Search Results - "Verena, I"

Genomic Classification and Prognosis in Acute Myeloid Leukemia by Papaemmanuil, Elli, Gerstung, Moritz, Bullinger, Lars, Gaidzik, Verena I, Paschka, Peter, Roberts, Nicola D, Potter, Nicola E, Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Gundem, Gunes, Van Loo, Peter, Martincorena, Inigo, Ganly, Peter, Mudie, Laura, McLaren, Stuart, O’Meara, Sarah, Raine, Keiran, Jones, David R, Teague, Jon W, Butler, Adam P, Greaves, Mel F, Ganser, Arnold, Döhner, Konstanze, Schlenk, Richard F, Döhner, Hartmut, Campbell, Peter J

“…The authors identify 11 discrete genetic subsets of acute myeloid leukemia on the basis of the expression and coexpression of particular mutations. Prospective…”
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Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML by Thol, Felicitas, Gabdoulline, Razif, Liebich, Alessandro, Klement, Piroska, Schiller, Johannes, Kandziora, Christian, Hambach, Lothar, Stadler, Michael, Koenecke, Christian, Flintrop, Madita, Pankratz, Mira, Wichmann, Martin, Neziri, Blerina, Büttner, Konstantin, Heida, Bennet, Klesse, Sabrina, Chaturvedi, Anuhar, Kloos, Arnold, Göhring, Gudrun, Schlegelberger, Brigitte, Gaidzik, Verena I., Bullinger, Lars, Fiedler, Walter, Heim, Albert, Hamwi, Iyas, Eder, Matthias, Krauter, Jürgen, Schlenk, Richard F., Paschka, Peter, Döhner, Konstanze, Döhner, Hartmut, Ganser, Arnold, Heuser, Michael

“…Molecular measurable residual disease (MRD) assessment is not established in approximately 60% of acute myeloid leukemia (AML) patients because of the lack of…”
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Precision oncology for acute myeloid leukemia using a knowledge bank approach by Gerstung, Moritz, Papaemmanuil, Elli, Martincorena, Inigo, Bullinger, Lars, Gaidzik, Verena I, Paschka, Peter, Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Ganly, Peter, Ganser, Arnold, McDermott, Ultan, Döhner, Konstanze, Schlenk, Richard F, Döhner, Hartmut, Campbell, Peter J

“…Peter Campbell, Hartmut Döhner and colleagues present an analysis of genetic mutations and clinical information from 1,540 patients with acute myeloid…”
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Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia by Pan, Rongqing, Hogdal, Leah J, Benito, Juliana M, Bucci, Donna, Han, Lina, Borthakur, Gautam, Cortes, Jorge, DeAngelo, Daniel J, Debose, Lakeisha, Mu, Hong, Döhner, Hartmut, Gaidzik, Verena I, Galinsky, Ilene, Golfman, Leonard S, Haferlach, Torsten, Harutyunyan, Karine G, Hu, Jianhua, Leverson, Joel D, Marcucci, Guido, Müschen, Markus, Newman, Rachel, Park, Eugene, Ruvolo, Peter P, Ruvolo, Vivian, Ryan, Jeremy, Schindela, Sonja, Zweidler-McKay, Patrick, Stone, Richard M, Kantarjian, Hagop, Andreeff, Michael, Konopleva, Marina, Letai, Anthony G

“…B-cell leukemia/lymphoma 2 (BCL-2) prevents commitment to programmed cell death at the mitochondrion. It remains a challenge to identify those tumors that are…”
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IDH1 and IDH2 Mutations Are Frequent Genetic Alterations in Acute Myeloid Leukemia and Confer Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia With NPM1 Mutation Without FLT3 Internal Tandem Duplication by PASCHKA, Peter, SCHLENK, Richard F, HORST, Heinz-A, GERMING, Ulrich, DÖHNER, Hartmut, DÖHNER, Konstanze, GAIDZIK, Verena I, HABDANK, Marianne, KRÖNKE, Jan, BULLINGER, Lars, SPÄTH, Daniela, KAYSER, Sabine, ZUCKNICK, Manuela, GÖTZE, Katharina

