Search Results - "Vermeer, Louic"

Vectofusin-1, a potent peptidic enhancer of viral gene transfer forms pH-dependent α-helical nanofibrils, concentrating viral particles by Vermeer, Louic S., Hamon, Loic, Schirer, Alicia, Schoup, Michel, Cosette, Jérémie, Majdoul, Saliha, Pastré, David, Stockholm, Daniel, Holic, Nathalie, Hellwig, Petra, Galy, Anne, Fenard, David, Bechinger, Burkhard

“…[Display omitted] Gene transfer using lentiviral vectors has therapeutic applications spanning from monogenic and infectious diseases to cancer. Such gene…”
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Long-term cultivation-independent microbial diversity analysis demonstrates that bacterial communities infecting the adult cystic fibrosis lung show stability and resilience by Stressmann, Franziska Anne, Rogers, Geraint B, van der Gast, Christopher J, Marsh, Peter, Vermeer, Louic S, Carroll, Mary P, Hoffman, Lucas, Daniels, Thomas W V, Patel, Nilesh, Forbes, Benjamin, Bruce, Kenneth Deans

“…Culture-independent analysis of the respiratory secretions of people with cystic fibrosis (CF) has identified many bacterial species not previously detected…”
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Antimicrobial Peptide Potency is Facilitated by Greater Conformational Flexibility when Binding to Gram-negative Bacterial Inner Membranes by Amos, Sarah-Beth T. A., Vermeer, Louic S., Ferguson, Philip M., Kozlowska, Justyna, Davy, Matthew, Bui, Tam T., Drake, Alex F., Lorenz, Christian D., Mason, A. James

“…The interaction of antimicrobial peptides (AMPs) with the inner membrane of Gram-negative bacteria is a key determinant of their abilities to exert diverse…”
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Combined systems approaches reveal highly plastic responses to antimicrobial peptide challenge in Escherichia coli by Kozlowska, Justyna, Vermeer, Louic S, Rogers, Geraint B, Rehnnuma, Nabila, Amos, Sarah-Beth T A, Koller, Garrit, McArthur, Michael, Bruce, Kenneth D, Mason, A James

“…Obtaining an in-depth understanding of the arms races between peptides comprising the innate immune response and bacterial pathogens is of fundamental interest…”
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Conformational Flexibility Determines Selectivity and Antibacterial, Antiplasmodial, and Anticancer Potency of Cationic α-Helical Peptides by Vermeer, Louic S., Lan, Yun, Abbate, Vincenzo, Ruh, Emrah, Bui, Tam T., Wilkinson, Louise J., Kanno, Tokuwa, Jumagulova, Elmira, Kozlowska, Justyna, Patel, Jayneil, McIntyre, Caitlin A., Yam, W.C., Siu, Gilman, Atkinson, R.Andrew, Lam, Jenny K.W., Bansal, Sukhvinder S., Drake, Alex F., Mitchell, Graham H., Mason, A.James

“…We used a combination of fluorescence, circular dichroism (CD), and NMR spectroscopies in conjunction with size exclusion chromatography to help rationalize…”
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Simultaneous Analysis of Secondary Structure and Light Scattering from Circular Dichroism Titrations: Application to Vectofusin-1 by Vermeer, Louic S., Marquette, Arnaud, Schoup, Michel, Fenard, David, Galy, Anne, Bechinger, Burkhard

“…Circular Dichroism data are often decomposed into their constituent spectra to quantify the secondary structure of peptides or proteins but the estimation of…”
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NMR Metabolomics of MTLn3E Breast Cancer Cells Identifies a Role for CXCR4 in Lipid and Choline Regulation by Vermeer, Louic S, Fruhwirth, Gilbert O, Pandya, Pahini, Ng, Tony, Mason, A. James

“…The alpha chemokine receptor CXCR4 is up-regulated in certain types of breast cancer. Truncation of the C-terminus of this receptor alters cell morphology and…”
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Author Correction: Antimicrobial Peptide Potency is Facilitated by Greater Conformational Flexibility when Binding to Gram-negative Bacterial Inner Membranes by Amos, Sarah-Beth T. A., Vermeer, Louic S., Ferguson, Philip M., Kozlowska, Justyna, Davy, Matthew, Bui, Tam T., Drake, Alex F., Lorenz, Christian D., Mason, A. James

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper…”
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Manipulating the pH response of 2,3-diaminopropionic acid rich peptides to mediate highly effective gene silencing with low-toxicity by Abbate, Vincenzo, Liang, Wanling, Patel, Jayneil, Lan, Yun, Capriotti, Luigi, Iacobucci, Valentina, Bui, Tam T., Chaudhuri, Poulami, Kudsiova, Laila, Vermeer, Louic S., Chan, Patrick F.L., Kong, Xiaole, Drake, Alex F., Lam, Jenny K.W., Bansal, Sukhvinder S., Mason, A. James

