Search Results - "Veremeeva, Polina N."
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New Allosteric Modulators of AMPA Receptors: Synthesis and Study of Their Functional Activity by Radioligand-Receptor Binding Analysis
Published in International journal of molecular sciences (18-06-2023)“…The synthetic approaches to three new AMPA receptor modulators-derivatives of 1,11-dimethyl-3,6,9-triazatricyclo[7.3.1.1 ]tetradecane-4,8,12-trione-had been…”
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Stimulus-sensitive liposomal delivery system based on new 3,7-diazabicyclo[3.3.1]nonane derivatives
Published in Bioorganic & medicinal chemistry letters (01-05-2021)“…[Display omitted] 3,7-Diazabicyclo[3.3.1]nonane scaffold can serve as a basis for the design of molecular switches stimulating the fast release of water…”
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Bispidinone-based molecular switches for construction of stimulus-sensitive liposomal containers
Published in Tetrahedron (18-02-2014)“…It is demonstrated that new lipid-like amphiphilic compounds, derivatives of 3,7-diazabicyclo[3.3.1]nonan-9-one (bispidinone) with long alkyl substituents, can…”
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pH-Sensitive liposomes with embedded 3,7-diazabicyclo[3.3.1]nonane derivative
Published in Mendeleev communications (01-05-2014)“…1,5-Dinitro-3,7-ditridecyl-3,7-diazabicyclo[3.3.1]nonane modulates the permeability of liposomal membranes as pH of surrounding aqueous solution decreases from…”
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Synthesis of 3,7-diacyl-1,5-dimethyl-3,7-diazabicyclo[3.3.1]nonane derivatives as promising lipid bilayer modifiers
Published in Tetrahedron (16-08-2019)“…Novel 3,7-bis(dialkylaminoacetyl)-1,5-dimethyl-3,7-diazabicyclo[3.3.1]nonanes were synthesized, which can undergo conformational reorganization under the…”
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7-Benzyl-1,5-dimethyl-3-piperonyloyl-3,7-diazabicyclo[3.3.1]nonan-9-one as an allosteric modulator of glutamatergic system
Published in Mendeleev communications (01-05-2024)“…[Display omitted] The title compound has been synthesized and assessed in vitro by means of electrophysiological patch clamp technique revealing a positive…”
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Positive and negative AMPA receptor modulators based on tricyclic bispidine derivative: Minor structural change inverts the type of activity
Published in Mendeleev communications (01-05-2022)“…[Display omitted] Two new potent AMPA receptor allosteric modulators,…”
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Tricyclic derivatives of bispidine as AMPA receptor allosteric modulators
Published in Mendeleev communications (01-11-2019)“…[Display omitted] Four new tricyclic derivatives of 3,7-diazabicyclo[3.3.1]-nonane (bispidine) have been synthesized. In vitro patch clamp investigation has…”
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New 1,11-dimethyl-3,6,9-triazatricyclo[7.3.1.13,11]tetradecane-4,8,12-trione derivative as an allosteric modulator of the glutamatergic system
Published in Mendeleev communications (01-01-2023)“…[Display omitted] An optimized synthesis of…”
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Synthesis of amphiphilic diacyl derivatives of 3,7-diazabicyclo[3.3.1]nonan-9-one
Published in Mendeleev communications (01-01-2018)“…[Display omitted] Novel amphiphilic candidates for incorporation into lipid bilayer, 3,7-diacyl-3,7-diazabicyclo[3.3.1]nonan-9-ones, have been synthesized…”
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