Search Results - "Verma, Ajit K."

Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone-refractory prostate cancer by Aziz, Moammir H, Dreckschmidt, Nancy E, Verma, Ajit K

“…Prostate cancer (PCa) is the second leading cause of cancer-related deaths in men. Hormone-refractory invasive PCa is the end stage and accounts for the…”
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Plumbagin, a medicinal plant (Plumbago zeylanica)-derived 1,4-naphthoquinone, inhibits growth and metastasis of human prostate cancer PC-3M-luciferase cells in an orthotopic xenograft mouse model by Hafeez, Bilal Bin, Zhong, Weixiong, Fischer, Joseph W., Mustafa, Ala, Shi, Xudong, Meske, Louise, Hong, Hao, Cai, Weibo, Havighurst, Thomas, Kim, KyungMann, Verma, Ajit K.

“…We present here first time that Plumbagin (PL), a medicinal plant-derived 1,4-naphthoquinone, inhibits the growth and metastasis of human prostate cancer (PCa)…”
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Genetic Ablation of PKC Epsilon Inhibits Prostate Cancer Development and Metastasis in Transgenic Mouse Model of Prostate Adenocarcinoma by HAFEEZ, Bilal Bin, WEIXIONG ZHONG, WEICHERT, Jamey, DRECKSCHMIDT, Nancy E, MOHAMMAD SARWAR JAMAL, VERMA, Ajit K

“…Protein kinase C epsilon (PKCε), a novel PKC isoform, is overexpressed in prostate cancer (PCa) and correlates with disease aggressiveness. However, the…”
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Androgen Receptor and Its Splicing Variant 7 Expression in Peripheral Blood Mononuclear Cells and in Circulating Tumor Cells in Metastatic Castration-Resistant Prostate Cancer by Marín-Aguilera, Mercedes, Jiménez, Natalia, Reig, Òscar, Montalbo, Ruth, Verma, Ajit K, Castellano, Giancarlo, Mengual, Lourdes, Victoria, Iván, Pereira, María V, Milà-Guasch, Maria, García-Recio, Susana, Benítez-Ribas, Daniel, Cabezón, Raquel, González, Azucena, Juan, Manel, Prat, Aleix, Mellado, Begoña

“…Androgen receptor (AR) signaling remains crucial in castration-resistant prostate cancer (CRPC). Since it is also essential in immune cells, we studied whether…”
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Unmanned aerial vehicle path planning based on A algorithm and its variants in 3d environment by Mandloi, Dilip, Arya, Rajeev, Verma, Ajit K.

“…Finding a safe and optimum path from the source node to the target node, while preventing collisions with environmental obstacles, is always a challenging…”
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Non-coherent localization with geometric topology of wireless sensor network under target and anchor node perturbations by Prateek, Arya, Rajeev, Verma, Ajit K.

“…This paper investigates non coherent localization of an unknown target node in presence of a symmetrically opposite mirror node while the transmitter anchor…”
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Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKCε, Stat3 and neuroendocrine markers by BIN HAFEEZ, Bilal, WEIXIONG ZHONG, MUSTAFA, Ala, FISCHER, Joseph W, WITKOWSKY, Olya, VERMA, Ajit K

“…Plumbagin (PL), 5-hydroxy-2-methyl-1,4-naphthoquinone, is a quinoid constituent isolated from the roots of the medicinal plant Plumbago zeylanica L. (also…”
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Mouse Models of the Skin: Models to Define Mechanisms of Skin Carcinogenesis by Wheeler, Deric L., Verma, Ajit K., Denning, Mitchell F.

“…[...]they summarize the various mouse models that have helped elucidate the role of this very interesting molecule. In the paper entitled “Multiple roles for…”
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Protein Kinase Cε, Which Is Linked to Ultraviolet Radiation-Induced Development of Squamous Cell Carcinomas, Stimulates Rapid Turnover of Adult Hair Follicle Stem Cells by Singh, Ashok, Singh, Anupama, Sand, Jordan M., Heninger, Erika, Hafeez, Bilal Bin, Verma, Ajit K.

