Search Results - "Verhoef, G E"

Non-invasive detection of genomic imbalances in Hodgkin/Reed-Sternberg cells in early and advanced stage Hodgkin's lymphoma by sequencing of circulating cell-free DNA: a technical proof-of-principle study by Vandenberghe, Peter, Prof, Wlodarska, Iwona, Prof, Tousseyn, Thomas, Prof, Dehaspe, Luc, PhD, Dierickx, Daan, Prof, Verheecke, Magali, MD, Uyttebroeck, Anne, Prof, Bechter, Oliver, Prof, Delforge, Michel, Prof, Vandecaveye, Vincent, Prof, Brison, Nathalie, PhD, Verhoef, Gregor EG, Prof, Legius, Eric, Prof, Amant, Frederic, Prof, Vermeesch, Joris R, Prof

“…Summary Background Hodgkin's lymphoma is one of the most common lymphoid neoplasms in young adults, but the low abundance of neoplastic Hodgkin/Reed-Sternberg…”
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Imatinib discontinuation in chronic phase myeloid leukaemia patients in sustained complete molecular response: A randomised trial of the Dutch–Belgian Cooperative Trial for Haemato-Oncology (HOVON) by Thielen, Noortje, van der Holt, Bronno, Cornelissen, Jan J, Verhoef, Gregor E.G, Gussinklo, Titia, Biemond, Bart J, Daenen, Simon M.G, Deenik, Wendy, van Marwijk Kooy, Rien, Petersen, Eefke, Smit, Willem M, Valk, Peter J.M, Ossenkoppele, Gert J, Janssen, Jeroen J.W.M

“…Abstract Background Tyrosine kinase inhibitors treatment in responding chronic myeloid leukaemia (CML) patients is generally continued indefinitely. In this…”
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Efficacy of escalated imatinib combined with cytarabine in newly diagnosed patients with chronic myeloid leukemia by DEENIK, Wendy, JANSSEN, Jeroen J. W. M, SONNEVELD, Pieter, VAN MARWIJK KOOY, Marinus, WITTEBOL, Shulamit, WILLEMZE, Roelof, WIJERMANS, Pierre W, BEVERLOO, H. Berna, LÖWENBERG, Bob, VALK, Peter J. M, OSSENKOPPELE, Gert J, CORNELISSEN, Jan J, VAN DER HOLT, Bronno, VERHOEF, Gregor E. G, SMIT, Willem M, KERSTEN, Marie José, DAENEN, Simon M. G. J, VERDONCK, Leo F, FERRANT, Augustin, SCHATTENBERG, Anton V. M. B

“…In order to improve the molecular response rate and prevent resistance to treatment, combination therapy with different dosages of imatinib and cytarabine was…”
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Myeloablative allogeneic versus autologous stem cell transplantation in adult patients with acute lymphoblastic leukemia in first remission: a prospective sibling donor versus no-donor comparison by Cornelissen, Jan J., van der Holt, Bronno, Verhoef, Gregor E.G., van 't Veer, Mars B., van Oers, Marinus H.J., Schouten, Harry C., Ossenkoppele, Gert, Sonneveld, Pieter, Maertens, Johan, van Marwijk Kooy, Marinus, Schaafsma, Martijn R., Wijermans, Pierre W., Biesma, Douwe H., Wittebol, Shulamit, Voogt, Paul J., Baars, Joke W., Zachée, Pierre, Verdonck, Leo F., Löwenberg, Bob, Dekker, Adriaan W.

“…While commonly accepted in poor-risk acute lymphoblastic leukemia (ALL), the role of allogeneic hematopoietic stem cell transplantation (allo-SCT) is still…”
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Addition of bevacizumab to chemotherapy in acute myeloid leukemia at older age: a randomized phase 2 trial of the Dutch-Belgian Cooperative Trial Group for Hemato-Oncology (HOVON) and the Swiss Group for Clinical Cancer Research (SAKK) by Ossenkoppele, Gert J., Stussi, Georg, Maertens, Johan, van Montfort, Kees, Biemond, Bart J., Breems, Dimitri, Ferrant, August, Graux, Carlos, de Greef, Georgine E., Halkes, C. J.M., Hoogendoorn, Mels, Hollestein, Rene M., Jongen-Lavrencic, Mojca, Levin, Mark D., van de Loosdrecht, Arjan A., van Marwijk Kooij, Marinus, van Norden, Yvette, Pabst, Thomas, Schouten, Harry C., Vellenga, Edo, Verhoef, Gregor E.G., de Weerdt, Okke, Wijermans, Pierre, Passweg, Jakob R., Löwenberg, Bob

