Search Results - "Verjee, Sheela"
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Saffron Flower Extract Promotes Scratch Wound Closure of Keratinocytes and Enhances VEGF Production
Published in Planta medica (01-10-2017)“…During saffron ( ) spice production, large amounts of floral biowaste are generated. It was the aim of this study to develop a value-added product from saffron…”
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Permeation characteristics of hypericin across Caco‐2 monolayers in the presence of single flavonoids, defined flavonoid mixtures or Hypericum extract matrix
Published in Journal of pharmacy and pharmacology (01-01-2019)“…Objectives The major aim of this study was to get a detailed understanding of the exposure and fate of hypericin in the Caco‐2 cell system when combined with…”
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Permeation Characteristics of Hypericin across Caco-2 Monolayers in the Absence or Presence of Quercitrin - A Mass Balance Study
Published in Planta medica (01-08-2015)“…Hypericin is a natural polycyclic quinone found in Hypericum perforatum. Although hypericin reportedly has numerous pharmacological activities, only a limited…”
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Mechanism of chemical degradation and determination of solubility by kinetic modeling of the highly unstable sesquiterpene lactone nobilin in different media
Published in Journal of pharmaceutical sciences (01-10-2014)“…The objective of this work was first to investigate the chemical degradation of the sesquiterpene lactone nobilin and determine its solubility under conditions…”
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Evaluation of the Intestinal Absorption Mechanism of Casearin X in Caco‑2 Cells with Modified Carboxylesterase Activity
Published in Journal of natural products (Washington, D.C.) (22-04-2016)“…The clerodane diterpene casearin X (1), isolated from the leaves of Casearia sylvestris, is a potential new drug candidate due to its potent in vitro cytotoxic…”
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Caco-2 Permeability Studies and In Vitro hERG Liability Assessment of Tryptanthrin and Indolinone
Published in Planta medica (01-08-2016)“…Tryptanthrin and (E,Z)-3-(4-hydroxy-3,5-dimethoxybenzylidene)indolinone (indolinone) were recently isolated from Isatis tinctoria as potent anti-inflammatory…”
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