Search Results - "Verhoef, S"

Breast cancer risk after salpingo-oophorectomy in healthy BRCA1/2 mutation carriers: revisiting the evidence for risk reduction by Heemskerk-Gerritsen, B A M, Seynaeve, C, van Asperen, C J, Ausems, M G E M, Collée, J M, van Doorn, H C, Gomez Garcia, E B, Kets, C M, van Leeuwen, F E, Meijers-Heijboer, H E J, Mourits, M J E, van Os, T A M, Vasen, H F A, Verhoef, S, Rookus, M A, Hooning, M J

“…Previous studies have reported a breast cancer (BC) risk reduction of approximately 50% after risk-reducing salpingo-oophorectomy (RRSO) in BRCA1/2 mutation…”
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Validating measures of free-living physical activity in overweight and obese subjects using an accelerometer by Valenti, G, Camps, S G J A, Verhoef, S P M, Bonomi, A G, Westerterp, K R

“…Background: Free-living physical activity can be assessed with an accelerometer to estimate energy expenditure but its validity in overweight and obese…”
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Low prevalence of HER2 positivity amongst BRCA1 and BRCA2 mutation carriers and in primary BRCA screens by Evans, D. G., Lalloo, F., Howell, S., Verhoef, S., Woodward, E. R., Howell, A.

“…The aim of this study is to delineate more clearly the prevalence of HER2+ breast cancer in women with germline BRCA1/2 mutations. For this purpose, we…”
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Low-level constitutional mosaicism of BRCA1 in two women with young onset ovarian cancer by Speight, B., Colvin, E., Epurescu, E. D., Drummond, J., Verhoef, S., Pereira, M., Evans, D. G., Tischkowitz, M.

“…Abstract Germline pathogenic variants in BRCA1 and BRCA2 cause hereditary breast and ovarian cancer. The vast majority of these variants are inherited from a…”
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The relationship between leptin, gonadotropic hormones, and body composition during puberty in a Dutch children cohort by Rutters, F, Nieuwenhuizen, A G, Verhoef, S P M, Lemmens, S G T, Vogels, N, Westerterp-Plantenga, M S

“…ObjectiveTo investigate the relationship between leptin concentrations, gonadotropic hormone concentrations, and body composition during puberty in a Dutch…”
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A multiplex PCR predictor for aCGH success of FFPE samples by VAN BEERS, E. H, JOOSSE, S. A, LIGTENBERG, M. J, FLES, R, HOGERVORST, F. B. L, VERHOEF, S, NEDERLOF, P. M

“…Formalin-fixed, paraffin-embedded (FFPE) tissue archives are the largest and longest time-spanning collections of patient material in pathology archives…”
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CA125 and transvaginal ultrasound monitoring in high-risk women cannot prevent the diagnosis of advanced ovarian cancer by Olivier, R.I., Lubsen-Brandsma, M.A.C., Verhoef, S., van Beurden, M.

“…The main objective of screening is to identify cases of ovarian cancer in early stages. However, screening of women in the general population is ineffective…”
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Cancer risks in BRCA2 families: estimates for sites other than breast and ovary by van Asperen, C J, Brohet, R M, Meijers-Heijboer, E J, Hoogerbrugge, N, Verhoef, S, Vasen, H F A, Ausems, M G E M, Menko, F H, Gomez Garcia, E B, Klijn, J G M, Hogervorst, F B L, van Houwelingen, J C, van’t Veer, L J, Rookus, M A, van Leeuwen, F E

“…Background: In BRCA2 mutation carriers, increased risks have been reported for several cancer sites besides breast and ovary. As most of the families included…”
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A head-to-head comparison of conjugation methods for VHHs: Random maleimide-thiol coupling versus controlled click chemistry by van Moorsel, Marc V.A., Urbanus, Rolf T., Verhoef, S., Koekman, C.A., Vink, Maurice, Vermonden, T., Maas, Coen, Pasterkamp, Gerard, Schiffelers, Raymond M.

“…[Display omitted] Targeted delivery of therapeutics is an attractive strategy for vascular diseases. Recently, variable domains of heavy-chain-only antibodies…”
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Sleep duration and body-weight development during puberty in a Dutch children cohort by Rutters, F, Gerver, W.J, Nieuwenhuizen, A.G, Verhoef, S.P.M, Westerterp-Plantenga, M.S

“…Background: Short sleep duration is associated with obesity during childhood and adulthood. Objective: The objective of our study was to investigate the…”
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Platelet apoptosis by cold‐induced glycoprotein Ibα clustering by VAN DER WAL, D. E., DU, V. X., LO, K. S. L., RASMUSSEN, J. T., VERHOEF, S., AKKERMAN, J. W. N.

