Search Results - "Verges, Marcel"

Retromer in Polarized Protein Transport by Vergés, Marcel

“…Retromer is an evolutionary conserved protein complex required for endosome-to-Golgi retrieval of receptors for lysosomal hydrolases. It is constituted by a…”
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Trafficking and Function of the Voltage-Gated Sodium Channel β2 Subunit by Cortada, Eric, Brugada, Ramon, Verges, Marcel

“…The voltage-gated sodium channel is vital for cardiomyocyte function, and consists of a protein complex containing a pore-forming α subunit and two associated…”
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Retromer: Multipurpose Sorting and Specialization in Polarized Transport by Vergés, Marcel

“…Retromer is an evolutionary conserved protein complex required for endosome-to-Golgi retrieval of lysosomal hydrolases' receptors. A dimer of two sorting…”
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A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor by Mostov, Keith E, Su, Tao, Bryant, David M, Luton, Frédéric, Vergés, Marcel, Ulrich, Scott M, Hansen, Kirk C, Datta, Anirban, Eastburn, Dennis J, Burlingame, Alma L, Shokat, Kevan M

“…Epithelial cell transcytosis of polymeric IgA by its receptor requires polarized membrane trafficking. A signalling cascade involving the tyrosine kinase YES,…”
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Role of protein domains in trafficking and localization of the voltage-gated sodium channel β2 subunit by Cortada, Eric, Brugada, Ramon, Verges, Marcel

“…The voltage-gated sodium (NaV) channel is critical for cardiomyocyte function since it is responsible for action potential initiation and its propagation…”
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NaV1.5 in embryonic heart development by Cortada, Eric, Verges, Marcel

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Na V 1.5 in embryonic heart development by Cortada, Eric, Verges, Marcel

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Alterations in ubiquitin‐mediated degradation of NaV1.5 can cause arrhythmia by Cortada, Eric, Verges, Marcel

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Alterations in ubiquitin-mediated degradation of Na V 1.5 can cause arrhythmia by Cortada, Eric, Verges, Marcel

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N-Glycosylation of the voltage-gated sodium channel β2 subunit is required for efficient trafficking of NaV1.5/β2 to the plasma membrane by Cortada, Eric, Brugada, Ramon, Verges, Marcel

“…The voltage-gated sodium channel is critical for cardiomyocyte function and consists of a protein complex comprising a pore-forming α subunit and two…”
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The voltage-gated sodium channel β2 subunit associates with lipid rafts by S-palmitoylation by Cortada, Eric, Serradesanferm, Robert, Brugada, Ramon, Verges, Marcel

“…The voltage-gated sodium channel is critical for cardiomyocyte function. It consists of a protein complex comprising a pore-forming α subunit and associated β…”
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NaV 1.5 in embryonic heart development by Cortada, Eric, Verges, Marcel

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Alterations in ubiquitin-mediated degradation of NaV 1.5 can cause arrhythmia by Cortada, Eric, Verges, Marcel

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Retromer and sorting nexins in development by Verges, Marcel

“…Trafficking and signaling processes involve common molecular components. The machinery that controls intracellular trafficking is vital in ensuring that…”
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The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor by Mostov, Keith E, Vergés, Marcel, Luton, Frédéric, Gruber, Carmen, Tiemann, Frank, Reinders, Lorri G, Huang, Lan, Burlingame, Alma L, Haft, Carol R

“…Epithelial cells have separate apical and basolateral plasma membrane domains with distinct compositions. After delivery to one surface, proteins can be…”
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Phosphoinositide 3-kinase regulates the role of retromer in transcytosis of the polymeric immunoglobulin receptor by Vergés, Marcel, Sebastián, Isabel, Mostov, Keith E.

“…Retromer is a multimeric protein complex that mediates intracellular receptor sorting. One of the roles of retromer is to promote transcytosis of the polymeric…”
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Lamellar lipoproteins uniquely contribute to hyperlipidemia in mice doubly deficient in apolipoprotein E and hepatic lipase by Bergeron, N, Kotite, L, Verges, M, Blanche, P, Hamiton, R.L, Krauss, R.M, Bensadoun, A, Havel, R.J

“…Remnants of triglyceride-rich lipoproteins containing apolipoprotein (apo) B-48 accumulate in apo E-deficient mice, causing pronounced hypercholesterolemia…”
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N -Glycosylation of the voltage-gated sodium channel β2 subunit is required for efficient trafficking of Na V 1.5/β2 to the plasma membrane by Cortada, Eric, Brugada, Ramon, Verges, Marcel

“…The voltage-gated sodium channel is critical for cardiomyocyte function and consists of a protein complex comprising a pore-forming α subunit and two…”
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A Missense Mutation in the Sodium Channel [beta]2 Subunit Reveals SCN2B as a New Candidate Gene for Brugada Syndrome by Riuro, Helena, Beltran-Alvarez, Pedro, Tarradas, Anna, Selga, Elisabet, Campuzano, Oscar, Verges, Marcel, Pagans, Sara, Iglesias, Anna, Brugada, Josep, Brugada, Pedro, Vazquez, Francisco M, Perez, Guillermo J, Scornik, Fabiana S, Brugada, Ramon

“…Brugada Syndrome (BrS) is a familial disease associated with sudden cardiac death. A 20%-25% of BrS patients carry genetic defects that cause loss-of-function…”
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Subcellular localisation of retromer in post-endocytic pathways of polarised Madin-Darby canine kidney cells by Mellado, Maravillas, Cuartero, Yasmina, Brugada, Ramon, Verges, Marcel

“…Background information Retromer is required for endosome‐to‐Golgi retrieval of the cation‐independent mannose 6‐phosphate receptor (CI‐MPR), allowing delivery…”
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