Search Results - "Vermeulen, P."

Endosomal Size and Membrane Leakiness Influence Proton Sponge-Based Rupture of Endosomal Vesicles by Vermeulen, Lotte M. P, Brans, Toon, Samal, Sangram K, Dubruel, Peter, Demeester, Jo, De Smedt, Stefaan C, Remaut, Katrien, Braeckmans, Kevin

“…In gene therapy, endosomal escape represents a major bottleneck since nanoparticles often remain entrapped inside endosomes and are trafficked toward the…”
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The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles by Park, Margriet V.D.Z, Neigh, Arianne M, Vermeulen, Jolanda P, de la Fonteyne, Liset J.J, Verharen, Henny W, Briedé, Jacob J, van Loveren, Henk, de Jong, Wim H

“…Abstract Silver nanoparticles are of interest to be used as antimicrobial agents in wound dressings and coatings in medical devices, but potential adverse…”
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International expert panel on inflammatory breast cancer: consensus statement for standardized diagnosis and treatment by Dawood, S., Merajver, S.D., Viens, P., Vermeulen, P.B., Swain, S.M., Buchholz, T.A., Dirix, L.Y., Levine, P.H., Lucci, A., Krishnamurthy, S., Robertson, F.M., Woodward, W.A., Yang, W.T., Ueno, N.T., Cristofanilli, M.

“…Inflammatory breast cancer (IBC) represents the most aggressive presentation of breast cancer. Women diagnosed with IBC typically have a poorer prognosis…”
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A Comparative Linear Interaction Energy and MM/PBSA Study on SIRT1–Ligand Binding Free Energy Calculation by Rifai, Eko Aditya, van Dijk, Marc, Vermeulen, Nico P. E, Yanuar, Arry, Geerke, Daan P

“…Binding free energy (ΔG bind ) computation can play an important role in prioritizing compounds to be evaluated experimentally on their affinity for target…”
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Infiltrating stromal immune cells in inflammatory breast cancer are associated with an improved outcome and increased PD-L1 expression by Van Berckelaer, C, Rypens, C, van Dam, P, Pouillon, L, Parizel, M, Schats, K A, Kockx, M, Tjalma, W A A, Vermeulen, P, van Laere, S, Bertucci, F, Colpaert, C, Dirix, L

“…Inflammatory breast cancer (IBC) is a rare and rapidly progressive form of invasive breast cancer. The aim of this study was to explore the clinical evolution,…”
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Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting by Peeters, D J E, De Laere, B, Van den Eynden, G G, Van Laere, S J, Rothé, F, Ignatiadis, M, Sieuwerts, A M, Lambrechts, D, Rutten, A, van Dam, P A, Pauwels, P, Peeters, M, Vermeulen, P B, Dirix, L Y

“…Background: Molecular characterisation of single circulating tumour cells (CTCs) holds considerable promise for predictive biomarker assessment and to explore…”
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Analytical Solutions of a Space-Time Fractional Derivative of Groundwater Flow Equation by Rusagara, Innocent, Vermeulen, P. D.

“…The classical Darcy law is generalized by regarding the water flow as a function of a noninteger order derivative of the piezometric head. This generalized law…”
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The Effect of Histopathological Growth Patterns of Colorectal Liver Metastases on the Survival Benefit of Adjuvant Hepatic Arterial Infusion Pump Chemotherapy by Filipe, W. F., Meyer, Y. M., Buisman, F. E., van den Braak, R. R. J. Coebergh, Galjart, B., Höppener, D. J., Jarnagin, W. R., Kemeny, N. E., Kingham, T. P., Nierop, P. M. H., van der Stok, E. P., Grünhagen, D. J., Vermeulen, P. B., Groot Koerkamp, B., Verhoef, C., D’Angelica, M. I.

“…Background Histopathological growth patterns (HGPs) are a prognostic biomarker in colorectal liver metastases (CRLM). Desmoplastic HGP (dHGP) is associated…”
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Circulating tumour cell detection: a direct comparison between the CellSearch System, the AdnaTest and CK-19 mammaglobin RT-PCR in patients with metastatic breast cancer by Van der Auwera, I, Peeters, D, Benoy, I H, Elst, H J, Van Laere, S J, Prové, A, Maes, H, Huget, P, van Dam, P, Vermeulen, P B, Dirix, L Y

“…Background: The detection, enumeration and isolation of circulating tumour cells (CTCs) have considerable potential to influence the clinical management of…”
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Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man by Dragovic, Sanja, Vermeulen, Nico P. E., Gerets, Helga H., Hewitt, Philip G., Ingelman‐Sundberg, Magnus, Park, B. Kevin, Juhila, Satu, Snoeys, Jan, Weaver, Richard J.