“…Background:  Cold‐storage of platelets followed by rewarming induces changes in Glycoprotein (GP) Ibα‐distribution indicative of receptor clustering and…”
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Multiplicity in polyp count and extracolonic manifestations in 40 Dutch patients with MYH associated polyposis coli (MAP) by Nielsen, M, Franken, P F, Reinards, T H C M, Weiss, M M, Wagner, A, van der Klift, H, Kloosterman, S, Houwing-Duistermaat, J J, Aalfs, C M, Ausems, M G E M, Bröcker-Vriends, A H J T, Gomez Garcia, E B, Hoogerbrugge, N, Menko, F H, Sijmons, R H, Verhoef, S, Kuipers, E J, Morreau, H, Breuning, M H, Tops, C M J, Wijnen, J T, Vasen, H F A, Fodde, R, Hes, F J

“…Objective: To investigate the contribution of MYH associated polyposis coli (MAP) among polyposis families in the Netherlands, and the prevalence of colonic…”
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Risk algorithms that include pathology adjustment for HER2 amplification need to make further downward adjustments in likelihood scores by Evans, D. G., Woodward, E. R., Howell, S. J., Verhoef, S., Howell, A., Lalloo, F.

“…To assess the need for adjustment in the likelihood of germline BRCA1/2 mutations in women with HER2+ breast cancers. We analysed primary mutation screens on…”
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Impact of rapid genetic counselling and testing on the decision to undergo immediate or delayed prophylactic mastectomy in newly diagnosed breast cancer patients: findings from a randomised controlled trial by Wevers, M R, Aaronson, N K, Verhoef, S, Bleiker, E M A, Hahn, D E E, Kuenen, M A, van der Sanden-Melis, J, Brouwer, T, Hogervorst, F B L, van der Luijt, R B, Valdimarsdottir, H B, van Dalen, T, Theunissen, E B M, van Ooijen, B, de Roos, M A, Borgstein, P J, Vrouenraets, B C, Vriens, E, Bouma, W H, Rijna, H, Vente, J P, Witkamp, A J, Rutgers, E J T, Ausems, M G E M

“…Background: Female breast cancer patients with a BRCA1/2 mutation have an increased risk of contralateral breast cancer. We investigated the effect of rapid…”
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Genetic structure in Orchesella cincta (Collembola): strong subdivision of European populations inferred from mtDNA and AFLP markers by Timmermans, M.J.T.N, Ellers, J, Marien, J, Verhoef, S.C, Ferwerda, E.B, Straalen, N.M. van

“…Population genetic structure is determined both by current processes and historical events. Current processes include gene flow, which is largely influenced by…”
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BRCA testing of breast cancer patients: medical specialists' referral patterns, knowledge and attitudes to genetic testing by VAN RIEL, E., WÁRLÁM-RODENHUIS, C.C., VERHOEF, S., RUTGERS, E.J.T.H., AUSEMS, M.G.E.M.

“…VAN RIEL E., WÁRLÁM‐RODENHUIS C.C., VERHOEF S., RUTGERS E.J.TH. & AUSEMS M.G.E.M. (2010) European Journal of Cancer Care19, 369–376
BRCA testing of breast…”
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Colorectal cancer risk variants at 8q23.3 and 11q23.1 are associated with disease phenotype in APC mutation carriers by Ghorbanoghli, Z., Nieuwenhuis, M. H., Houwing-Duistermaat, J. J., Jagmohan-Changur, S., Hes, F. J., Tops, C. M., Wagner, A., Aalfs, C. M., Verhoef, S., Gómez García, E. B., Sijmons, R. H., Menko, F. H., Letteboer, T. G., Hoogerbrugge, N., van Wezel, T., Vasen, H. F. A., Wijnen, J. T.

“…Familial adenomatous polyposis (FAP) is a dominantly inherited syndrome caused by germline mutations in the APC gene and characterized by the development of…”
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Regular surveillance for Li-fraumeni syndrome: advice, adherence and perceived benefits by Lammens, C. R. M., Bleiker, E. M. A., Aaronson, N. K., Wagner, A., Sijmons, R. H., Ausems, M. G. E. M., Vriends, A. H. J. T., Ruijs, M. W. G., van Os, T. A. M., Spruijt, L., Gómez García, E. B., Cats, A., Nagtegaal, T., Verhoef, S.

“…Li Fraumeni Syndrome (LFS) is a hereditary cancer syndrome characterized by a high risk of developing various types of cancer from birth through late…”
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Timing of risk reducing mastectomy in breast cancer patients carrying a BRCA1/2 mutation: retrospective data from the Dutch HEBON study by Wevers, M. R., Schmidt, M. K., Engelhardt, E. G., Verhoef, S., Hooning, M. J., Kriege, M., Seynaeve, C., Collée, M., van Asperen, C. J., Tollenaar, R. A. E. M., Koppert, L. B., Witkamp, A. J., Rutgers, E. J. T., Aaronson, N. K., Rookus, M. A., Ausems, M. G. E. M.

“…It is expected that rapid genetic counseling and testing (RGCT) will lead to increasing numbers of breast cancer (BC) patients knowing their BRCA1/2 carrier…”
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Distress in partners of individuals diagnosed with or at high risk of developing tumors due to rare hereditary cancer syndromes by Lammens, C. R. M., Bleiker, E. M. A., Verhoef, S., Ausems, M. G. E. M., Majoor-Krakauer, D., Sijmons, R. H., Hes, F. J., Gómez-García, E. B., Van Os, T. A. M., Spruijt, L., van der Luijt, R. B., van den Ouweland, A. M. W., Ruijs, M. W. G., Gundy, C., Nagtegaal, T., Aaronson, N. K.

“…Objective: Li Fraumeni syndrome (LFS) and Von Hippel‐Lindau disease (VHL) are two rare hereditary tumor syndromes, characterized by a high risk of developing…”
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