Search Results - "Verdun di Cantogno, Ludovica"
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1
Approaching heterogeneity of human epidermal growth factor receptor 2 in surgical specimens of gastric cancer
Published in Human pathology (01-11-2012)“…Summary Gastric cancer shows intratumoral heterogeneity for human epidermal growth factor receptor 2 expression. We evaluated whether the number of tissue…”
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2
FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations
Published in International journal of molecular sciences (10-01-2023)“…amplification represents the leading oncogenic pathway and diagnostic hallmark of liposarcoma, whose assessment is based on Fluorescence In Situ Hybridization…”
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3
Immunohistochemical and molecular profiling of histologically defined apocrine carcinomas of the breast
Published in Human pathology (01-09-2015)“…Summary Despite the marked improvement in the understanding of molecular mechanisms and classification of apocrine carcinoma, little is known about its…”
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4
A “Weighted” Fluorescence In Situ Hybridization Strengthens the Favorable Prognostic Value of 1p/19q Codeletion in Pure and Mixed Oligodendroglial Tumors
Published in Journal of neuropathology and experimental neurology (01-05-2013)“…ABSTRACTEvaluation of the molecular status of 1p and 19q is a major relevant diagnostic, prognostic, and predictive tool for oligodendroglial brain tumors…”
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5
The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries
Published in Nature communications (16-03-2017)“…The docking protein p140Cap negatively regulates tumour cell features. Its relevance on breast cancer patient survival, as well as its ability to counteract…”
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6
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis
Published in The Journal of pathology (01-09-2009)“…Approximately 8% of breast cancers show increased copy numbers of chromosome 17 centromere (CEP17) by fluorescence in situ hybridization (FISH) (ie average…”
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7
A collection of primary tissue cultures of tumors from vacuum packed and cooled surgical specimens: a feasibility study
Published in PloS one (30-09-2013)“…Primary cultures represent an invaluable tool to set up functional experimental conditions; however, creation of tissue cultures from solid tumors is…”
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8
Differences and homologies of chromosomal alterations within and between breast cancer cell lines: a clustering analysis
Published in Molecular cytogenetics (23-01-2014)“…The MCF7 (ER+/HER2-), T47D (ER+/HER2-), BT474 (ER+/HER2+) and SKBR3 (ER-/HER2+) breast cancer cell lines are widely used in breast cancer research as paradigms…”
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9
SS18-SSX Antibody: A Useful Tool to Save Time and Reduce Costs in Synovial Sarcoma Diagnosis. Proposal of a Novel Diagnostic Algorithm
Published in The journal of histochemistry and cytochemistry (01-07-2023)“…Synovial sarcoma is a rare malignant mesenchymal neoplasm mostly affecting young adults, characterized by a specific translocation which results in the fusion…”
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10
Evolutionary and clinical neocentromeres: two faces of the same coin
Published in Chromosoma (01-08-2008)“…It has been hypothesized that human clinical neocentromeres and evolutionary novel centromeres (ENC) represent two faces of the same phenomenon. However, there…”
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Gene Status in HER2 Equivocal Breast Carcinomas: Impact of Distinct Recommendations and Contribution of a Polymerase Chain Reaction‐Based Method
Published in The oncologist (Dayton, Ohio) (01-11-2014)“…Background. The primary objectives of this study on carcinomas with equivocal HER2 expression were to assess the impact of distinct recommendations with regard…”
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12
The Dilemma of HER2 Double-equivocal Breast Carcinomas: Genomic Profiling and Implications for Treatment
Published in The American journal of surgical pathology (01-09-2018)“…The American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) 2013 guidelines for HER2 assessment have increased the number of HER2…”
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13
CAVEOLIN-1 expression in brain metastasis from lung cancer predicts worse outcome and radioresistance, irrespective of tumor histotype
Published in Oncotarget (06-10-2015)“…Brain metastases develop in one-third of patients with non-small-cell lung cancer and are associated with a dismal prognosis, irrespective of surgery or…”
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14
MET mutations are associated with aggressive and radioresistant brain metastatic non-small-cell lung cancer
Published in Neuro-oncology (Charlottesville, Va.) (01-04-2016)Get full text
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15
Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases
Published in Journal of translational medicine (01-05-2017)“…Immunohistochemistry (IHC) and fluorescent-in situ hybridization (FISH) are standard methods to assess human epidermal growth factor receptor 2 (HER2) status…”
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16
Effect of low doses of estradiol and tamoxifen on breast cancer cell karyotypes
Published in Endocrine-related cancer (01-08-2016)“…Evidence supports a role of 17&-estradiol (E2) in carcinogenesis and the large majority of breast carcinomas are dependent on estrogen. The anti-estrogen…”
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Unraveling the chromosome 17 patterns of FISH in interphase nuclei: an in-depth analysis of the HER2 amplicon and chromosome 17 centromere by karyotyping, FISH and M-FISH in breast cancer cells
Published in BMC cancer (07-12-2014)“…In diagnostic pathology, HER2 status is determined in interphase nuclei by fluorescence in situ hybridization (FISH) with probes for the HER2 gene and for the…”
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18
A de novo X;8 translocation creates a PTK2-THOC2 gene fusion with THOC2 expression knockdown in a patient with psychomotor retardation and congenital cerebellar hypoplasia
Published in Journal of medical genetics (01-08-2013)“…We identified a balanced de novo translocation involving chromosomes Xq25 and 8q24 in an eight year-old girl with a non-progressive form of congenital ataxia,…”
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Correction: Author Correction: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries
Published in Nature communications (30-03-2018)“…Nature Communications 8: Article number: 14797 (2017); Published online 16 March 2017; Updated 30 March 2018 In the original version of this Article, the…”
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20
Presenting phenotype and clinical evaluation in a cohort of 22 Williams–Beuren syndrome patients
Published in European journal of medical genetics (01-09-2007)“…Abstract Williams–Beuren syndrome (WS) is a rare multi-system genomic disorder, caused by 7q11.23 microdeletion with a prevalence of 1/7500–1/20,000 live…”
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