“…To analyze the frequency and prognostic impact of isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2) mutations in acute myeloid leukemia…”
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Gemtuzumab Ozogamicin in NPM1 -Mutated Acute Myeloid Leukemia: Early Results From the Prospective Randomized AMLSG 09-09 Phase III Study by Schlenk, Richard F, Paschka, Peter, Krzykalla, Julia, Weber, Daniela, Kapp-Schwoerer, Silke, Gaidzik, Verena I, Leis, Claudia, Fiedler, Walter, Kindler, Thomas, Schroeder, Thomas, Mayer, Karin, Lübbert, Michael, Wattad, Mohammed, Götze, Katharina, Horst, Heinz A, Koller, Elisabeth, Wulf, Gerald, Schleicher, Jan, Bentz, Martin, Greil, Richard, Hertenstein, Bernd, Krauter, Jürgen, Martens, Uwe, Nachbaur, David, Abu Samra, Maisun, Girschikofsky, Michael, Basara, Nadezda, Benner, Axel, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Döhner, Konstanze, Döhner, Hartmut

“…High CD33 expression in acute myeloid leukemia (AML) with mutated provides a rationale for the evaluation of gemtuzumab ozogamicin (GO) in this AML entity. We…”
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Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation by Cocciardi, Sibylle, Dolnik, Anna, Kapp-Schwoerer, Silke, Rücker, Frank G., Lux, Susanne, Blätte, Tamara J., Skambraks, Sabrina, Krönke, Jan, Heidel, Florian H., Schnöder, Tina M., Corbacioglu, Andrea, Gaidzik, Verena I., Paschka, Peter, Teleanu, Veronica, Göhring, Gudrun, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Weber, Daniela, Sträng, Eric, Kestler, Hans A., Döhner, Hartmut, Bullinger, Lars, Döhner, Konstanze

“…Mutations in the nucleophosmin 1 ( NPM1 ) gene are considered founder mutations in the pathogenesis of acute myeloid leukemia (AML). To characterize the…”
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Multivalent probes in molecular imaging: reality or future?: (Trends in Molecular Medicine, 27:4 p:379–393, 2021) by Böhmer, Verena I., Szymanski, Wiktor, Feringa, Ben L., Elsinga, Philip H.

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Main-chain degradable single-chain cyclized polymers as gene delivery vectors by Gao, Yongsheng, Böhmer, Verena I., Zhou, Dezhong, Zhao, Tianyu, Wang, Wenxin, Paulusse, Jos M.J.

“…Single-chain technology (SCT) allows the manipulation of polymeric architectures at an individual polymer chain level, providing a new platform for the…”
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Differential impact of allelic ratio and insertion site in FLT3-ITD–positive AML with respect to allogeneic transplantation by Schlenk, Richard F., Kayser, Sabine, Bullinger, Lars, Kobbe, Guido, Casper, Jochen, Ringhoffer, Mark, Held, Gerhard, Brossart, Peter, Lübbert, Michael, Salih, Helmut R., Kindler, Thomas, Horst, Heinz A., Wulf, Gerald, Nachbaur, David, Götze, Katharina, Lamparter, Alexander, Paschka, Peter, Gaidzik, Verena I., Teleanu, Veronica, Späth, Daniela, Benner, Axel, Krauter, Jürgen, Ganser, Arnold, Döhner, Hartmut, Döhner, Konstanze

“…The objective was to evaluate the prognostic and predictive impact of allelic ratio and insertion site (IS) of internal tandem duplications (ITDs), as well as…”
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Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia by Krönke, Jan, Bullinger, Lars, Teleanu, Veronica, Tschürtz, Florian, Gaidzik, Verena I., Kühn, Michael W.M., Rücker, Frank G., Holzmann, Karlheinz, Paschka, Peter, Kapp-Schwörer, Silke, Späth, Daniela, Kindler, Thomas, Schittenhelm, Marcus, Krauter, Jürgen, Ganser, Arnold, Göhring, Gudrun, Schlegelberger, Brigitte, Schlenk, Richard F., Döhner, Hartmut, Döhner, Konstanze

