Search Results - "Vergo, Sandra"

Modelling a Human Blood-Brain Barrier Co-Culture Using an Ultrathin Silicon Nitride Membrane-Based Microfluidic Device by Hudecz, Diana, McCloskey, Molly C, Vergo, Sandra, Christensen, Søren, McGrath, James L, Nielsen, Morten S

“…Understanding the vesicular trafficking of receptors and receptor ligands in the brain capillary endothelium is essential for the development of the next…”
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Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system by Friese, Manuel A, Etzensperger, Ruth, Craner, Matthew J, Wemmie, John A, Welsh, Michael J, Fugger, Lars, Vergo, Sandra, Vincent, Angela

“…Multiple sclerosis is a neuroinflammatory disease associated with axonal degeneration. The neuronally expressed, proton-gated acid-sensing ion channel-1…”
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Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model by VERGO, Sandra, CRANER, Matthew J, ETZENSPERGER, Ruth, ATTFIELD, Kathrine, FRIESE, Manuel A, NEWCOMBE, Jia, ESIRI, Margaret, FUGGER, Lars

“…Although there is growing evidence for a role of excess intracellular cations, particularly calcium ions, in neuronal and glial cell injury in multiple…”
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Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels by Vergo, Sandra, Johansen, Jens Leander, Leist, Marcel, Lotharius, Julie

“…Abstract An abnormal accumulation of cytosolic dopamine resulting in reactive oxygen species and dopamine–quinone products may play an important role in the…”
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Evaluating IL-21 as a Potential Therapeutic Target in Crohn’s Disease by Frederiksen, Klaus Stensgaard, Haase, Claus, Lundsgaard, Dorthe, Holgersen, Kristine, Hermit, Mette Brunsgaard, Hansen, Lene, Sondergaard, Bodil-Cecilie, Kvist, Peter H., Søndergaard, Henrik, Tornehave, Ditte, Lindebo Holm, Thomas, Vergo, Sandra

“…Background and Aim. Interleukin-21 (IL-21) is primarily a T cell-derived cytokine; it is upregulated in patients with Crohn’s Disease (CD) and could be a…”
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Regulation of Gephyrin Assembly and Glycine Receptor Synaptic Stability by Bedet, Cécile, Bruusgaard, Jo C., Vergo, Sandra, Groth-Pedersen, Line, Eimer, Stefan, Triller, Antoine, Vannier, Christian

“…Gephyrin is required for the formation of clusters of the glycine receptor (GlyR) in the neuronal postsynaptic membrane. It can make trimers and dimers through…”
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Brain‐Wide Monitoring of Antibody Therapeutics Crossing the Blood‐Brain‐Barrier by Redd, Chase, Guanzon, Nathaniel, Gallegos, Yessenia, Weiss, Jacob, Jensen, Camilla Stampe, Vergo, Sandra B., Wheeler, Damian G.

“…Background Recent advances in optical clearing and light sheet imaging have opened an exciting new avenue for brain‐wide, cellular resolution immunostaining at…”
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Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride by ARUN, Tarunya, TOMASSINI, Valentina, FUGGER, Lars, ROVIRA, Alex, JENKINSON, Mark, PALACE, Jacqueline, SBARDELLA, Emilia, DE RUITER, Michiel B, MATTHEWS, Lucy, ISABEL LEITE, Maria, GELINEAU-MOREL, Rose, CAVEY, Ana, VERGO, Sandra, CRANER, Matt

“…Neurodegeneration is the main cause for permanent disability in multiple sclerosis. The effect of current immunomodulatory treatments on neurodegeneration is…”
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Visualization of brain targets with 89 Zr‐immuno‐PET using a novel bispecific amyloid ß monoclonal antibody by Stergiou, Natascha, Wünsche, Thomas, Mes, Iris, Schreurs, Maxime, Verlaan, Mariska, Kooijman, Esther, Windhorst, Albert D., Dongen, Guus AMS, Helboe, Lone, Vergo, Sandra, Christensen, Søren, Asuni, Ayodeji A, Jensen, Allan, Bang‐Andersen, Benny, Vugts, Danielle, Beaino, Wissam

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Visualization of brain targets with 89Zr‐immuno‐PET using a novel bispecific amyloid ß monoclonal antibody by Stergiou, Natascha, Wünsche, Thomas, Mes, Iris, Schreurs, Maxime, Verlaan, Mariska, Kooijman, Esther, Windhorst, Albert D., Dongen, Guus AMS, Helboe, Lone, Vergo, Sandra, Christensen, Søren, Asuni, Ayodeji A, Jensen, Allan, Bang‐Andersen, Benny, Vugts, Danielle, Beaino, Wissam

“…Background Recent preclinical and clinical studies in the diagnosis and treatment of Alzheimer Disease (AD) focus on antibody based radioligands and…”
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SSP-27 - 89Zr-immuno-PET of a novel bispecific amyloid-β monoclonal antibody reveals improved and high specific brain uptake by Stergiou, Natascha, Wünsche, Thomas, Mes, Iris, Schreurs, Maxime, Verlaan, Mariska, Kooijman, Esther, Windhorst, Albert, van Dongen, Guus, Helboe, Lone, Vergo, Sandra, Christensen, Soren, Asuni, Ayodeji, Jensen, Allan, Bang-Andersen, Benny, Vugts, Danielle, Beaino, Wissam

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89Zr-immuno-PET of a novel bispecific amyloid-β monoclonal antibody reveals improved and high specific brain uptake by Stergiou, Natascha, Wünsche, Thomas, Mes, Iris, Schreurs, Maxime, Verlaan, Mariska, Kooijman, Esther, Windhorst, Albert, van Dongen, Guus, Helboe, Lone, Vergo, Sandra, Christensen, Soren, Asuni, Ayodeji, Jensen, Allan, Bang-Andersen, Benny, Vugts, Danielle, Beaino, Wissam

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