“…An urgent need for new treatment modalities is emerging in elderly patients with acute myeloid leukemia (AML). We hypothesized that targeting VEGF might…”
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Physical Activity and Risk of Lymphoma: A Meta-Analysis by VERMAETE, Nele V. H, WOLTER, Pascal, VERHOEF, Gregor E. G, KOLLEN, Boudewijn J, KWAKKEL, Gert, SCHEPERS, Leen, GOSSELINK, Rik

“…Physical activity has a protective effect on some types of cancer. The aim of the present meta-analysis was to explore the literature on the association…”
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P-glycoprotein and Multidrug Resistance Protein Activities in Relation to Treatment Outcome in Acute Myeloid Leukemia by VAN DER KOLK, D. M, DE VRIES, E. G. E, VAN PUTTEN, W. L. J, VERDONCK, L. F, OSSENKOPPELE, G. J, VERHOEF, G. E. G, VELLENGA, E

“…Despite treatment with intensive chemotherapy, a considerable number of patients with acute myeloid leukemia (AML) die from their disease due to the occurrence…”
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Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia by Kim, Annette S, Schwartz, Marianne, Devriendt, Koenraad, Fryns, Jean-Pierre, Rosen, Michael K, Verhoef, Gregor E.G, Frints, Suzanna G.M, Van den Oord, Joost J, Vandenberghe, Peter, Mathijs, Gert, Boogaerts, Marc A, You, Daoqi

“…The Wiskott-Aldrich syndrome protein (WASP; encoded by the gene WAS) and its homologs are important regulators of the actin cytoskeleton, mediating…”
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Disseminated infection by Scedosporium prolificans : an emerging fatality among haematology patients. Case report and review by MAERTENS, J, LAGROU, K, DEWEERDT, H, SURMONT, I, VERHOEF, G. E. G, VERHAEGEN, J, BOOGAERTS, M. A

“…We describe a case of proven disseminated infection by Scedosporium prolificans in a profoundly neutropenic patient. The patient presented with a fever…”
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CD34-related coexpression of MDR1 and BCRP indicates a clinically resistant phenotype in patients with acute myeloid leukemia (AML) of older age by van den Heuvel-Eibrink, Marry M, van der Holt, Bronno, Burnett, Alan K, Knauf, Wolfgang U, Fey, Martin F, Verhoef, Gregor E G, Vellenga, Edo, Ossenkoppele, Gert J, Löwenberg, Bob, Sonneveld, Pieter

“…Clinical resistance to chemotherapy in acute myeloid leukemia (AML) is associated with the expression of the multidrug resistance (MDR) proteins…”
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Value of different modalities of granulocyte-macrophage colony-stimulating factor applied during or after induction therapy of acute myeloid leukemia by Löwenberg, B, Boogaerts, M A, Daenen, S M, Verhoef, G E, Hagenbeek, A, Vellenga, E, Ossenkoppele, G J, Huijgens, P C, Verdonck, L F, van der Lelie, J, Wielenga, J J, Schouten, H C, Gmür, J, Gratwohl, A, Hess, U, Fey, M F, van Putten, W L

“…The hematopoietic growth factors (HGFs) introduced into induction chemotherapy (CT) of acute myeloid leukemia (AML) might be of benefit to treatment outcome by…”
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High-vs low-dose cytarabine combined with interferon alfa in patients with first chronic phase chronic myeloid leukemia. A prospective randomized phase III study by Deenik, W, van der Holt, B, Verhoef, G E G, Schattenberg, A V M B, Verdonck, L F, Daenen, S M G J, Zachée, P, Westveer, P H M, Smit, W M, Wittebol, S, Schouten, H C, Löwenberg, B, Ossenkoppele, G J, Cornelissen, J J

“…A prospective randomized phase III study was performed to evaluate whether intensified cytarabine would induce a higher response rate and longer event-free…”
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Intensified 12-week CHOP (I-CHOP) plus G-CSF compared with standard 24-week CHOP (CHOP-21) for patients with intermediate-risk aggressive non-Hodgkin lymphoma: a phase 3 trial of the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) by Verdonck, Leo F., Notenboom, Annelise, de Jong, Daphne D., MacKenzie, Marius A., Verhoef, Gregor E.G., Kramer, Mark H.H., Ossenkoppele, Gert J., Doorduijn, Jeanette K., Sonneveld, Pieter, van Imhoff, Gustaaf W.

