Search Results - "Verheul, Marije"

Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis: Implications for Very Early Identification of At-Risk Individuals by Verheul, Marije K, Böhringer, Stefan, van Delft, Myrthe A M, Jones, Jonathan D, Rigby, William F C, Gan, Ryan W, Holers, V Michael, Edison, Jess D, Deane, Kevin D, Janssen, Koen M J, Westra, Johanna, Brink, Mikael, Rantapää-Dahlqvist, Solbritt, Huizinga, Tom W J, van der Helm-van Mil, Annette H M, van der Woude, Diane, Toes, Rene E M, Trouw, Leendert A

“…In rheumatoid arthritis (RA), anti-citrullinated protein antibodies (ACPAs) and rheumatoid factor (RF) are commonly used to aid in the diagnosis. Although…”
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Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage by Brink, Mikael, Verheul, Marije K, Rönnelid, Johan, Berglin, Ewa, Holmdahl, Rikard, Toes, Rene E M, Klareskog, Lars, Trouw, Leendert A, Rantapää-Dahlqvist, Solbritt

“…The presence of a new autoantibody system, anti-carbamylated protein (anti-CarP) antibodies, has been identified in rheumatoid arthritis (RA). The presence of…”
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Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis by Brink, Mikael, Hansson, Monika, Mathsson-Alm, Linda, Wijayatunga, Priyantha, Verheul, Marije K, Trouw, Leendert A, Holmdahl, Rikard, Rönnelid, Johan, Klareskog, Lars, Rantapää-Dahlqvist, Solbritt

“…The presence of rheumatoid factor (RF), anti-carbamylated protein antibodies (anti-CarP) and antibodies against citrullinated protein and peptides (ACPA)…”
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Identification of circulating monocytes as producers of tuberculosis disease biomarker C1q by Niewold, Paula, Dijkstra, Douwe J., Cai, Yi, Goletti, Delia, Palmieri, Fabrizio, van Meijgaarden, Krista E., Verreck, Frank A. W., Akkerman, Onno W., Hofland, Regina W., Delemarre, Eveline M., Nierkens, Stefan, Verheul, Marije K., Pollard, Andrew J., van Dissel, Jaap T., Ottenhoff, Tom H. M., Trouw, Leendert A., Joosten, Simone A.

“…Tuberculosis (TB) is a prevalent disease causing an estimated 1.6 million deaths and 10.6 million new cases annually. Discriminating TB disease from…”
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Repeated COVID-19 mRNA vaccination results in IgG4 class switching and decreased NK cell activation by S1-specific antibodies in older adults by Gelderloos, Anne T, Verheul, Marije K, Middelhof, Irene, de Zeeuw-Brouwer, Mary-Lène, van Binnendijk, Robert S, Buisman, Anne-Marie, van Kasteren, Puck B

“…Previous research has shown that repeated COVID-19 mRNA vaccination leads to a marked increase of SARS-CoV-2 spike-specific serum antibodies of the IgG4…”
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SARS-CoV-2 Spike S1-specific IgG kinetic profiles following mRNA or vector-based vaccination in the general Dutch population show distinct kinetics by van den Hoogen, Lotus L., Verheul, Marije K., Vos, Eric R. A., van Hagen, Cheyenne C. E., van Boven, Michiel, Wong, Denise, Wijmenga-Monsuur, Alienke J., Smits, Gaby, Kuijer, Marjan, van Rooijen, Debbie, Bogaard-van Maurik, Marjan, Zutt, Ilse, van Vliet, Jeffrey, Wolf, Janine, van der Klis, Fiona R. M., de Melker, Hester E., van Binnendijk, Robert S., den Hartog, Gerco

“…mRNA- and vector-based vaccines are used at a large scale to prevent COVID-19. We compared Spike S1-specific (S1) IgG antibodies after vaccination with…”
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Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register by Humphreys, Jennifer H, Verheul, Marije K, Barton, Anne, MacGregor, Alexander J, Lunt, Mark, Toes, Rene Em, Symmons, Deborah Pm, Trouw, Leendert A, Verstappen, Suzanne Mm

