Search Results - "Verhaert, Peter"

High-throughput isotherm determination and thermodynamic modeling of protein adsorption on mixed mode adsorbents by Nfor, Beckley K., Noverraz, Marc, Chilamkurthi, Sreekanth, Verhaert, Peter D.E.M., van der Wielen, Luuk A.M., Ottens, Marcel

“…The thermodynamic modeling of protein adsorption on mixed-mode adsorbents functionalized with ligands carrying both hydrophobic and electrostatic groups was…”
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Digestion-Free Analysis of Peptides from 30-year-old Formalin-Fixed, Paraffin-Embedded Tissue by Mass Spectrometry Imaging by Paine, Martin R. L, Ellis, Shane R, Maloney, Dan, Heeren, Ron M. A, Verhaert, Peter D. E. M

“…Formalin-fixed neuroendocrine tissues from American cockroaches (Periplaneta americana) embedded in paraffin more than 30 years ago were recently analyzed by…”
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The Bright Future of Peptidomics by Verhaert, Peter D E M

“…In this final chapter I project my personal perspective on the future of peptidomics. A bird's eye view is shed on the discipline and a bid is made to frame it…”
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The 33rd International Tandem Mass Spectrometry Workshop, Lake Louise, Alberta, Canada by Konermann, Lars, Amster, I. Jonathan, Smith, Jeffrey C, Verhaert, Peter D. E. M

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Hippocampal neuropathology in suicide: Gaps in our knowledge and opportunities for a breakthrough by Zhang, Lin, Lucassen, Paul J., Salta, Evgenia, Verhaert, Peter D.E.M., Swaab, Dick F.

“…•Suicidality may have putative psychopathological alterations in the hippocampus.•Hippocampus-targeted cognitive improvement is key to suicide…”
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Spatially Resolved Neuropeptide Characterization from Neuropathological Formalin-Fixed, Paraffin-Embedded Tissue Sections by a Combination of Imaging MALDI FT-ICR Mass Spectrometry Histochemistry and Liquid Extraction Surface Analysis-Trapped Ion Mobility Spectrometry-Tandem Mass Spectrometry by Cintron-Diaz, Yarixa L, Gomez-Hernandez, Mario E, Verhaert, Marthe M. H. A, Verhaert, Peter D. E. M, Fernandez-Lima, Francisco

“…To make the vast collections of well-documented human clinical samples archived in biobanks accessible for mass spectrometry imaging (MSI), recent developments…”
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The deep-subsurface sulfate reducer Desulfotomaculum kuznetsovii employs two methanol-degrading pathways by Sousa, Diana Zita Machado, Visser, Michael, van Gelder, Antonie H., Boeren, Sjef, Pieterse, Mervin M., Pinkse, Martijn W. H., Verhaert, Peter D. E. M., Vogt, Carsten, Franke, Steffi, Kümmel,Steffen, Stams, Alfons Johannes Maria

“…Methanol is generally metabolized through a pathway initiated by a cobalamine-containing methanol methyltransferase by anaerobic methylotrophs (such as…”
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Accelerating the search for the missing proteins in the human proteome by Baker, Mark S., Ahn, Seong Beom, Mohamedali, Abidali, Islam, Mohammad T., Cantor, David, Verhaert, Peter D., Fanayan, Susan, Sharma, Samridhi, Nice, Edouard C., Connor, Mark, Ranganathan, Shoba

“…The Human Proteome Project (HPP) aims to discover high-stringency data for all proteins encoded by the human genome. Currently, ∼18% of the proteins in the…”
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Rational and systematic protein purification process development: the next generation by Nfor, Beckley K, Verhaert, Peter D.E.M, van der Wielen, Luuk A.M, Hubbuch, Jürgen, Ottens, Marcel

“…Current biopharmaceutical manufacturing strongly relies on using purification platform processes, offering harmonization of practices and speed-to-market…”
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High throughput techniques to reveal the molecular physiology and evolution of digestion in spiders by Fuzita, Felipe J, Pinkse, Martijn W H, Patane, José S L, Verhaert, Peter D E M, Lopes, Adriana R

