Search Results - "Verhein, Kirsten C"

Dual p38/JNK mitogen activated protein kinase inhibitors prevent ozone-induced airway hyperreactivity in guinea pigs by Verhein, Kirsten C, Salituro, Francesco G, Ledeboer, Mark W, Fryer, Allison D, Jacoby, David B

“…Ozone exposure causes airway hyperreactivity and increases hospitalizations resulting from pulmonary complications. Ozone reacts with the epithelial lining…”
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Determinants of host susceptibility to murine respiratory syncytial virus (RSV) disease identify a role for the innate immunity scavenger receptor MARCO gene in human infants by High, Monica, Cho, Hye-Youn, Marzec, Jacqui, Wiltshire, Tim, Verhein, Kirsten C., Caballero, Mauricio T., Acosta, Patricio L., Ciencewicki, Jonathan, McCaw, Zackary R., Kobzik, Lester, Miller-DeGraff, Laura, Gladwell, Wes, Peden, David B., Serra, M. Elina, Shi, Min, Weinberg, Clarice, Suzuki, Oscar, Wang, Xuting, Bell, Douglas A., Polack, Fernando P., Kleeberger, Steven R.

“…Respiratory syncytial virus (RSV) is the global leading cause of lower respiratory tract infection in infants. Nearly 30% of all infected infants develop…”
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Inter-individual variation in health and disease associated with pulmonary infectious agents by Verhein, Kirsten C., Vellers, Heather L., Kleeberger, Steven R.

“…Respiratory infectious diseases resulting from bacterial or viral pathogens such as Mycobacterium tuberculosis, Streptococcus pneumoniae , respiratory…”
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Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice by Verhein, Kirsten C, McCaw, Zachary, Gladwell, Wesley, Trivedi, Shweta, Bushel, Pierre R, Kleeberger, Steven R

“…Ozone is a highly toxic air pollutant and global health concern. Mechanisms of genetic susceptibility to ozone-induced lung inflammation are not completely…”
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Association between Mitochondrial DNA Sequence Variants and V˙O2 max Trainability by VELLERS, HEATHER L., VERHEIN, KIRSTEN C., BURKHOLDER, ADAM B., LEE, JAEHOON, KIM, YOUNGMIN, LIGHTFOOT, J. TIMOTHY, SHI, MIN, WEINBERG, CLARICE R., SARZYNSKI, MARK A., BOUCHARD, CLAUDE, KLEEBERGER, STEVEN R.

“…PURPOSEWe designed the study to determine whether mitochondrial DNA (mtDNA) haplogroup, sequence, and heteroplasmy differed between individuals previously…”
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Multi-walled carbon nanotubes upregulate mitochondrial gene expression and trigger mitochondrial dysfunction in primary human bronchial epithelial cells by Snyder, Ryan J., Verhein, Kirsten C., Vellers, Heather L., Burkholder, Adam B., Garantziotis, Stavros, Kleeberger, Steven R.

“…Nanomaterials are a relatively new class of materials that acquire novel properties based on their reduced size. While these materials have widespread use in…”
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Effects of mannose-binding lectin on pulmonary gene expression and innate immune inflammatory response to ozone by Ciencewicki, Jonathan M, Verhein, Kirsten C, Gerrish, Kevin, McCaw, Zachary R, Li, Jianying, Bushel, Pierre R, Kleeberger, Steven R

“…Ozone is a common, potent oxidant pollutant in industrialized nations. Ozone exposure causes airway hyperreactivity, lung hyperpermeability, inflammation, and…”
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Genome‐wide association mapping of acute lung injury in neonatal inbred mice by Nichols, Jennifer L., Gladwell, Wesley, Verhein, Kirsten C., Cho, Hye‐Youn, Wess, Jürgen, Suzuki, Oscar, Wiltshire, Tim, Kleeberger, Steven R.

“…ABSTRACT Reactive oxygen species (ROS) contribute to the pathogenesis of many acute and chronic pulmonary disorders, including bronchopulmonary dysplasia…”
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IL-1 Receptors Mediate Persistent, but Not Acute, Airway Hyperreactivity to Ozone in Guinea Pigs by Verhein, Kirsten C, Jacoby, David B, Fryer, Allison D

“…Ozone exposure in the lab and environment causes airway hyperreactivity lasting at least 3 days in humans and animals. In guinea pigs 1 day after ozone…”
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Neural control of airway inflammation by Verhein, Kirsten C., Fryer, Allison D., Jacoby, David B.

