Search Results - "Vereecke, H E M"

Frontal electroencephalogram based drug, sex, and age independent sedation level prediction using non-linear machine learning algorithms by Ramaswamy, S. M., Kuizenga, M. H., Weerink, M. A. S., Vereecke, H. E. M., Struys, M. M. R. F., Belur Nagaraj, S.

“…Brain monitors which track quantitative electroencephalogram (EEG) signatures to monitor sedation levels are drug and patient specific. There is a need for…”
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Optimizing intravenous drug administration by applying pharmacokinetic/pharmacodynamic concepts by Struys, M.M.R.F., Sahinovic, M., Lichtenbelt, B.J., Vereecke, H.E.M., Absalom, A.R.

“…This review discusses the ways in which anaesthetists can optimize anaesthetic–analgesic drug administration by utilizing pharmacokinetic and pharmacodynamic…”
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Comparison of haemodynamic- and electroencephalographic-monitored effects evoked by four combinations of effect-site concentrations of propofol and remifentanil, yielding a predicted tolerance to laryngoscopy of 90 by van den Berg, J. P., Absalom, A. R., Venema, A. M., Kalmar, A. F., Van Amsterdam, K., Hannivoort, L. N., Proost, J. H., Meier, S., Scheeren, T. W. L., Struys, M. M. R. F., Vereecke, H. E. M.

“…This prospective study evaluates haemodynamic and electroencephalographic effects observed when administering four combinations of effect-site concentrations…”
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Study of the time course of the clinical effect of propofol compared with the time course of the predicted effect-site concentration: performance of three pharmacokinetic–dynamic models by Coppens, M., Van Limmen, J.G.M., Schnider, T., Wyler, B., Bonte, S., Dewaele, F., Struys, M.M.R.F., Vereecke, H.E.M.

“…In the ideal pharmacokinetic–dynamic (PK–PD) model for calculating the predicted effect-site concentration of propofol (CePROP), for any CePROP, the…”
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Dexmedetomidine pharmacokinetic–pharmacodynamic modelling in healthy volunteers: 1. Influence of arousal on bispectral index and sedation by Colin, P.J., Hannivoort, L.N., Eleveld, D.J., Reyntjens, K.M.E.M., Absalom, A.R., Vereecke, H.E.M., Struys, M.M.R.F.

“…Dexmedetomidine, a selective α2-adrenoreceptor agonist, has unique characteristics, such as maintained respiratory drive and production of arousable sedation…”
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Dexmedetomidine pharmacodynamics in healthy volunteers: 2. Haemodynamic profile by Colin, P.J., Hannivoort, L.N., Eleveld, D.J., Reyntjens, K.M.E.M., Absalom, A.R., Vereecke, H.E.M., Struys, M.M.R.F.

“…Dexmedetomidine, a selective α2-adrenoreceptor agonist, has unique characteristics, with little respiratory depression and rousability during sedations. We…”
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A comparison of bispectral index and ARX‐derived auditory evoked potential index in measuring the clinical interaction between ketamine and propofol anaesthesia by Vereecke, H. E. M., Struys, M. M. R. F., Mortier, E. P.

“…Summary We evaluated the effects of a bolus (0.4 mg.kg−1) and continuous infusion (1 mg.kg−1.h−1) of ketamine on Bispectral Index (BIS) and A‐Line® ARX Index…”
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Pharmacokinetic and pharmacodynamic interactions in anaesthesia. A review of current knowledge and how it can be used to optimize anaesthetic drug administration by van den Berg, J.P., Vereecke, H.E.M., Proost, J.H., Eleveld, D.J., Wietasch, J.K.G., Absalom, A.R., Struys, M.M.R.F.

“…This review describes the basics of pharmacokinetic and pharmacodynamic drug interactions and methodological points of particular interest when designing drug…”
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Test of neural inertia in humans during general anaesthesia by Kuizenga, M H, Colin, P J, Reyntjens, K M E M, Touw, D J, Nalbat, H, Knotnerus, F H, Vereecke, H E M, Struys, M M R F

“…Neural inertia is defined as the tendency of the central nervous system to resist transitions between arousal states. This phenomenon has been observed in mice…”
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Probability to tolerate laryngoscopy and noxious stimulation response index as general indicators of the anaesthetic potency of sevoflurane, propofol, and remifentanil by Hannivoort, L.N., Vereecke, H.E.M., Proost, J.H., Heyse, B.E.K., Eleveld, D.J., Bouillon, T.W., Struys, M.M.R.F., Luginbühl, M

“…The probability to tolerate laryngoscopy (PTOL) and its derivative, the noxious stimulation response index (NSRI), have been proposed as measures of potency of…”
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Comparing the haemodynamic effects of high- and low-dose opioid anaesthesia: a secondary analysis of a randomised controlled trial by Marges, O M, Nieboer, J P, de Keijzer, I N, Rettab, R, van Amsterdam, K, Scheeren, T W L, Absalom, A R A, Vereecke, H E M, Struys, M M R F, Vos, J J, van den Berg, J P

“…Post-induction hypotension (MAP < 65 mmHg) occurs frequently and is usually caused by the cardiovascular adverse effects of the anaesthetic induction drugs…”
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Auto-mutual information function of the EEG as a measure of depth of anesthesia by Julitta, B., Vallverdu, M., Melia, U. S. P., Tupaika, N., Jospin, M., Jensen, E. W., Struys, M. M. R. F., Vereecke, H. E. M., Caminal, P.

“…Monitoring the depth of anesthesia (DOA) is necessary in order to decrease the incident of awareness in anesthesia and to prevent delays in the recovery phase…”
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