“…Mutations in the nucleophosmin 1 (NPM1) gene are considered a founder event in the pathogenesis of acute myeloid leukemia (AML). To address the role of clonal…”
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Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD by Schlenk, Richard F., Weber, Daniela, Fiedler, Walter, Salih, Helmut R., Wulf, Gerald, Salwender, Hans, Schroeder, Thomas, Kindler, Thomas, Lübbert, Michael, Wolf, Dominik, Westermann, Jörg, Kraemer, Doris, Götze, Katharina S., Horst, Heinz-August, Krauter, Jürgen, Girschikofsky, Michael, Ringhoffer, Mark, Südhoff, Thomas, Held, Gerhard, Derigs, Hans-Günter, Schroers, Roland, Greil, Richard, Grießhammer, Martin, Lange, Elisabeth, Burchardt, Alexander, Martens, Uwe, Hertenstein, Bernd, Marretta, Lore, Heuser, Michael, Thol, Felicitas, Gaidzik, Verena I., Herr, Wolfgang, Krzykalla, Julia, Benner, Axel, Döhner, Konstanze, Ganser, Arnold, Paschka, Peter, Döhner, Hartmut

“…Patients with acute myeloid leukemia (AML) and a FLT3 internal tandem duplication (ITD) have poor outcomes to current treatment. A phase 2…”
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Adding dasatinib to intensive treatment in core-binding factor acute myeloid leukemia—results of the AMLSG 11-08 trial by Paschka, Peter, Schlenk, Richard F, Weber, Daniela, Benner, Axel, Bullinger, Lars, Heuser, Michael, Gaidzik, Verena I, Thol, Felicitas, Agrawal, Mridul, Teleanu, Veronica, Lübbert, Michael, Fiedler, Walter, Radsak, Markus, Krauter, Jürgen, Horst, Heinz-A., Greil, Richard, Mayer, Karin, Kündgen, Andrea, Martens, Uwe, Heil, Gerhard, Salih, Helmut R, Hertenstein, Bernd, Schwänen, Carsten, Wulf, Gerald, Lange, Elisabeth, Pfreundschuh, Michael, Ringhoffer, Mark, Girschikofsky, Michael, Heinicke, Thomas, Kraemer, Doris, Göhring, Gudrun, Ganser, Arnold, Döhner, Konstanze, Döhner, Hartmut

“…In this phase Ib/IIa study (ClinicalTrials.gov Identifier: NCT00850382) of the German-Austrian AML Study Group (AMLSG) the multikinase inhibitor dasatinib was…”
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Malaria burden and artemisinin resistance in the mobile and migrant population on the Thai-Myanmar border, 1999-2011: an observational study by Carrara, Verena I, Lwin, Khin Maung, Phyo, Aung Pyae, Ashley, Elizabeth, Wiladphaingern, Jacher, Sriprawat, Kanlaya, Rijken, Marcus, Boel, Machteld, McGready, Rose, Proux, Stephane, Chu, Cindy, Singhasivanon, Pratap, White, Nicholas, Nosten, François

“…The Shoklo Malaria Research Unit has been working on the Thai-Myanmar border for 25 y providing early diagnosis and treatment (EDT) of malaria. Transmission of…”
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Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai—Myanmar Border (2003–2013): The Role of Parasite Genetic Factors by Phyo, Aung Pyae, Ashley, Elizabeth A., Anderson, Tim J. C., Bozdech, Zbynek, Carrara, Verena I., Sriprawat, Kanlaya, Nair, Shalini, White, Marina McDew, Dziekan, Jerzy, Ling, Clare, Proux, Stephane, Konghahong, Kamonchanok, Jeeyapant, Atthanee, Woodrow, Charles J., Imwong, Mallika, McGready, Rose, Lwin, Khin Maung, Day, Nicholas P. J., White, Nicholas J., Nosten, Francois