“…The current test systems employed by pharmaceutical industry are poorly predictive for drug-induced liver injury (DILI). The ‘MIP-DILI’ project addresses this…”
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Integrated miRNA and mRNA expression profiling of the inflammatory breast cancer subtype by Van der Auwera, I, Limame, R, van Dam, P, Vermeulen, P B, Dirix, L Y, Van Laere, S J

“…Background: MicroRNAs (miRNAs) are key regulators of gene expression. In this study, we explored whether altered miRNA expression has a prominent role in…”
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Nano(bio)Materials Do Not Affect Macrophage Phenotype-A Study Conducted by the REFINE Project by David, Christopher A W, Vermeulen, Jolanda P, Gioria, Sabrina, Vandebriel, Rob J, Liptrott, Neill J

“…Macrophages are well known for their involvement in the biocompatibility, as well as biodistribution, of nano(bio)materials. Although there are a number of…”
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First international consensus on the methodology of lymphangiogenesis quantification in solid human tumours by VAN DER AUWERA, I, CAO, Y, TILLE, J. C, PEPPER, M. S, JACKSON, D. G, FOX, S. B, HARRIS, A. L, DIRIX, L. Y, VERMEULEN, P. B

“…The lymphatic system is the primary pathway of metastasis for most human cancers. Recent research efforts in studying lymphangiogenesis have suggested the…”
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Blood microvessel density, lymphatic microvessel density and lymphatic invasion in predicting melanoma metastases: systematic review and meta-analysis by Pastushenko, I., Vermeulen, P.B., Carapeto, F.J., Van den Eynden, G., Rutten, A., Ara, M., Dirix, L.Y., Van Laere, S.

“…Summary In malignant melanoma (MM) there is an urgent need to identify new markers with predictive value superior to the traditional clinical and histological…”
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Histopathological growth patterns of neuroendocrine tumor liver metastases by Meyer, Y., Bohlok, A., Olthof, P., Donckier, V., Doukas, M., Lucidi, V., Vermeulen, P., Grünhagen, D., Verhoef, C.

“…Histopathological growth patterns (HGPs) of liver metastases represent a potential biomarker for prognosis after resection. They have never been studied in…”
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Histopathological growth patterns of colorectal liver metastasis exhibit little heterogeneity and can be determined with a high diagnostic accuracy by Höppener, D. J., Nierop, P. M. H., Herpel, E., Rahbari, N. N., Doukas, M., Vermeulen, P. B., Grünhagen, D. J., Verhoef, C.

“…Colorectal liver metastases (CRLM) exhibit distinct histopathological growth patterns (HGPs) that are indicative of prognosis following surgical treatment…”
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Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates by Koenderink, Jan B., van den Heuvel, Jeroen J. M. W., Bilos, Ab, Vredenburg, Galvin, Vermeulen, Nico P. E., Russel, Frans G. M.

“…Paracetamol (acetaminophen, APAP) overdose is a leading cause of acute drug-induced liver failure. APAP hepatotoxicity is mediated by the reactive metabolite…”
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Detection and prognostic significance of circulating tumour cells in patients with metastatic breast cancer according to immunohistochemical subtypes by Peeters, D J E, van Dam, P-J, Van den Eynden, G G M, Rutten, A, Wuyts, H, Pouillon, L, Peeters, M, Pauwels, P, Van Laere, S J, van Dam, P A, Vermeulen, P B, Dirix, L Y

“…Background: The enumeration of circulating tumour cells (CTCs) with the EpCAM-based CellSearch system has prognostic significance in patients with metastatic…”
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Growth pattern of colorectal liver metastasis as a marker of recurrence risk by Eefsen, R. L., Vermeulen, P. B., Christensen, I. J., Laerum, O. D., Mogensen, M. B., Rolff, H. C., Van den Eynden, G. G., Høyer-Hansen, G., Osterlind, K., Vainer, B., Illemann, M.

“…Despite improved therapy of advanced colorectal cancer, the median overall survival (OS) is still low. A surgical removal has significantly improved survival,…”
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Fly‐scan‐oriented motion analyses and upgraded beamline integration architecture for the High‐Dynamic Double‐Crystal Monochromator at Sirius/LNLS by Geraldes, Renan Ramalho, Luiz, Sergio Augusto Lordano, de Brito Neto, João Leandro, Soares, Telles René Silva, dos Reis, Ricardo Donizeth, Calligaris, Guilherme A., Witvoet, Gert, Vermeulen, J. P. M. B.

“…The High‐Dynamic Double‐Crystal Monochromator (HD‐DCM) is a mechatronic system with unique control‐based architecture and deep paradigm changes as compared…”
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