Search Results - "Vergnet, Nicolas"
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Longitudinal atrophy in early Braak regions in preclinical Alzheimer's disease
Published in Human brain mapping (01-11-2020)“…A major focus of Alzheimer's disease (AD) research has been finding sensitive outcome measures to disease progression in preclinical AD, as intervention…”
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In vivo measures of tau burden are associated with atrophy in early Braak stage medial temporal lobe regions in amyloid-negative individuals
Published in Alzheimer's & dementia (01-10-2019)“…It is unclear the degree to which tau pathology in the medial temporal lobe (MTL) measured by 18F-flortaucipir positron emission tomography relates to MTL…”
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Subtle differences in the appearance of hippocampal layers differentiate preclinical AD from healthy aging
Published in Alzheimer's & dementia (01-12-2020)“…Background Degeneration of the stratum radiatum lacunosum moleculare (SRLM), located between the cornu ammonis (CA)/subiculum and dentate gyrus (DG) subfields…”
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Application of histopathologically derived 3D tau burden map as in‐vivo region of interest for biomarker analysis
Published in Alzheimer's & dementia (01-12-2021)“…Background Quantitative three‐dimensional maps of tau neurofibrillary tangles (NFT) burden derived from dense serial histology have potential application for…”
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Journal Article -
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3D Mapping of TAU Neurofibrillary Tangle Pathology in the Human Medial Temporal Lobe
Published in 2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI) (01-04-2020)“…Tau protein neurofibrillary tangles (NFT) are linked to neuronal and synaptic loss and cognitive decline in Alzheimer's disease (AD) and related dementias. In…”
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Conference Proceeding