“…Anticarbamylated protein (anti-CarP) antibodies are a novel family of autoantibodies recently identified in patients with inflammatory arthritis. The aim of…”
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The risk of individual autoantibodies, autoantibody combinations and levels for arthritis development in clinically suspect arthralgia by Ten Brinck, Robin M, van Steenbergen, Hanna W, van Delft, Myrthe A M, Verheul, Marije K, Toes, Rene E M, Trouw, Leendert A, van der Helm-van Mil, Annette H M

“…Autoantibody testing is helpful for predicting the risk of progression to clinical arthritis in subjects at risk. Previous longitudinal studies have mainly…”
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Rheumatoid arthritis-associated autoantibodies in non-rheumatoid arthritis patients with mucosal inflammation: a case-control study by Janssen, Koen M J, de Smit, Menke J, Brouwer, Elisabeth, de Kok, Fenne A C, Kraan, Jan, Altenburg, Josje, Verheul, Marije K, Trouw, Leendert A, van Winkelhoff, Arie Jan, Vissink, Arjan, Westra, Johanna

“…Rheumatoid arthritis-associated autoantibodies (RA-AAB) can be present in serum years before clinical onset of rheumatoid arthritis (RA). It has been…”
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Contribution of SARS-CoV-2 infection preceding COVID-19 mRNA vaccination to generation of cellular and humoral immune responses in children by Verheul, Marije K, Vos, Martijn, de Rond, Lia, De Zeeuw-Brouwer, Mary-Lène, Nijhof, Kim H, Smit, Debbie, Oomen, Debbie, Molenaar, Petra, Bogaard, Marjan, van Bergen, Rianne, Middelhof, Irene, Beckers, Lisa, Wijmenga-Monsuur, Alienke J, Buisman, Anne-Marie, Boer, Mardi C, van Binnendijk, Rob, de Wit, Jelle, Guichelaar, Teun

“…Primary COVID-19 vaccination for children, 5-17 years of age, was offered in the Netherlands at a time when a substantial part of this population had already…”
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Identification of carbamylated alpha 1 anti-trypsin (A1AT) as an antigenic target of anti-CarP antibodies in patients with rheumatoid arthritis by Verheul, Marije K, Yee, Alvin, Seaman, Andrea, Janssen, George M, van Veelen, Peter A, Drijfhout, Jan W, Toes, Rene E.M, Mahler, Michael, Trouw, Leendert A

“…Abstract In 2011 a novel autoantibody system, anti-carbamylated protein (anti-CarP) antibodies, was described in rheumatoid arthritis (RA) patients. Anti-CarP…”
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Breach of autoreactive B cell tolerance by post-translationally modified proteins by Dekkers, Jacqueline S, Verheul, Marije K, Stoop, Jeroen N, Liu, Bisheng, Ioan-Facsinay, Andreea, van Veelen, Peter A, de Ru, Arnoud H, Janssen, George M C, Hegen, Martin, Rapecki, Steve, Huizinga, Tom W J, Trouw, Leendert A, Toes, René E M

“…Over 50% of patients with rheumatoid arthritis (RA) harbour a variety of anti-modified protein antibodies (AMPA) against different post-translationally…”
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Protective mucosal SARS-CoV-2 antibodies in the majority of the general population in the Netherlands by Verheul, Marije K., Kaczorowska, Joanna, Hofstee, Marloes I., Schepp, Rutger M., Smits, Gaby P., Wessels Beljaars, Dewi, Kuijer, Marjan, Schuin, Wendy, Middelhof, Irene, Wong, Denise, van Hagen, Cheyenne C.E., Vos, Eric R.A., Nicolaie, M. Alina, de Melker, Hester E., van Binnendijk, Robert S., van der Klis, Fiona R.M., den Hartog, Gerco