“…To find clues about the mechanism by which kinase C epsilon (PKCε) may impart susceptibility to ultraviolet radiation (UVR)-induced development of cutaneous…”
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Ultraviolet radiation-induced differential microRNA expression in the skin of hairless SKH1 mice, a widely used mouse model for dermatology research by Singh, Ashok, Willems, Estelle, Singh, Anupama, Ong, Irene M, Verma, Ajit K

“…Cutaneous squamous cell carcinoma (cSCC) is the most common type of non-melanoma skin cancer that can metastasize. The major etiological factor associated with…”
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Topically Applied Hsp90 Inhibitor 17AAG Inhibits UVR-Induced Cutaneous Squamous Cell Carcinomas by Singh, Anupama, Singh, Ashok, Sand, Jordan M., Bauer, Samuel J., Hafeez, Bilal Bin, Meske, Louise, Verma, Ajit K.

“…We present here that heat-shock protein 90 (Hsp90) inhibitor 17-(allylamino)-17-demethoxygeldanamycin (17AAG), when topically applied to mouse skin, inhibits…”
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Preamble by Verma, Ajit K., Sadiq, Rehan, Deshpande, Ashok

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Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals by Singh, Ashok, Singh, Anupama, Bauer, Samuel J, Wheeler, Deric L, Havighurst, Thomas C, Kim, KyungMann, Verma, Ajit K

“…Protein kinase C epsilon (PKCε), a Ca(2+)-independent phospholipid-dependent serine/threonine kinase, is among the six PKC isoforms (α, δ, ε, η, μ, ζ)…”
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Aggregated risk of a series of tunnels on Mumbai–Pune expressway by Jena, Jajati K., Verma, Ajit K., Kumar, Uday, Ajit, Srividya

“…In the heavily industrialized western India, on the express way between Mumbai and Pune there is a series of five 03-lane one way tunnels. Risks in the tunnels…”
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Protein kinase Cε, which sensitizes skin to sun's UV radiation-induced cutaneous damage and development of squamous cell carcinomas, associates with stat3 by AZIZ, Moammir H, MANOHARAN, Herbert T, VERMA, Ajit K

“…Chronic exposure to UV radiation (UVR) is the major etiologic factor in the development of human skin cancers including squamous cell carcinoma (SCC). We have…”
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Protein kinase Cε interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer by AZIZ, Moammir H, MANOHARAN, Herbert T, CHURCH, Dawn R, DRECKSCHMIDT, Nancy E, WEIXIONG ZHONG, OBERLEY, Terry D, WILDING, George, VERMA, Ajit K

“…Abstract Prostate cancer is the most common type of cancer in men and ranks second only to lung cancer in cancer-related deaths. The management of locally…”
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Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), isolated from Plumbago zeylanica, inhibits ultraviolet radiation-induced development of squamous cell carcinomas by Sand, Jordan M., Hafeez, Bilal Bin, Jamal, Mohammad Sarwar, Witkowsky, Olya, Siebers, Emily M., Fischer, Joseph, Verma, Ajit K.

“…Plumbagin (PL) (5-hydroxy-2-methyl-1,4-napthoquinone), a medicinal plant-derived naphthoquinone, was isolated from the roots of the Plumbago zeylanica L. (also…”
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Tissue-specific conditional PKCε knockout mice: a model to precisely reveal PKCε functional role in initiation, promotion and progression of cancer by Hafeez, Bilal Bin, Meske, Louise, Singh, Ashok, Singh, Anupama, Zhong, Weixiong, Powers, Patricia, John, Manorama, Griep, Anne E, Verma, Ajit K

“…PKCε is a transforming oncogene and a predictive biomarker of various human cancers. However, a precise in vivo link of PKCε to cancer induction, progression…”
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Phase I Chemoprevention Study of Difluoromethylornithine in Subjects with Organ Transplants by CARBONE, Paul P, PIRSCH, John D, THOMAS, James P, DOUGLAS, Jeffrey A, VERMA, Ajit K, LARSON, Paul O, SNOW, Stephen, TUTSCH, Kendra D, PAUK, Diane

“…Individuals who receive life-saving organ transplants and the required immunosuppression often develop secondary cancers. One of the most common secondary…”
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Protein kinase Cε interacts with Stat3 and regulates its activation that is essential for the development of skin cancer by Aziz, Moammir H., Manoharan, Herbert T., Sand, Jordan M., Verma, Ajit K.

“…Protein kinase C (PKC) represents a large family of phosphatidylserine (PS)‐dependent serine/threonine protein kinases. At least six PKC isoforms (α, δ, ε, η,…”
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