Search Results - "Verbraak, Frank D."

Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus by Sohn, Elliott H., van Dijk, Hille W., Jiao, Chunhua, Kok, Pauline H. B., Jeong, Woojin, Demirkaya, Nazli, Garmager, Allison, Wit, Ferdinand, Kucukevcilioglu, Murat, van Velthoven, Mirjam E. J., DeVries, J. Hans, Mullins, Robert F., Kuehn, Markus H., Schlingemann, Reinier Otto, Sonka, Milan, Verbraak, Frank D., Abràmoff, Michael David

“…Diabetic retinopathy (DR) has long been recognized as a microvasculopathy, but retinal diabetic neuropathy (RDN), characterized by inner retinal…”
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Diagnostic Accuracy of a Device for the Automated Detection of Diabetic Retinopathy in a Primary Care Setting by Verbraak, Frank D, Abramoff, Michael D, Bausch, Gonny C F, Klaver, Caroline, Nijpels, Giel, Schlingemann, Reinier O, van der Heijden, Amber A

“…To determine the diagnostic accuracy in a real-world primary care setting of a deep learning-enhanced device for automated detection of diabetic retinopathy…”
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Retinal thickness in Alzheimer's disease: A systematic review and meta-analysis by den Haan, Jurre, Verbraak, Frank D, Visser, Pieter Jelle, Bouwman, Femke H

“…Abstract Introduction Retinal characteristics are increasingly recognized as biomarkers for neurodegenerative diseases. Retinal thickness measured by optical…”
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Amyloid-beta and phosphorylated tau in post-mortem Alzheimer's disease retinas by den Haan, Jurre, Morrema, Tjado H J, Verbraak, Frank D, de Boer, Johannes F, Scheltens, Philip, Rozemuller, Annemieke J, Bergen, Arthur A B, Bouwman, Femke H, Hoozemans, Jeroen J

“…In-vivo labeling of retinal amyloid-beta(Aβ) and tau has potential as non-invasive biomarker for Alzheimer's disease (AD). However, literature on the presence…”
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Development of retinal structure in perinatally HIV-infected children and adolescents: A longitudinal and cross-sectional assessment by van Genderen, Jason G, Verkade, Charissa R, Van den Hof, Malon, Demirkaya, Nazli, Schrantee, Anouk G M, Verbraak, Frank D, Pajkrt, Dasja

“…In perinatally HIV-infected (PHIV) children, cross-sectional studies reported on subtle structural retinal differences and found associations between the…”
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The spatial relation of diabetic retinal neurodegeneration with diabetic retinopathy by van de Kreeke, Jacoba A, Darma, Stanley, Chan Pin Yin, Jill M P L, Tan, H Stevie, Abramoff, Michael D, Twisk, Jos W R, Verbraak, Frank D

“…Diabetic retinal neurodegeneration (DRN) has been demonstrated in eyes of patients with diabetes mellitus (DM), even in the absence of diabetic retinopathy…”
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Is retinal vasculature a biomarker in amyloid proven Alzheimer's disease? by den Haan, Jurre, van de Kreeke, Jacoba A., van Berckel, Bart N., Barkhof, Frederik, Teunissen, Charlotte E., Scheltens, Philip, Verbraak, Frank D., Bouwman, Femke H.

“…The retina is a potential source of noninvasive vascular biomarkers for Alzheimer's disease (AD). We assessed retinal microvasculature in well-characterized AD…”
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Retinal thickness correlates with parietal cortical atrophy in early-onset Alzheimer's disease and controls by den Haan, Jurre, Janssen, Sarah F., van de Kreeke, Jacoba A., Scheltens, Philip, Verbraak, Frank D., Bouwman, Femke H.

“…The retina may reflect Alzheimer's disease (AD) neuropathological changes and is easily visualized with optical coherence tomography (OCT). Retinal thickness…”
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Retinal thickness as potential biomarker in posterior cortical atrophy and typical Alzheimer's disease by den Haan, Jurre, Csinscik, Lajos, Parker, Tom, Paterson, Ross W, Slattery, Catherine F, Foulkes, Alexander, Bouwman, Femke H, Verbraak, Frank D, Scheltens, Philip, Peto, Tunde, Lengyel, Imre, Schott, Jonathan M, Crutch, Sebastian J, Shakespeare, Timothy J, Yong, Keir X X

“…Retinal thickness can be measured non-invasively with optical coherence tomography (OCT) and may offer compelling potential as a biomarker for Alzheimer's…”
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The quality and usability of smartphone and hand‐held fundus photography, compared to standard fundus photography by Darma, Stanley, Zantvoord, Frank, Verbraak, Frank D.