“…Abnormal neural function contributes to the pathogenesis of airway disease. In addition to affecting airway physiology, the nerves produce and release…”
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Three days after a single exposure to ozone, the mechanism of airway hyperreactivity is dependent on substance P and nerve growth factor by Verhein, Kirsten C, Hazari, Mehdi S, Moulton, Bart C, Jacoby, Isabella W, Jacoby, David B, Fryer, Allison D

“…Ozone causes persistent airway hyperreactivity in humans and animals. One day after ozone exposure, airway hyperreactivity is mediated by release of eosinophil…”
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Abstract 3114: Analytical validation of Illumina's TruSight Oncology 500 ctDNA assay by Verhein, Kirsten C., Hariani, Gunjan, Hastings, Stephanie B., Hurban, Patrick

“…Abstract While tissue biopsies and imaging techniques remain the current standard of care, minimally invasive liquid biopsy tests are emerging as compelling…”
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Association between Mitochondrial DNA Sequence Variants and VO2 max Trainability by Vellers, Heather L., Verhein, Kirsten C., Burkholder, Adam B., Lee, Jaehoon, Kim, Youngmin, Lightfoot, J. Timothy, Shi, Min, Weinberg, Clarice R., Sarzynski, Mark A., Bouchard, Claude, Kleeberger, Steven R.

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Association Between Mitochondrial Dna Sequence, Heteroplasmy, And Indels With Response To Aerobic Exercise Training: 2109 Board #265 May 30 3:30 PM - 5:00 PM by Vellers, Heather L., Verhein, Kirsten C., Kleeberger, Steven R., Burkholder, Adam B., Lightfoot, Timothy J., Marzec, Jacqui, Bouchard, Claude

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Inter‐Strain Variation in Mouse Mitochondrial Genome and Effects of Oxidative Stress by Verhein, Kirsten C, Burkholder, Adam, Nichols, Jennifer L, McCaw, Zachary, Marzec, Jacqui, Panduri, Vijayalakshmi, Gladwell, Wesley, Reeves, Nicole, Malphurs, Jason, Solomon, Greg, Wiltshire, Tim, Fargo, David, Bell, Douglas, Van Houten, Bennett, Kleeberger, Steven R

“…Abstract only Reactive oxygen species contribute to the pathogenesis of many acute and chronic pulmonary disorders, including bronchopulmonary dysplasia (BPD),…”
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409 - Genetic Determinants of Oxidant-Induced Nuclear and Mitochondrial DNA Lesions in a Neonatal Inbred Mouse Model of Acute Lung Injury by Verhein, Kirsten C, Nichols, Jennifer L, Panduri, Vijayalakshmi, Gladwell, Wesley, Marzec, Jacqui, McCaw, Zachary, Reeves, Nicole, Malphurs, Jason, Solomon, Greg, Wiltshire, Tim, Burkholder, Adam, Fargo, David, Bell, Douglas, Van Houten, Bennett, Kleeberger, Steven R

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Genetic Determinants of Oxidant-Induced Nuclear and Mitochondrial DNA Lesions in a Neonatal Inbred Mouse Model of Acute Lung Injury by Verhein, Kirsten C, Nichols, Jennifer L, Panduri, Vijayalakshmi, Gladwell, Wesley, Marzec, Jacqui, McCaw, Zachary, Reeves, Nicole, Malphurs, Jason, Solomon, Greg, Wiltshire, Tim, Burkholder, Adam, Fargo, David, Bell, Douglas, Van Houten, Bennett, Kleeberger, Steven R

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Identification of candidate susceptibility genes in a murine model of respiratory syncytial virus (RSV)‐induced bronchiolitis by Verhein, Kirsten C, High, Monica, Marzec, Jacqui, McCaw, Zachary, Wiltshire, Tim, Chen, Yu, Burkholder, Adam, Klimczak, Les, Fargo, David, Kleeberger, Steven R

“…Abstract only RSV is the most common cause of serious lower respiratory illnesses in infants and children. While genetic association studies have been reported…”
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Dual p38/JNK Mitogen Activated Protein Kinase Inhibitors Prevent Ozone-Induced Airway Hyperreactivity in Guinea Pigs: e75351 by Verhein, Kirsten C, Salituro, Francesco G, Ledeboer, Mark W, Fryer, Allison D, Jacoby, David B

“…Ozone exposure causes airway hyperreactivity and increases hospitalizations resulting from pulmonary complications. Ozone reacts with the epithelial lining…”
Get full text