Search Results - "Verdone, James"

Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters by Cheung, Kevin J., Padmanaban, Veena, Silvestri, Vanesa, Schipper, Koen, Cohen, Joshua D., Fairchild, Amanda N., Gorin, Michael A., Verdone, James E., Pienta, Kenneth J., Bader, Joel S., Ewald, Andrew J.

“…Recent genomic studies challenge the conventional model that each metastasis must arise from a single tumor cell and instead reveal that metastases can be…”
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Tobacco treatment in the setting of lung cancer screening by Verdone, James E, Marciniak, Ellen T, Deepak, Janaki

“…Lung cancer screening by low-dose CT is an increasingly implemented preventive medicine tool. Screening for lung cancer is incomplete without addressing…”
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Disseminated tumor cells and dormancy in prostate cancer metastasis by van der Toom, Emma E, Verdone, James E, Pienta, Kenneth J

“…Graphical abstract…”
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A phased strategy to differentiate human CD14+monocytes into classically and alternatively activated macrophages and dendritic cells by Zarif, Jelani C, Hernandez, James R, Verdone, James E, Campbell, Scott P, Drake, Charles G, Pienta, Kenneth J

“…There are currently several in vitro strategies to differentiate human CD14(+) monocytes isolated from peripheral blood mononuclear cells (PBMCs) into the M1…”
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Technical challenges in the isolation and analysis of circulating tumor cells by van der Toom, Emma E, Verdone, James E, Gorin, Michael A, Pienta, Kenneth J

“…Increasing evidence suggests that cancer cells display dynamic molecular changes in response to systemic therapy. Circulating tumor cells (CTCs) in the…”
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Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells by Shiraishi, Takumi, Verdone, James E, Huang, Jessie, Kahlert, Ulf D, Hernandez, James R, Torga, Gonzalo, Zarif, Jelani C, Epstein, Tamir, Gatenby, Robert, McCartney, Annemarie, Elisseeff, Jennifer H, Mooney, Steven M, An, Steven S, Pienta, Kenneth J

“…The ability of a cancer cell to detach from the primary tumor and move to distant sites is fundamental to a lethal cancer phenotype. Metabolic transformations…”
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Circulating tumour cells as biomarkers of prostate, bladder, and kidney cancer by Gorin, Michael A., Verdone, James E., van der Toom, Emma, Bivalacqua, Trinity J., Allaf, Mohamad E., Pienta, Kenneth J.

“…Key Points Circulating tumour cells (CTCs) have been validated as prognostic biomarkers of prostate cancer. These data have been generated with a number of…”
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A Comparative Analysis of Online Versus in-Person Opioid Overdose Awareness and Reversal Training for First-Year Medical Students by Goss, Nathaniel C., Haslund-Gourley, Benjamin, Meredith, Dakota M., Friedman, Andrew V., Kumar, Vishnu K., Samson, Kyle R., Fitzgerald, Ethan J., Damaraju, Shraddha, Verdone, James E., Edelman, Jacob, Anlage, Troy J., Albrecht, Daniel G., Gorisek, Savannah R., Carnevale, Ann, Gadegbeku, Annette B.

“…Physicians trained in opioid use disorder (OUD) harm reduction can mitigate opioid overdose deaths by prescribing naloxone and educating patients about its…”
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Characterization of Urothelial Cancer Circulating Tumor Cells with a Novel Selection-Free Method by Chalfin, Heather J., Kates, Max, van der Toom, Emma E., Glavaris, Stephanie, Verdone, James E., Hahn, Noah M., Pienta, Kenneth J., Bivalacqua, Trinity J., Gorin, Michael A.

“…To investigate circulating tumor cells (CTCs) as biomarkers of urothelial carcinoma (UC). To date, the majority of work on this topic has utilized the…”
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3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification by Kalinin, Alexandr A., Allyn-Feuer, Ari, Ade, Alex, Fon, Gordon-Victor, Meixner, Walter, Dilworth, David, Husain, Syed S., de Wet, Jeffrey R., Higgins, Gerald A., Zheng, Gen, Creekmore, Amy, Wiley, John W., Verdone, James E., Veltri, Robert W., Pienta, Kenneth J., Coffey, Donald S., Athey, Brian D., Dinov, Ivo D.

