Lemierre syndrome

Lemierre syndrome

Lemierre syndrome is a disease that presents with oropharyngeal infection, sepsis, internal jugular vein thrombosis, and septic emboli with the Gram-negative organism Fusobacterium necrophorum cultured as the etiologic agent. Clindamycin, metronidazole and ampicillin-sulbactam are effective antibiot...

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Bibliographic Details
Published in:The Journal of emergency medicine Vol. 28; no. 3; pp. 297 - 299
Main Authors: Nadkarni, Milan D., Verchick, Julie, O’Neill, James C.
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-04-2005
Subjects:
Adolescent
Anti-Bacterial Agents - therapeutic use
Clindamycin - therapeutic use
Female
fusobacterium
Fusobacterium Infections - drug therapy
Fusobacterium Infections - physiopathology
Fusobacterium necrophorum - isolation & purification
Fusobacterium necrophorum - pathogenicity
Humans
Lemierre
oropharyngeal infection
septic emboli
Syndrome
thrombophlebitis
Lemierre
fusobacterium
oropharyngeal infection
septic emboli
thrombophlebitis
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Description
Summary:Lemierre syndrome is a disease that presents with oropharyngeal infection, sepsis, internal jugular vein thrombosis, and septic emboli with the Gram-negative organism Fusobacterium necrophorum cultured as the etiologic agent. Clindamycin, metronidazole and ampicillin-sulbactam are effective antibiotic treatments, although the length of treatment has not been firmly established. The syndrome is seen less frequently in the current age of antibiotics. It is important, however, that physicians be aware of the syndrome as initiation of prompt antibiotic therapy, including anaerobic coverage, is essential for avoiding morbidity and mortality. We describe a case of Lemierre syndrome.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:0736-4679
2352-5029
DOI:10.1016/j.jemermed.2004.09.011