Search Results - "Vernillo, A T"

Functional sites of chemically modified tetracyclines: inhibition of the oxidative activation of human neutrophil and chicken osteoclast pro-matrix metalloproteinases by Sorsa, T, Ramamurthy, N S, Vernillo, A T, Zhang, X, Konttinen, Y T, Rifkin, B R, Golub, L M

“…We studied the relative ability of 6 different chemically modified non-antimicrobial analogs of tetracycline (CMT) to inhibit human and chicken matrix…”
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Reactive oxygen species activate and tetracyclines inhibit rat osteoblast collagenase by Ramamurthy, Nungavaram S., Vernillo, Anthony T., Greenwald, Robert A., Lee, H.‐M., Sorsa, Timo, Golub, Lorne M., Rifkin, Barry R.

“…Recent studies have demonstrated that tetracyclines (TCs) scavenge reactive oxygen species (ROS). Hypochlorous acid (HOCI), an ROS produced by neutrophils, has…”
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Reduced sialylation of podocalyxin--the major sialoprotein of the rat kidney glomerulus--in aminonucleoside nephrosis by Kerjaschki, D, Vernillo, AT, Farquhar, MG

“…In this study the sugar composition of podocalyxin was determined in puromycin aminonucleoside-treated (PAN) rats and controls. Podocalyxin from both control…”
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The nonantimicrobial properties of tetracycline for the treatment of periodontal disease by Vernillo, A T, Ramamurthy, N S, Golub, L M, Rifkin, B R

“…Tetracyclines have nonantimicrobial properties that appear to modulate host response. In that regard, tetracyclines and their nonantimicrobial chemically…”
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Phenytoin affects osteocalcin secretion from osteoblastic rat osteosarcoma 17/2.8 cells in culture by Vernillo, A T, Rifkin, B R, Hauschka, P V

“…5,5-diphenylhydantoin (Phenytoin, PHT), a widely used anticonvulsant, is also a vitamin K antagonist and disrupts bone metabolism, leading to osteomalacia. The…”
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Effects of tetracyclines on bone metabolism by Vernillo, A T, Rifkin, B R

“…The anti-resorptive properties of tetracyclines (TCs) and their non-antimicrobial, chemically modified analogues (CMTs) have enormous therapeutic potential in…”
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Stimulation of collagen and glycosaminoglycan production by phenytoin 5,5-diphenylhydantoin in monolayer cultures of mesenchymal cells derived from embryonic chick sternae by Vernillo, A T, Schwartz, N B

“…Cultures grown with or without phenytoin (PHT) at a concentration of 5 micrograms/ml from the fifth to the eighth day after plating were labelled with…”
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Calcitonin stimulates cAMP accumulation in chicken osteoclasts by Rifkin, B R, Auszmann, J M, Kleckner, A P, Vernillo, A T, Fine, A S

“…Calcitonin causes an increase in the accumulation of cAMP in mammalian osteoclasts leading to an inhibition of bone resorption. Increases in cAMP subsequent to…”
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Modulation of bone resorption by tetracyclines by Rifkin, B R, Vernillo, A T, Golub, L M, Ramamurthy, N S

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The effect of phenytoin on parathyroid hormone stimulated cAMP activity in cultured murine osteoblasts by Auszmann, J M, Vernillo, A T, Fine, A S, Rifkin, B R

“…Cells were isolated by sequential collagenase digestion from the parietal segments of one day old mice (Swiss albino BNL strain) and characterized for…”
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Cathepsin B and L activities in isolated osteoclasts by Rifkin, B R, Vernillo, A T, Kleckner, A P, Auszmann, J M, Rosenberg, L R, Zimmerman, M

“…Cathepsin B and L activities were examined with chicken osteoclasts isolated by sequential filtration and inhibitors were added to disaggregated rat…”
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Diabetes mellitus: Relevance to dental treatment by Vernillo, Anthony T.

“…(Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91:263-70)…”
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The effect of tetracyclines on collagenase activity in UMR 106-01 rat osteoblastic osteosarcoma cells by Ramamurthy, N S, Vernillo, A T, Lee, H M, Golub, L M, Rifkin, B R

“…Previous studies demonstrated that tetracyclines (TCs) inhibited Type I (interstitial) and Type IV collagenases from different mammalian sources, but there are…”
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Parathyroid hormone regulation of matrix degrading enzymes in rat osteoblastic osteosarcoma 17/2.8 cells by Vernillo, A T, Ramamurthy, N S, Lee, H M, Rifkin, B R

“…The present study was designed to further understand the role of PTH on the secretion of the neutral metalloproteinases, collagenase and gelatinase, from the…”
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The effects of phenytoin (5,5-diphenylhydantoin) on human gingival fibroblasts in culture by Vernillo, A T, Schwartz, N B

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Inhibition of Matrix Metalloproteinase‐Mediated Periodontal Bone Loss in Rats: A Comparison of 6 Chemically Modified Tetracyclines by Ramamurthy, Nungavarum S., Rifkin, Barry R., Greenwald, Robert A., Xu, Jing‐wen, Liu, Yu, Turner, Gloza, Golub, Lorne M., Vernillo, Anthony T.

“…Background: Chemically modified tetracyclines (CMTs), devoid of antimicrobial activity, inhibit pathologically elevated collagenase activity both in vivo and…”
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The effect of phenytoin on collagenase and gelatinase activities in UMR 106-01 rat osteoblastic osteosarcoma cells by Vernillo, A T, Ramamurthy, N S, Lee, H M, Rifkin, B R

“…Phenytoin (PHT), a widely used anticonvulsant, has been shown to inhibit bone resorption in rodent organ cultures. The drug also has complex effects on bone…”
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Blocking periodontal disease progression by inhibiting tissue-destructive enzymes: a potential therapeutic role for tetracyclines and their chemically-modified analogs by Rifkin, B R, Vernillo, A T, Golub, L M

“…Tetracyclines (TCs) have wide therapeutic usage as antimicrobial agents; these drugs (e.g., minocycline, doxycycline) remain useful as adjuncts in periodontal…”
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