“…Quantitative analysis of morphological changes in a cell nucleus is important for the understanding of nuclear architecture and its relationship with…”
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Epithelial-mesenchymal transition in prostate cancer is associated with quantifiable changes in nuclear structure by Verdone, James E., Parsana, Princy, Veltri, Robert W., Pienta, Kenneth J.

“…BACKGROUND Prostate cancer progression is concomitant with quantifiable nuclear structure and texture changes as compared to non‐cancer tissue. Malignant…”
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The prostate metastasis suppressor gene NDRG1 differentially regulates cell motility and invasion by Sharma, Anup, Mendonca, Janet, Ying, James, Kim, Hea‐Soo, Verdone, James E., Zarif, Jelani C., Carducci, Michael, Hammers, Hans, Pienta, Kenneth J., Kachhap, Sushant

“…Experimental and clinical evidence suggests that N‐myc downregulated gene 1 (NDRG1) functions as a suppressor of prostate cancer metastasis. Elucidating…”
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Aerobic glycolysis, motility, and cytoskeletal remodeling by Verdone, James E, Zarif, Jelani C, Pienta, Kenneth J

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The Presence of Androgen Receptor Elements Regulates ZEB1 Expression in the Absence of Androgen Receptor by Mooney, Steven M., Parsana, Princy, Hernandez, James R., Liu, Xin, Verdone, James E., Torga, Gonzalo, Harberg, Calvin A., Pienta, Kenneth J.

“…Zinc finger E‐box binding homeobox 1 (ZEB1) is a transcription factor that plays a central role in the epithelial to mesenchymal transition (EMT) of cancer…”
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Abstract 4109: Unbiased detection of disseminated tumor cells in murine bone marrow by Valkenburg, Kenneth C., Hernandez, James R., Amend, Sarah R., Verdone, James E., Gorin, Michael A., Pienta, Kenneth J.

“…Abstract Approximately 20-30% of prostate cancer patients develop disease recurrence and metastasis years after initial therapy. This is thought to be largely…”
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Alternative CD44 splicing identifies epithelial prostate cancer cells from the mesenchymal counterparts by Hernandez, James R., Kim, John J., Verdone, James E., Liu, Xin, Torga, Gonzalo, Pienta, Kenneth J., Mooney, Steven M.

“…An epithelial to mesenchymal transition (EMT) has been shown to be a necessary precursor to prostate cancer metastasis. Additionally, the differential…”
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Nucleolin staining may aid in the identification of circulating prostate cancer cells by Chalfin, Heather J, Verdone, James E, van der Toom, Emma E, Glavaris, Stephanie, Gorin, Michael A, Pienta, Kenneth J

“…Abstract Introduction Circulating tumor cells (CTCs) have great potential as circulating biomarkers for solid malignancies. Currently available assays for CTC…”
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Publisher Correction: 3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification by Kalinin, Alexandr A., Allyn-Feuer, Ari, Ade, Alex, Fon, Gordon-Victor, Meixner, Walter, Dilworth, David, Husain, Syed S., de Wet, Jeffrey R., Higgins, Gerald A., Zheng, Gen, Creekmore, Amy, Wiley, John W., Verdone, James E., Veltri, Robert W., Pienta, Kenneth J., Coffey, Donald S., Athey, Brian D., Dinov, Ivo D.

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
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A simple selection-free method for detecting disseminated tumor cells (DTCs) in murine bone marrow by Valkenburg, Kenneth C, Amend, Sarah R, Verdone, James E, van der Toom, Emma E, Hernandez, James R, Gorin, Michael A, Pienta, Kenneth J

“…Bone metastasis is a lethal and incurable disease. It is the result of the dissemination of cancer cells to the bone marrow. Due to the difficulty in sampling…”
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A surface tension magnetophoretic device for rare cell isolation and characterization by van der Toom, Emma E., Verdone, James E., Jun, Changhan, Petrisor, Doru, Lim, Sunghwan, de la Rosette, Jean J. M. C. H., de Reijke, Theo M., Gorin, Michael A., Pienta, Kenneth J., Stoianovici, Dan

“…The cancer community continues to search for an efficient and cost-effective technique to isolate and characterize circulating cells (CTCs) as a ‘real-time…”
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