A, Spagnoli, L G, Finazzi-Agro, A

“…A cell line, established from a neuroblastoma patient, expresses NCAM and L1 cell adhesion molecules. Two chromosomal abnormalities were present in bone marrow…”
Get more information

Chromosome breakage induced by bleomycin in an ataxia telangiectasia lymphoblastoid line: correlation with fragile sites and Epstein-Barr virus DNA localization by Caporossi, D, Tedeschi, B, Vernole, P, Porfirio, B, Nicoletti, B

“…We have analyzed the distribution of bleomycin-induced breaks in a subline of the ATL9 lymphoblastoid line, derived from peripheral lymphocytes of an ataxia…”
Get more information

Role of mismatch repair in the induction of chromosomal aberrations and sister chromatid exchanges in cells treated with different chemotherapeutic agents by VERNOLE, Patrizia, PEPPONI, Rita, D'ATRI, Stefania

“…The mismatch repair (MMR) system plays a major role in mediating the cytotoxicity and clastogenicity of agents generating O(6)-methylguanine in DNA. Loss of…”
Get full text

Specific sites for EBV association in the Namalwa Burkitt lymphoma cell line and in a lymphoblastoid line transformed in vitro with EBV by Caporossi, D, Vernole, P, Porfirio, B, Tedeschi, B, Frezza, D, Nicoletti, B, Calef, E

“…Localization of Epstein-Barr virus (EBV) DNA was studied by in situ hybridization on chromosomes from the Namalwa Burkitt lymphoma cell line and from a…”
Get more information

Cytogenetic study in lymphocytes from children exposed to ionizing radiation after the Chernobyl accident by Padovani, L, Caporossi, D, Tedeschi, B, Vernole, P, Nicoletti, B, Mauro, F

“…The present study concerns the monitoring of children from the Byelorussian, Ukrainian and Russian republics exposed to the fall-out of the Chernobyl accident…”
Get more information