“…Spiders are known for their predatory efficiency and for their high capacity of digesting relatively large prey. They do this by combining both extracorporeal…”
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The emergence of peptides in the pharmaceutical business: From exploration to exploitation by Uhlig, Thomas, Kyprianou, Themis, Martinelli, Filippo Giancarlo, Oppici, Carlo Alberto, Heiligers, Dave, Hills, Diederik, Calvo, Xavier Ribes, Verhaert, Peter

“…•An overview is presented how peptides face the various steps in drug development.•Previously considered troublesome drug candidates, peptides now get to the…”
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Analytical characterization of complex, biotechnological feedstocks by pH gradient ion exchange chromatography for purification process development by Kröner, Frieder, Hanke, Alexander T., Nfor, Beckley K., Pinkse, Martijn W.H., Verhaert, Peter D.E.M., Ottens, Marcel, Hubbuch, Jürgen

“…•Multidimensional analysis to characterize complex biotechnological feedstocks.•pH gradient IEC is used to fractionate a lysate containing a diagnostic…”
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Unravelling the one-carbon metabolism of the acetogen Sporomusa strain An4 by genome and proteome analysis by Visser, Michael, Pieterse, Mervin M., Pinkse, Martijn W. H., Nijsse, Bart, Verhaert, Peter D. E. M., de Vos, Willem M., Schaap, Peter J., Stams, Alfons J. M.

“…The Sporomusa genus comprises anaerobic spore-forming acetogenic bacteria that stain Gram-negative. Sporomusa species typically grow with one-carbon substrates…”
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Biochemical, transcriptomic and proteomic analyses of digestion in the scorpion Tityus serrulatus: insights into function and evolution of digestion in an ancient arthropod by Fuzita, Felipe J, Pinkse, Martijn W H, Patane, José S L, Juliano, Maria A, Verhaert, Peter D E M, Lopes, Adriana R

“…Scorpions are among the oldest terrestrial arthropods and they have passed through small morphological changes during their evolutionary history on land. They…”
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Oleate Hydratase Catalyzes the Hydration of a Nonactivated Carbon-Carbon Bond by BEVERS, Loes E, PINKSE, Martijn W. H, VERHAERT, Peter D. E. M, HAGEN, Wilfred R

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Prediction of protein retention times in hydrophobic interaction chromatography by robust statistical characterization of their atomic-level surface properties by Hanke, Alexander T., Klijn, Marieke E., Verhaert, Peter D. E. M., van der Wielen, Luuk A. M., Ottens, Marcel, Eppink, Michel H. M., van de Sandt, Emile J. A. X.

“…The correlation between the dimensionless retention times (DRT) of proteins in hydrophobic interaction chromatography (HIC) and their surface properties were…”
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Sample Preparation Techniques for the Untargeted LC-MS-Based Discovery of Peptides in Complex Biological Matrices by Verhaert, Peter D. E. M., Van Dongen, William, Pinkse, Martijn W. H., Finoulst, Inez

“…Although big progress has been made in sample pretreatment over the last years, there are still considerable limitations when it comes to overcoming complexity…”
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High-throughput protein precipitation and hydrophobic interaction chromatography: Salt effects and thermodynamic interrelation by Nfor, Beckley K., Hylkema, Nienke N., Wiedhaup, Koenraad R., Verhaert, Peter D.E.M., van der Wielen, Luuk A.M., Ottens, Marcel

“…Salt-induced protein precipitation and hydrophobic interaction chromatography (HIC) are two widely used methods for protein purification. In this study, salt…”
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3D-liquid chromatography as a complex mixture characterization tool for knowledge-based downstream process development by Hanke, Alexander T., Tsintavi, Eleni, Ramirez Vazquez, Maria del Pilar, van der Wielen, Luuk A. M., Verhaert, Peter D. E. M., Eppink, Michel H. M., van de Sandt, Emile J. A. X., Ottens, Marcel

“…Knowledge‐based development of chromatographic separation processes requires efficient techniques to determine the physicochemical properties of the product…”
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High-Accuracy Mass Spectrometry Based Screening Method for the Discovery of Cysteine Containing Peptides in Animal Venoms and Toxins by van Oosten, Luuk N, Pinkse, Martijn W H, Pieterse, Mervin, Escoubas, Pierre, Verhaert, Peter D E M

“…Venom and toxin samples derived from animal origins are a rich source of bioactive peptides. A high proportion of bioactive peptides that have been identified…”
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