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Tear biomarkers for Alzheimer's disease screening and diagnosis (the TearAD study): design and rationale of an observational longitudinal multicenter study by van de Sande, Nienke, Ramakers, Inez H G B, Visser, Pieter Jelle, Verhey, Frans R J, Verbraak, Frank D, Bouwman, Femke H, Berendschot, Tos T J M, Nuijts, Rudy M M A, Webers, Carroll A B, Gijs, Marlies

“…Alzheimer's disease (AD) is the most common cause of dementia, and due to increasing life expectancy the number of patients is expected to grow. The diagnosis…”
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In Vivo 3D Determination of Peripapillary Scleral and Retinal Layer Architecture Using Polarization-Sensitive Optical Coherence Tomography by Willemse, Joy, Gräfe, Maximilian G O, Verbraak, Frank D, de Boer, Johannes F

“…The purpose of this paper was to determine the architecture of the collagen fibers of the peripapillary sclera, the retinal nerve fiber layer (RNFL), and…”
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The impact of certolizumab pegol treatment on the incidence of anterior uveitis flares in patients with axial spondyloarthritis: 48-week interim results from C-VIEW by van der Horst-Bruinsma, Irene, van Bentum, Rianne, Verbraak, Frank D, Rath, Thomas, Rosenbaum, James T, Misterska-Skora, Maria, Hoepken, Bengt, Irvin-Sellers, Oscar, VanLunen, Brenda, Bauer, Lars, Rudwaleit, Martin

“…BackgroundAcute anterior uveitis (AAU) is the most common extra-articular manifestation in patients with axial spondyloarthritis (axSpA). C-VIEW investigates…”
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Reduction of anterior uveitis flares in patients with axial spondyloarthritis on certolizumab pegol treatment: final 2-year results from the multicenter phase IV C-VIEW study by van der Horst-Bruinsma, Irene E., van Bentum, Rianne E., Verbraak, Frank D., Deodhar, Atul, Rath, Thomas, Hoepken, Bengt, Irvin-Sellers, Oscar, Thomas, Karen, Bauer, Lars, Rudwaleit, Martin

“…Introduction: Acute anterior uveitis (AAU), affecting up to 40% of patients with axial spondyloarthritis (axSpA), risks permanent visual deficits if not…”
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Ocular biomarkers for cognitive impairment in nonagenarians; a prospective cross-sectional study by van de Kreeke, Jacoba A, Legdeur, Nienke, Badissi, Maryam, Nguyen, H Ton, Konijnenberg, Elles, Tomassen, Jori, Ten Kate, Mara, den Braber, Anouk, Maier, Andrea B, Tan, H Stevie, Verbraak, Frank D, Visser, Pieter Jelle

“…Ocular imaging receives much attention as a source of potential biomarkers for dementia. In the present study, we analyze these ocular biomarkers in…”
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α-Synuclein pathology in post-mortem retina and optic nerve is specific for α-synucleinopathies by Hart de Ruyter, Frederique J., Morrema, Tjado H. J., den Haan, Jurre, Gase, Gina, Twisk, Jos W. R., de Boer, Johannes F., Scheltens, Philip, Bouwman, Femke H., Verbraak, Frank D., Rozemuller, Annemieke J. M., Hoozemans, Jeroen J. M.

“…There is increasing interest in studying retinal biomarkers for various neurodegenerative diseases. Specific protein aggregates associated with…”
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Recent advances in ophthalmic molecular imaging by Ramos de Carvalho, J. Emanuel, MD, Verbraak, Frank D., MD, PhD, Aalders, Maurice C., PhD, van Noorden, Cornelis J., PhD, Schlingemann, Reinier O., MD, PhD

“…Abstract The aim of molecular imaging techniques is the visualization of molecular processes and functional changes in living animals and human patients before…”
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Retinal thickness as a potential biomarker in patients with amyloid-proven early- and late-onset Alzheimer's disease by den Haan, Jurre, van de Kreeke, Jacoba A., Konijnenberg, Elles, ten Kate, Mara, den Braber, Anouk, Barkhof, Frederik, van Berckel, Bart N., Teunissen, Charlotte E., Scheltens, Philip, Visser, Pieter Jelle, Verbraak, Frank D., Bouwman, Femke H.

“…Retinal thickness measured with optical coherence tomography has been proposed as a noninvasive biomarker for Alzheimer's disease (AD). We therefore measured…”
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No difference in retinal fluorescence after oral curcumin intake in amyloid‐proven AD cases compared to controls by den Haan, Jurre, Hart de Ruyter, Frederique J., Lochocki, Benjamin, Kroon, Maurice A.G.M., Kemper, E. Marleen, Teunissen, Charlotte E., Berckel, Bart, Scheltens, Philip, Hoozemans, Jeroen J., Kreeke, Aleid van, Verbraak, Frank D., Boer, Johannes F., Bouwman, Femke H.

“…Introduction Previous work has showed the in vivo presence of retinal amyloid in Alzheimer's disease (AD) patients using curcumin. We aimed to replicate these…”
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Optical coherence tomography to measure the progression of myelopathy in adrenoleukodystrophy by Ballegoij, Wouter J. C., Huffnagel, Irene C., Stadt, Stephanie I. W., Weinstein, Henry C., Bennebroek, Carlien A. M., Engelen, Marc, Verbraak, Frank D.

“…Objective To prospectively determine the value of optical coherence tomography (OCT) as a surrogate outcome measure for the progression of myelopathy in males…”
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