Search Results - "Verjans, M"

A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61 by Depledge, Daniel P., Ouwendijk, Werner J. D., Sadaoka, Tomohiko, Braspenning, Shirley E., Mori, Yasuko, Cohrs, Randall J., Verjans, Georges M. G. M., Breuer, Judith

“…Varicella-zoster virus (VZV), an alphaherpesvirus, establishes lifelong latent infection in the neurons of >90% humans worldwide, reactivating in one-third to…”
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The architecture of the simian varicella virus transcriptome by Braspenning, Shirley E, Verjans, Georges M G M, Mehraban, Tamana, Messaoudi, Ilhem, Depledge, Daniel P, Ouwendijk, Werner J D

“…Primary infection with varicella-zoster virus (VZV) causes varicella and the establishment of lifelong latency in sensory ganglion neurons. In one-third of…”
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An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells by Lamers, Mart M, van der Vaart, Jelte, Knoops, Kèvin, Riesebosch, Samra, Breugem, Tim I, Mykytyn, Anna Z, Beumer, Joep, Schipper, Debby, Bezstarosti, Karel, Koopman, Charlotte D, Groen, Nathalie, Ravelli, Raimond B G, Duimel, Hans Q, Demmers, Jeroen A A, Verjans, Georges M G M, Koopmans, Marion P G, Muraro, Mauro J, Peters, Peter J, Clevers, Hans, Haagmans, Bart L

“…Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) causes coronavirus disease 2019 (COVID‐19), which may result in acute respiratory distress…”
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Immunobiology of Varicella-Zoster Virus Infection by Laing, Kerry J, Ouwendijk, Werner J D, Koelle, David M, Verjans, Georges M G M

“…Varicella-zoster virus (VZV) causes clinically significant illness during acute and recurrent infection accompanied by robust innate and acquired immune…”
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Neurovirulence of Usutu virus in human fetal organotypic brain slice cultures partially resembles Zika and West Nile virus by Marshall, Eleanor M., Rashidi, Ahmad S., van Gent, Michiel, Rockx, Barry, Verjans, Georges M. G. M.

“…Usutu (USUV), West Nile (WNV), and Zika virus (ZIKV) are neurotropic arthropod-borne viruses (arboviruses) that cause severe neurological disease in humans…”
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Varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency by Ouwendijk, Werner J. D., Depledge, Daniel P., Rajbhandari, Labchan, Lenac Rovis, Tihana, Jonjic, Stipan, Breuer, Judith, Venkatesan, Arun, Verjans, Georges M. G. M., Sadaoka, Tomohiko

“…Varicella-zoster virus (VZV) establishes lifelong neuronal latency in most humans world-wide, reactivating in one-third to cause herpes zoster and occasionally…”
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Humidity-Responsive Liquid Crystalline Polymer Actuators with an Asymmetry in the Molecular Trigger That Bend, Fold, and Curl by de Haan, Laurens T, Verjans, Julien M. N, Broer, Dirk J, Bastiaansen, Cees W. M, Schenning, Albertus P. H. J

“…We show a versatile method for the preparation of a variety of humidity-responsive actuators based on a single sheet of a hydrogen-bonded, uniaxially aligned…”
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Current Perspectives on the Management of Herpesvirus Infections in Solid Organ Transplant Recipients by Malahe, S Reshwan K, van Kampen, Jeroen J A, Manintveld, Olivier C, Hoek, Rogier A S, den Hoed, Caroline M, Baan, Carla C, Kho, Marcia M L, Verjans, Georges M G M

“…Solid organ transplant recipients (SOTRs) are at high risk of human herpesvirus (HHV)-related morbidity and mortality due to the use of immunosuppressive…”
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High Levels of Neutrophil Extracellular Traps Persist in the Lower Respiratory Tract of Critically Ill Patients With Coronavirus Disease 2019 by Ouwendijk, Werner J D, Raadsen, Matthijs P, van Kampen, Jeroen J A, Verdijk, Robert M, von der Thusen, Jan H, Guo, Lihui, Hoek, Rogier A S, van den Akker, Johannes P C, Endeman, Henrik, Langerak, Thomas, Molenkamp, Richard, Gommers, Diederik, Koopmans, Marion P G, van Gorp, Eric C M, Verjans, Georges M G M, Haagmans, Bart L

“…Abstract Lower respiratory tract (LRT) disease induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can deteriorate to acute respiratory…”
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Local CD4 and CD8 T-cell reactivity to HSV-1 antigens documents broad viral protein expression and immune competence in latently infected human trigeminal ganglia by van Velzen, Monique, Jing, Lichen, Osterhaus, Albert D M E, Sette, Alessandro, Koelle, David M, Verjans, Georges M G M

“…Herpes simplex virus type 1 (HSV-1) infection results in lifelong chronic infection of trigeminal ganglion (TG) neurons, also referred to as neuronal HSV-1…”
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Herpes simplex virus infection induces necroptosis of neurons and astrocytes in human fetal organotypic brain slice cultures by Rashidi, Ahmad S, Tran, Diana N, Peelen, Caithlin R, van Gent, Michiel, Ouwendijk, Werner J D, Verjans, Georges M G M

“…Herpes simplex virus (HSV) encephalitis (HSE) is a serious and potentially life-threatening disease, affecting both adults and newborns. Progress in…”
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Neurotropic virus infections as the cause of immediate and delayed neuropathology by Ludlow, Martin, Kortekaas, Jeroen, Herden, Christiane, Hoffmann, Bernd, Tappe, Dennis, Trebst, Corinna, Griffin, Diane E., Brindle, Hannah E., Solomon, Tom, Brown, Alan S., van Riel, Debby, Wolthers, Katja C., Pajkrt, Dasja, Wohlsein, Peter, Martina, Byron E. E., Baumgärtner, Wolfgang, Verjans, Georges M., Osterhaus, Albert D. M. E.