“…Cationic amphipathic pH responsive peptides possess high in vitro and in vivo nucleic acid delivery capabilities and function by forming a non-covalent complex…”
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Control of pH responsive peptide self-association during endocytosis is required for effective gene transfer by Iacobucci, Valentina, Di Giuseppe, Francesca, Bui, Tam T., Vermeer, Louic S., Patel, Jayneil, Scherman, Daniel, Kichler, Antoine, Drake, Alex F., Mason, A. James

“…Cationic amphipathic histidine rich peptides demonstrate differential nucleic acid binding capabilities at neutral and acidic pH and adopt conformations at…”
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Incorporation of 2,3-Diaminopropionic Acid into Linear Cationic Amphipathic Peptides Produces pH-Sensitive Vectors by Lan, Yun, Langlet-Bertin, Bérangère, Abbate, Vincenzo, Vermeer, Louic S, Kong, Xiaole, Sullivan, Kelly E, Leborgne, Christian, Scherman, Daniel, Hider, Robert C, Drake, Alex F, Bansal, Sukhvinder S, Kichler, Antoine, Mason, A. James

“…Nonviral vectors that harness the change in pH in endosomes, are increasingly being used to deliver cargoes, including nucleic acids, into mammalian cells…”
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A relationship between Pseudomonal growth behaviour and cystic fibrosis patient lung function identified in a metabolomic investigation by Kozlowska, Justyna, Rivett, Damian W., Vermeer, Louic S., Carroll, Mary P., Bruce, Kenneth D., James Mason, A., Rogers, Geraint B.

“…Chronic polymicrobial lung infections in adult cystic fibrosis patients are typically dominated by high levels of Pseudomonas aeruginosa . Determining the…”
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Structural properties of a peptide derived from H +-V-ATPase subunit a by Vermeer, Louic S., Réat, Valérie, Hemminga, Marcus A., Milon, Alain

“…The 3D structure of a peptide derived from the putative transmembrane segment 7 (TM7) of subunit a from H +-V-ATPase from Saccharomyces cerevisiae has been…”
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Conformation of a Peptide Encompassing the Proton Translocation Channel of Vacuolar H +-ATPase by Vos, Werner L., Vermeer, Louic S., Hemminga, Marcus A.

“…The structural properties of a crucial transmembrane helix for proton translocation in vacuolar ATPase are studied using double site-directed spin-labeling…”
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Acyl chain order parameter profiles in phospholipid bilayers: computation from molecular dynamics simulations and comparison with 2H NMR experiments by Vermeer, Louic S, de Groot, Bert L, Réat, Valérie, Milon, Alain, Czaplicki, Jerzy

“…Order parameters from deuterium NMR are often used to validate or calibrate molecular dynamics simulations. This paper gives a short overview of the literature…”
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Decomposition of ESR Spectra Using MALDI-TOF Mass Spectrometry by Vos, Werner L, Vermeer, Louic S, Wolfs, Cor J. A. M, Spruijt, Ruud B, Hemminga, Marcus A

“…ESR (or EPR) spectroscopy on spin-labeled site-directed cysteine mutants is ideally suited for structural studies of membrane proteins due to its high…”
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Incorporation of 2,3-diaminopropionic acid in linear cationic amphipathic peptides produces pH sensitive vectors by Lan, Yun, Langlet-Bertin, Bérangère, Abbate, Vincenzo, Vermeer, Louic S., Kong, Xiaole, Sullivan, Kelly E., Leborgne, Christian, Scherman, Daniel, Hider, Robert C., Drake, Alex F., Bansal, Sukhvinder S., Kichler, Antoine, Mason, A. James

“…Non-viral vectors that harness the change in pH in endosomes are increasingly being used to deliver cargoes, including nucleic acids, to mammalian cells. Here…”
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Solution and Solid-State Nuclear Magnetic Resonance Structural Investigations of the Antimicrobial Designer Peptide GL13K in Membranes by Harmouche, Nicole, Aisenbrey, Christopher, Porcelli, Fernando, Xia, Youlin, Nelson, Sarah E. D, Chen, Xi, Raya, Jesus, Vermeer, Louic, Aparicio, Conrado, Veglia, Gianluigi, Gorr, Sven-Ulrik, Bechinger, Burkhard

“…The antimicrobial peptide GL13K encompasses 13 amino acid residues and has been designed and optimized from the salivary protein BPIFA2 to exhibit potent…”
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The measurement of the β/α anomer composition within amorphous lactose prepared by spray and freeze drying using a simple (1)H-NMR method by Jawad, Rim, Elleman, Carole, Vermeer, Louic, Drake, Alex F, Woodhead, Brendon, Martin, Gary P, Royall, Paul G

“…Reports of the anomeric composition of amorphous lactose are rare and state a highly variable range of composition (between 0% and 60% w/w β content). We aimed…”
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Cell-Penetrating Peptides with Antimicrobial, Transfection and Transduction Activities by Wolf, Justine, Vermeer, Louic, Marquette, Arnaud, Lointier, Morane, Raya, Jesus, Bertani, Philippe, Wilkens Juhl, Dennis, Kichler, Antoine, Gotthardt, Martin, Wittmann, Max, Süss, Regine, Hamon, Loic, Galy, Anne, Fenard, David, Bechinger, Burkhard

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