“…Optimal dose and timing of CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) chemotherapy for aggressive non-Hodgkin lymphoma (NHL) is still an…”
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Autologous bone marrow transplantation as consolidation therapy in the treatment of adult patients under 60 years with acute myeloid leukaemia in first complete remission: a prospective randomized Dutch–Belgian Haemato‐Oncology Co‐operative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK) trial by Breems, Dimitri A., Boogaerts, Marc A., Dekker, Adriaan W., Van Putten, Wim L. J., Sonneveld, Pieter, Huijgens, Peter C., Van der Lelie, Johannes, Vellenga, Edo, Gratwohl, Alois, Verhoef, Gregor E. G., Verdonck, Leo F., Löwenberg, Bob

“…Summary The question as to whether autologous stem cell transplantation (SCT) after consolidation chemotherapy improves the probability of survival of patients…”
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High-dose imatinib versus high-dose imatinib in combination with intermediate-dose cytarabine in patients with first chronic phase myeloid leukemia: a randomized phase III trial of the Dutch-Belgian HOVON study group by Thielen, Noortje, van der Holt, Bronno, Verhoef, Gregor E. G., Ammerlaan, Rianne A. H. M., Sonneveld, Pieter, Janssen, Jeroen J. W. M., Deenik, Wendy, Falkenburg, J. H. Frederik, Kersten, Marie José, Sinnige, Harm A. M., Schipperus, Martin, Schattenberg, Anton, van Marwijk Kooy, Rien, Smit, Willem M., Chu, Isabel W. T., Valk, Peter J. M., Ossenkoppele, Gert J., Cornelissen, Jan J.

“…Despite the revolutionary change in the prognosis of chronic myeloid leukemia (CML) patients with the introduction of imatinib, patients with resistant disease…”
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Feasibility of peripheral blood progenitor cell harvest and transplantation in patients with poor-risk myelodysplastic syndromes by Demuynck, H, Delforge, M, Verhoef, G E, Zachee, P, Vandenberghe, P, Van den Berghe, H, Boogaerts, M A

“…Myelodysplastic syndromes (MDS) are a group of clonal haematological disorders with a highly unfavourable prognosis. Allogeneic bone marrow transplantation…”
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Dose-finding study of imatinib in combination with intravenous cytarabine: feasibility in newly diagnosed patients with chronic myeloid leukemia by Deenik, Wendy, van der Holt, Bronno, Verhoef, Gregor E.G., Smit, Willem M., Kersten, Marie J., Kluin-Nelemans, Hanneke C., Verdonck, Leo F., Ferrant, Augustin, Schattenberg, Anton V. M.B., Janssen, Jeroen J. W.M., Sonneveld, Pieter, van Marwijk Kooy, Marinus, Wittebol, Shulamit, Willemze, Roelof, Wijermans, Pierre W., Westveer, Petra H.M., Beverloo, H. Berna, Valk, Peter, Löwenberg, Bob, Ossenkoppele, Gert J., Cornelissen, Jan J.

“…The HOVON cooperative study group performed a feasibility study of escalated imatinib and intravenous cytarabine in 165 patients with early chronic-phase…”
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Antifungal prophylaxis with itraconazole in prolonged neutropenia: correlation with plasma levels by Boogaerts, M A, Verhoef, G E, Zachee, P, Demuynck, H, Verbist, L, De Beule, K

“…Seventy-two patients with haematological malignancies were treated prophylactically with itraconazole during remission induction therapy. The incidence of…”
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Prognostic Index for Adult Patients With Acute Myeloid Leukemia in First Relapse by BREEMS, Dimitri A, VAN PUTTEN, Wim L. J, BOOGAERTS, Marc A, LÖWENBERG, Bob, HUIJGENS, Peter C, OSSENKOPPELE, Gert J, VERHOEF, Gregor E. G, VERDONCK, Leo F, VELLENGA, Edo, DE GREEF, Georgine E, JACKY, Emanuel, VAN DER LELIE, Johannes

“…The treatment of acute myeloid leukemia (AML) in first relapse is associated with unsatisfactory rates of complete responses that usually are short lived…”
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Case of megaloblastic anemia caused by intestinal taeniasis by Vuylsteke, Peter, Bertrand, Celine, Verhoef, Gregor E G, Vandenberghe, Peter

“…A 61-year-old eutrophic male was diagnosed with vitamin B12 deficiency and megaloblastic anemia. A modified Schilling test suggested intestinal malabsorption…”
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