Search Results - "Verity, M. Anthony"

Lipin-1 Regulates Autophagy Clearance and Intersects with Statin Drug Effects in Skeletal Muscle by Zhang, Peixiang, Verity, M. Anthony, Reue, Karen

“…LPIN1 encodes lipin-1, a phosphatidic acid phosphatase (PAP) enzyme that catalyzes the dephosphorylation of phosphatidic acid to form diacylglycerol…”
Get full text

Abnormalities of Calcium Handling Proteins in Skeletal Muscle Mirror Those of the Heart in Humans With Heart Failure: A Shared Mechanism? by Middlekauff, Holly R., MD, Vigna, Chris, MS, Verity, M. Anthony, MD, Fonarow, Gregg C., MD, Horwich, Tamara B., MD, Hamilton, Michele A., MD, Shieh, Perry, MD, PhD, Tupling, A. Russell, PhD

“…Abstract Background In the failing human heart, abnormalities of Ca2+ cycling have been described, but there is scant knowledge about Ca2+ handling in the…”
Get full text

Diagnostic uncertainty in the inflammatory myopathies by Verity, M. Anthony, MD

“…A group of case histories with appropriate muscle biopsy findings is presented to demonstrate some atypical presentations of the inflammatory myopathies…”
Get full text

Nicotinamide Adenine Dinucleotide Tetrazolium Reductase Identifies Microvasculature Activation in Muscle from Adult Patients with Dermatomyositis by CHARLES-SCHOEMAN, Christina, VERITY, M. Anthony

“…Previous work has suggested involvement of the muscle microvasculature in the pathogenesis of dermatomyositis (DM). Our study evaluates whether standard…”
Get full text

Reverse fiber type disproportion: A distinct metabolic myopathy by Cooper, Christopher B., Dolezal, Brett A., Riley, Marshall, Verity, M. Anthony, Shieh, Perry B.

“…ABSTRACT Introduction In this investigation we characterized the physiological and metabolic responses to incremental exercise in 13 subjects with a…”
Get full text

Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscle by Kramerova, Irina, Kudryashova, Elena, Wu, Benjamin, Germain, Sean, Vandenborne, Krista, Romain, Nadine, Haller, Ronald G., Verity, M. Anthony, Spencer, Melissa J.

“…Mutations in the non-lysosomal cysteine protease calpain-3 cause autosomal recessive limb girdle muscular dystrophy. Pathological mechanisms occurring in this…”
Get full text

Clinical, pathological, and biochemical studies in a patient with propionic acidemia and fatal cardiomyopathy by Mardach, Rebecca, Verity, M. Anthony, Cederbaum, Stephen D.

“…A patient diagnosed at 9 months with a milder form of propionic acidemia was functioning at a near normal intellectual level and a normal neurological level at…”
Get full text

Oxidative mechanisms underlying methyl mercury neurotoxicity by Sarafian, T, Verity, M A

“…Cerebellar granule cells from 5-12-day-old rats can be incubated in suspension at 37 degrees C for up to 3 hr with minimal decline in viability. Methyl mercury…”
Get more information

Intact skeletal muscle mitochondrial enzyme activity but diminished exercise capacity in advanced heart failure patients on optimal medical and device therapy by Middlekauff, Holly R., Verity, M. Anthony, Horwich, Tamara B., Fonarow, Gregg C., Hamilton, Michele A., Shieh, Perry

“…Background A skeletal myopathy, perhaps attributable to neuro-endocrine excitation or disuse, has been described in heart failure (HF) patients, and is thought…”
Get full text

Myotoxic reactions to lipid-lowering therapy are associated with altered oxidation of fatty acids by Phillips, Paul S., Ciaraldi, Theodore P., Kim, Dong-Lim, Verity, M. Anthony, Wolfson, Tanya, Henry, Robert R.

“…Despite exceptional efficacy and safety, fear of muscle toxicity remains a major reason statins are underutilized. Evidence suggests that statin muscle…”
Get full text

Focal caspase activation underlies the endplate myopathy in slow-channel syndrome by Vohra, Bhupinder P. S., Groshong, Jason S., Maselli, Ricardo A., Verity, M. Anthony, Wollmann, Robert L., Gomez, Christopher M.

“…Slow‐channel syndrome (SCS) is a progressive neuromuscular disorder caused by abnormal gating of mutant acetylcholine receptors (AChRs) in the neuromuscular…”
Get full text

Differential expression of peroxiredoxin subtypes in human brain cell types by Sarafian, Theodore A., Verity, M. Anthony, Vinters, Harry V., Shih, Charles C.‐Y., Shi, Liangru, Ji, Xiang Dong, Dong, Lingpu, Shau, Hungyi

“…10.1002/(SICI)1097-4547(19990415)56:2<206::AID-JNR1>3.3.CO;2-OThe peroxiredoxin (Prx) protein is expressed widely in animal tissues and serves an antioxidant…”
Get full text

Differential expression of peroxiredoxin subtypes in human brain cell types by Sarafian, Theodore A., Verity, M. Anthony, Vinters, Harry V., Shih, Charles C.-Y., Shi, Liangru, Ji, Xiang Dong, Dong, Lingpu, Shau, Hungyi

“…The peroxiredoxin (Prx) protein is expressed widely in animal tissues and serves an antioxidant function associated with removal of cellular peroxides. We have…”
Get full text

Introduction: A Coming of Age for Molecular Neurotoxicology by Verity, M. Anthony

Get full text

Multiple Cerebral Pseudoaneurysms and Hemorrhages: The Expanding Spectrum of Metastatic Cerebral Choriocarcinoma by Kalafut, Mary, Vinuela, Fernando, Saver, Jeffrey L., Martin, Neil, Vespa, Paul, Verity, M. Anthony

“…Cerebral metastases occur in 10–20% of patients with choriocarcinoma. Although single oncotic and pseudoaneurysms have been reported, multiple pseudoaneurysms…”
Get full text

Modulation of intracellular cyclic adenosine monophosphate levels and the differentiation response of human neuroblastoma cells by Lando, M, Abemayor, E, Verity, M A, Sidell, N

“…We have tested the ability of various compounds to raise intracellular cyclic AMP (cAMP) levels and, either alone or in combination with retinoic acid (RA), to…”
Get full text

Lidocaine delays cortical ischemic depolarization: relationship to electrophysiologic recovery and neuropathology by Ayad, M, Verity, M A, Rubinstein, E H

“…To determine if the previously reported limitation of i.v. lidocaine in facilitating recovery from cerebral ischemia was related to an effect on ischemic…”
Get more information

Experimental methyl mercury neurotoxicity: locus of mercurial inhibition of brain protein synthesis in vivo and in vitro by Cheung, M K, Verity, M A

“…Brain cell-free protein synthesis is inhibited by methyl mercury chloride (MeHg) following in vivo or in vitro administration. In this report, we have…”
Get more information

Rapid cell death induced by methyl mercury in suspension of cerebellar granule neurons by Sarafian, T, Hagler, J, Vartavarian, L, Verity, M A

“…We have further investigated the cytotoxicity of methyl mercury (MeHg) in cerebellar granule neurons isolated from 5-12-day-old rats. At 20 microM MeHg…”
Get more information

Multiple sulfatase deficiency: clinical, neuropathological, ultrastructural and biochemical studies by Guerra, W F, Verity, M A, Fluharty, A L, Nguyen, H T, Philippart, M

“…We describe the clinical, pathological, ultrastructural and biochemical features in the case of a 15-year-old boy with multiple sulfatase deficiency. Clinical…”
Get more information