Search Results - "Verchinski, Beth A"
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common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function
Published in Proceedings of the National Academy of Sciences - PNAS (03-08-2010)“…The evolutionarily highly conserved neuropeptide oxytocin is a key mediator of social and emotional behavior in mammals, including humans. A common variant…”
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Hierarchical Organization of Human Cortical Networks in Health and Schizophrenia
Published in The Journal of neuroscience (10-09-2008)“…The complex organization of connectivity in the human brain is incompletely understood. Recently, topological measures based on graph theory have provided a…”
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Normal age-related brain morphometric changes: nonuniformity across cortical thickness, surface area and gray matter volume?
Published in Neurobiology of aging (01-03-2012)“…Abstract Normal aging is accompanied by global as well as regional structural changes. While these age-related changes in gray matter volume have been…”
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5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression
Published in Nature neuroscience (01-06-2005)“…Carriers of the short allele of a functional 5' promoter polymorphism of the serotonin transporter gene have increased anxiety-related temperamental traits,…”
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Investigation of Anatomical Thalamo-Cortical Connectivity and fMRI Activation in Schizophrenia
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-2012)“…The purpose of this study was to examine measures of anatomical connectivity between the thalamus and lateral prefrontal cortex (LPFC) in schizophrenia and to…”
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The Brain-Derived Neurotrophic Factor val66met Polymorphism and Variation in Human Cortical Morphology
Published in The Journal of neuroscience (10-11-2004)“…A variation in the BDNF gene (val66met) affects the function of BDNF in neurons, predicts variation in human memory, and is associated with several…”
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Complexity of Prefrontal Cortical Dysfunction in Schizophrenia: More Than Up or Down
Published in The American journal of psychiatry (01-12-2003)“…OBJECTIVE: Numerous neuroimaging studies have examined the function of the dorsolateral prefrontal cortex in schizophrenia; although abnormalities usually are…”
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Impact of interacting functional variants in COMT on regional gray matter volume in human brain
Published in NeuroImage (Orlando, Fla.) (01-03-2009)“…Functional variants in the catechol- O-methyltransferase ( COMT) gene have been shown to impact cognitive function, cortical physiology and risk for…”
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Variation in DISC1 Affects Hippocampal Structure and Function and Increases Risk for Schizophrenia
Published in Proceedings of the National Academy of Sciences - PNAS (14-06-2005)“…Disrupted-in-schizophrenia 1 (DISC1) is a promising schizophrenia candidate gene expressed predominantly within the hippocampus. We typed 12 single-nucleotide…”
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Neurogenetic Effects of OXTR rs2254298 in the Extended Limbic System of Healthy Caucasian Adults
Published in Biological psychiatry (1969) (01-11-2011)Get full text
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Heritability of Brain Morphology Related to Schizophrenia: A Large-Scale Automated Magnetic Resonance Imaging Segmentation Study
Published in Biological psychiatry (1969) (01-03-2008)“…Background Schizophrenia is a devastating psychiatric disorder with a strong genetic component that has been related to a number of structural brain…”
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Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition
Published in The Journal of clinical investigation (01-03-2007)“…Dopamine- and cAMP-regulated phosphoprotein of molecular weight 32 kDa (DARPP-32), encoded by PPP1R1B, is a pivotal integrator of information in…”
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Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function
Published in PLoS genetics (01-11-2008)“…PRODH, encoding proline oxidase (POX), has been associated with schizophrenia through linkage, association, and the 22q11 deletion syndrome (Velo-Cardio-Facial…”
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Automated Quality Assessment of Structural Magnetic Resonance Brain Images Based on a Supervised Machine Learning Algorithm
Published in Frontiers in neuroinformatics (19-12-2016)“…High-resolution three-dimensional magnetic resonance imaging (3D-MRI) is being increasingly used to delineate morphological changes underlying neuropsychiatric…”
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Widespread Reductions of Cortical Thickness in Schizophrenia and Spectrum Disorders and Evidence of Heritability
Published in Archives of general psychiatry (01-05-2009)“…CONTEXT Schizophrenia is a brain disorder with predominantly genetic risk factors, and previous research has identified heritable cortical and subcortical…”
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Allelic Variation in RGS4 Impacts Functional and Structural Connectivity in the Human Brain
Published in The Journal of neuroscience (14-02-2007)“…Regulator of G-protein signaling 4 (RGS4) modulates postsynaptic signal transduction by affecting the kinetics of G alpha-GTP binding. Linkage, association,…”
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Effects of the BDNF Val66Met Polymorphism on White Matter Microstructure in Healthy Adults
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2013)“…The BDNF Val(66)Met polymorphism, a possible risk variant for mental disorders, is a potent modulator of neural plasticity in humans and has been linked to…”
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Handedness, heritability, neurocognition and brain asymmetry in schizophrenia
Published in Brain (London, England : 1878) (01-10-2010)“…Higher rates of non-right-handedness (i.e. left- and mixed-handedness) have been reported in schizophrenia and have been a centrepiece for theories of…”
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Effects of the BDNF Val super(66)Met Polymorphism on White Matter Microstructure in Healthy Adults
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2013)“…The BDNF Val super(66)Met polymorphism, a possible risk variant for mental disorders, is a potent modulator of neural plasticity in humans and has been linked…”
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