“…•The majority of the Dutch population (1–90 years of age) has parenteral and Omicron SARS-CoV-2–specific mucosal immunoglobulin (Ig)G antibodies.•The presence…”
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Anti-carbamylated protein antibodies precede disease onset in monkeys with collagen-induced arthritis by Verheul, Marije K, Vierboom, Michel P M, 't Hart, Bert A, Toes, Rene E M, Trouw, Leendert A

“…Rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA) and anti-carbamylated protein (anti-CarP) antibodies are rheumatoid arthritis…”
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The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients by van Delft, Myrthe A M, Verheul, Marije K, Burgers, Leonie E, Derksen, Veerle F A M, van der Helm-van Mil, Annette H M, van der Woude, Diane, Huizinga, Tom W J, Toes, René E M, Trouw, Leendert A

“…Anti-carbamylated protein (anti-CarP) antibodies have recently been reported to occur in around 45% of rheumatoid arthritis (RA) patients and to have…”
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Vi-Vaccinations Induce Heterogeneous Plasma Cell Responses That Associate With Protection From Typhoid Fever by Cross, Deborah L, Verheul, Marije K, Leipold, Michael D, Obermoser, Gerlinde, Jin, Celina, Jones, Elizabeth, Starr, Joshua S, Mohorianu, Irina, Blohmke, Christoph J, Maecker, Holden T, Napolitani, Giorgio, Hill, Jennifer, Pollard, Andrew J

“…Vi-polysaccharide conjugate vaccines are efficacious against cases of typhoid fever; however, an absolute correlate of protection is not established. In this…”
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Booster Immunization Improves Memory B Cell Responses in Older Adults Unresponsive to Primary SARS-CoV-2 Immunization by Verheul, Marije K, Nijhof, Kim H, de Zeeuw-Brouwer, Mary-Lène, Duijm, Geraly, Ten Hulscher, Hinke, de Rond, Lia, Beckers, Lisa, Eggink, Dirk, van Tol, Sophie, Reimerink, Johan, Boer, Mardi, van Beek, Josine, Rots, Nynke, van Binnendijk, Rob, Buisman, Anne-Marie

“…The generation of a specific long-term immune response to SARS-CoV-2 is considered important for protection against COVID-19 infection and disease. Memory B…”
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Accelerating clinical development of a live attenuated vaccine against Salmonella Paratyphi A (VASP): study protocol for an observer-participant-blind randomised control trial of a novel oral vaccine using a human challenge model of Salmonella Paratyphi A infection in healthy adult volunteers by McCann, Naina, Emary, Katherine, Singh, Nisha, Mclean, Florence, Camara, Susana, Jones, Elizabeth, Kim, Young Chan, Liu, Xinxue, Greenland, Melanie, Conlin, Kerry, Hill, Jennifer, Verheul, Marije, Robinson, Hannah, Angus, Brian, Ramasamy, Maheshi N, Levine, Myron M, Pollard, Andrew J

“…IntroductionThis is the first efficacy study of an oral live attenuated vaccine against Salmonella Paratyphi A using a human challenge model of paratyphoid…”
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Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent by Verheul, Marije K, Shiozawa, Kazuko, Levarht, E W Nivine, Huizinga, Tom W J, Toes, Rene E M, Trouw, Leendert A, Shiozawa, Shunichi

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The anti-carbamylated protein antibody response is of overall low avidity despite extensive isotype switching by van Delft, Myrthe A M, Verheul, Marije K, Burgers, Leonie E, Rantapää-Dahlqvist, Solbritt, van der Helm-van Mil, Annette H M, Huizinga, Tom W J, Toes, René E M, Trouw, Leendert A

“…Abstract Objective To better understand the contribution of autoantibodies in RA and the biology of their responses, we evaluated the avidity of the…”
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