“…A wide range of viruses from different virus families in different geographical areas, may cause immediate or delayed neuropathological changes and…”
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Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration by González-Motos, Víctor, Jürgens, Carina, Ritter, Birgit, Kropp, Kai A, Durán, Verónica, Larsen, Olav, Binz, Anne, Ouwendijk, Werner J D, Lenac Rovis, Tihana, Jonjic, Stipan, Verjans, Georges M G M, Sodeik, Beate, Krey, Thomas, Bauerfeind, Rudolf, Schulz, Thomas F, Kaufer, Benedikt B, Kalinke, Ulrich, Proudfoot, Amanda E I, Rosenkilde, Mette M, Viejo-Borbolla, Abel

“…Varicella zoster virus (VZV) is a highly prevalent human pathogen that establishes latency in neurons of the peripheral nervous system. Primary infection…”
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Phenotypic and functional characterization of T cells in white matter lesions of multiple sclerosis patients by van Nierop, Gijsbert P., van Luijn, Marvin M., Michels, Samira S., Melief, Marie-Jose, Janssen, Malou, Langerak, Anton W., Ouwendijk, Werner J. D., Hintzen, Rogier Q., Verjans, Georges M. G. M.

“…T cells are considered pivotal in the pathology of multiple sclerosis (MS), but their function and antigen specificity are unknown. To unravel the role of T…”
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High seroprevalence of human herpesviruses in HIV-infected individuals attending primary healthcare facilities in rural South Africa by Schaftenaar, Erik, Verjans, Georges M G M, Getu, Sarah, McIntyre, James A, Struthers, Helen E, Osterhaus, Albert D M E, Peters, Remco P H

“…Seroprevalence data of human herpesviruses (HHVs) are limited for sub-Saharan Africa. These are important to provide an indication of potential burden of…”
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T-cells in human trigeminal ganglia express canonical tissue-resident memory T-cell markers by Unger, Peter-Paul A, Oja, Anna E, Khemai-Mehraban, Tamana, Ouwendijk, Werner J D, Hombrink, Pleun, Verjans, Georges M G M

“…Trigeminal ganglia (TG) neurons are the main site of lifelong latent herpes simplex virus type 1 (HSV-1) infection. T-cells in ganglia contribute to long-term…”
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Large, Stable, Contemporary Interspecies Recombination Events in Circulating Human Herpes Simplex Viruses by Casto, Amanda M, Roychoudhury, Pavitra, Xie, Hong, Selke, Stacy, Perchetti, Garrett A, Wofford, Haley, Huang, Meei-Li, Verjans, Georges M G M, Gottlieb, Geoffrey S, Wald, Anna, Jerome, Keith R, Koelle, David M, Johnston, Christine, Greninger, Alexander L

“…Abstract Background The ubiquitous human pathogens, herpes simplex virus (HSV)-1 and HSV-2, are distinct viral species that diverged approximately 6 million…”
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Selective retention of virus-specific tissue-resident T cells in healed skin after recovery from herpes zoster by Laing, Kerry J., Ouwendijk, Werner J. D., Campbell, Victoria L., McClurkan, Christopher L., Mortazavi, Shahin, Elder Waters, Michael, Krist, Maxwell P., Tu, Richard, Nguyen, Nhi, Basu, Krithi, Miao, Congrong, Schmid, D. Scott, Johnston, Christine, Verjans, Georges M. G. M., Koelle, David M.

“…Herpes zoster is a localized skin infection caused by reactivation of latent varicella-zoster virus. Tissue-resident T cells likely control skin infections…”
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Selective retention of herpes simplex virus-specific T cells in latently infected human trigeminal ganglia by Verjans, Georges M.G.M, Hintzen, Rogier Q, van Dun, Jessica M, Poot, Angelique, Milikan, Johannes C, Laman, Jon D, Langerak, Anton W, Kinchington, Paul R, Osterhaus, Albert D.M.E

“…Primary infection with herpes simplex virus 1 (HSV-1) and varicella zoster virus (VZV) results in lifelong latent infections of neurons in sensory ganglia such…”
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Varicella-zoster virus proteome-wide T-cell screening demonstrates low prevalence of virus-specific CD8 T-cells in latently infected human trigeminal ganglia by van Gent, Michiel, Ouwendijk, Werner J D, Campbell, Victoria L, Laing, Kerry J, Verjans, Georges M G M, Koelle, David M

“…Trigeminal ganglia (TG) neurons are an important site of lifelong latent varicella-zoster virus (VZV) infection. Although VZV-specific T-cells are considered…”
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