“…Background. Deployment of mefloquine-artesunate (MAS3) on the Thailand-Myanmar border has led to a sustained reduction in falciparum malaria, although…”
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"I can't read and don't understand": Health literacy and health messaging about folic acid for neural tube defect prevention in a migrant population on the Myanmar-Thailand border by Gilder, Mary Ellen, Moo, Pru, Hashmi, Ahmar, Praisaengdet, Norda, Wai, Kerry, Pimanpanarak, Mupawjay, Carrara, Verena I, Angkurawaranon, Chaisiri, Jiraporncharoen, Wichuda, McGready, Rose

“…Health literacy is increasingly recognized as an important determinant of health outcomes, but definition, measurement tools, and interventions are lacking…”
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Monitoring of Minimal Residual Disease in NPM1-Mutated Acute Myeloid Leukemia: A Study From the German-Austrian Acute Myeloid Leukemia Study Group by KRÖNKE, Jan, SCHLENK, Richard F, SPÄTH, Daniela, LÜBBERT, Michael, WATTAD, Mohammed, KINDLER, Thomas, SALIH, Helmut R, HELD, Gerhard, NACHBAUR, David, VON LILIENFELD-TOAL, Marie, GERMING, Ulrich, HAASE, Detlef, JENSEN, Kai-Ole, MERGENTHALER, Hans-Günther, KRAUTER, Jürgen, GANSER, Arnold, GÖHRING, Gudrun, SCHLEGELBERGER, Brigitte, DÖHNER, Hartmut, DÖHNER, Konstanze, TSCHÜRTZ, Florian, CORBACIOGLU, Andrea, GAIDZIK, Verena I, PASCHKA, Peter, ONKEN, Shiva, EIWEN, Karina, HABDANK, Marianne

“…To evaluate the prognostic value of minimal residual disease (MRD) in patients with acute myeloid leukemia (AML) with NPM1 mutation (NPM1(mut)). RNA-based…”
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Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia by Hirsch, Susanne, Blätte, Tamara J, Grasedieck, Sarah, Cocciardi, Sibylle, Rouhi, Arefeh, Jongen-Lavrencic, Mojca, Paschka, Peter, Krönke, Jan, Gaidzik, Verena I, Döhner, Hartmut, Schlenk, Richard F, Kuchenbauer, Florian, Döhner, Konstanze, Dolnik, Anna, Bullinger, Lars

“…In acute myeloid leukemia, there is growing evidence for splicing pattern deregulation, including differential expression of linear splice isoforms of the…”
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TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome by Rücker, Frank G., Schlenk, Richard F., Bullinger, Lars, Kayser, Sabine, Teleanu, Veronica, Kett, Helena, Habdank, Marianne, Kugler, Carla-Maria, Holzmann, Karlheinz, Gaidzik, Verena I., Paschka, Peter, Held, Gerhard, von Lilienfeld-Toal, Marie, Lübbert, Michael, Fröhling, Stefan, Zenz, Thorsten, Krauter, Jürgen, Schlegelberger, Brigitte, Ganser, Arnold, Lichter, Peter, Döhner, Konstanze, Döhner, Hartmut

“…To assess the frequency of TP53 alterations and their correlation with other genetic changes and outcome in acute myeloid leukemia with complex karyotype…”
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Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin by Schmalbrock, Laura K., Dolnik, Anna, Cocciardi, Sibylle, Sträng, Eric, Theis, Frauke, Jahn, Nikolaus, Panina, Ekaterina, Blätte, Tamara J., Herzig, Julia, Skambraks, Sabrina, Rücker, Frank G., Gaidzik, Verena I., Paschka, Peter, Fiedler, Walter, Salih, Helmut R., Wulf, Gerald, Schroeder, Thomas, Lübbert, Michael, Schlenk, Richard F., Thol, Felicitas, Heuser, Michael, Larson, Richard A., Ganser, Arnold, Stunnenberg, Hendrik G., Minucci, Saverio, Stone, Richard M., Bloomfield, Clara D., Döhner, Hartmut, Döhner, Konstanze, Bullinger, Lars

“…In the international randomized phase 3 RATIFY (Randomized AML Trial In FLT3 in patients less than 60 Years old) trial, the multikinase inhibitor midostaurin…”
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