Search Results - "Verbeke, K."

Short chain fatty acids in human gut and metabolic health by Blaak, E E, Canfora, E E, Theis, S, Frost, G, Groen, A K, Mithieux, G, Nauta, A, Scott, K, Stahl, B, van Harsselaar, J, van Tol, R, Vaughan, E E, Verbeke, K

“…Evidence is accumulating that short chain fatty acids (SCFA) play an important role in the maintenance of gut and metabolic health. The SCFA acetate,…”
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Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients by Bammens, B., Evenepoel, P., Keuleers, H., Verbeke, K., Vanrenterghem, Y.

“…Based on in vitro data, protein-bound uremic retention solutes have increasingly been recognized to play a pathophysiological role in the uremic syndrome…”
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In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Hematocrit Predict Tacrolimus Dose Requirements and Clearance in Renal Transplant Patients by de Jonge, H, de Loor, H, Verbeke, K, Vanrenterghem, Y, Kuypers, D R

“…Tacrolimus is metabolized by CYP3A4 and CYP3A5 and is characterized by a narrow therapeutic index and highly variable pharmacokinetics. This cross‐sectional…”
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Clinical trial: a randomized‐controlled crossover study of intrapyloric injection of botulinum toxin in gastroparesis by ARTS, J., HOLVOET, L., CAENEPEEL, P., BISSCHOPS, R., SIFRIM, D., VERBEKE, K., JANSSENS, J., TACK, J.

“…Summary Background  Uncontrolled studies suggest benefit of intrapyloric injection of botulinum toxin (botox) for the treatment of gastroparesis, but…”
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Free p-cresol is associated with cardiovascular disease in hemodialysis patients by Meijers, B.K.I., Bammens, B., De Moor, B., Verbeke, K., Vanrenterghem, Y., Evenepoel, P.

“…Cardiovascular disease (CVD) is highly prevalent in chronic kidney disease, suggesting that molecules retained in uremia might contribute to this increased…”
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Relationship between symptoms and ingestion of a meal in functional dyspepsia by Bisschops, R, Karamanolis, G, Arts, J, Caenepeel, P, Verbeke, K, Janssens, J, Tack, J

“…A subset of functional dyspepsia (FD) patients report meal-related symptoms, possibly representing a pathophysiologically homogeneous subgroup. The aim of the…”
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Influence of ghrelin on gastric emptying and meal‐related symptoms in idiopathic gastroparesis by TACK, J., DEPOORTERE, I., BISSCHOPS, R., VERBEKE, K., JANSSENS, J., PEETERS, T.

“…Summary Background : Ghrelin, the endogenous ligand of the growth hormone secretagogue receptor, is released from the stomach. Animal studies suggest that…”
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CYP3A5 and CYP3A4 but not MDR1 Single‐nucleotide Polymorphisms Determine Long‐term Tacrolimus Disposition and Drug‐related Nephrotoxicity in Renal Recipients by Kuypers, D R J, Jonge, H, Naesens, M, Lerut, E, Verbeke, K, Vanrenterghem, Y

“…The impact of CYP3A and MDR1 gene single‐nucleotide polymorphisms on long‐term tacrolimus disposition and drug‐related toxicity has not been assessed. A study…”
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Influence of erythromycin on gastric emptying and meal related symptoms in functional dyspepsia with delayed gastric emptying by Arts, J, Caenepeel, P, Verbeke, K, Tack, J

“…Background and aims: Although delayed gastric emptying is considered a major pathophysiological mechanism in functional dyspepsia, the efficacy of prokinetic…”
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Superior dialytic clearance of β2-microglobulin and p-cresol by high-flux hemodialysis as compared to peritoneal dialysis by Evenepoel, P., Bammens, B., Verbeke, K., Vanrenterghem, Y.

“…Both residual renal and dialytic clearance confer to the total solute clearance in dialysis patients. Dialytic clearances of the middle molecule…”
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Superior dialytic clearance of beta(2)-microglobulin and p-cresol by high-flux hemodialysis as compared to peritoneal dialysis by Evenepoel, P, Bammens, B, Verbeke, K, Vanrenterghem, Y

“…Both residual renal and dialytic clearance confer to the total solute clearance in dialysis patients. Dialytic clearances of the middle molecule…”
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Baseline microbiota activity and initial bifidobacteria counts influence responses to prebiotic dosing in healthy subjects by DE PRETER, V., VANHOUTTE, T., HUYS, G., SWINGS, J., RUTGEERTS, P., VERBEKE, K.

“…Summary Background  Dietary intervention with prebiotics can cause changes in the colonic microbiota and their metabolic activities. Aim  To investigate…”
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Postprandial symptoms originating from the stomach in functional dyspepsia by Vanheel, H., Vanuytsel, T., Oudenhove, L., Farré, R., Verbeke, K., Tack, J.

“…Background Functional dyspepsia (FD) is characterized by chronic epigastric symptoms. The stomach has been held responsible for the generation of symptoms, but…”
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Acarbose treatment lowers generation and serum concentrations of the protein-bound solute p-cresol: A pilot study by Evenepoel, P., Bammens, B., Verbeke, K., Vanrenterghem, Y.

“…Several protein-bound uremic retention solutes (including p-cresol) originate from colonic bacterial fermentation of protein. Higher colonic availability of…”
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Gastric emptying and different types of reflux in adult patients with cystic fibrosis by Pauwels, A., Blondeau, K., Mertens, V., Farre, R., Verbeke, K., Dupont, L. J., Sifrim, D.

“…Aliment Pharmacol Ther 2011; 34: 799–807 Summary Background  Increased gastro‐oesophageal reflux (GER) is common in patients with cystic fibrosis (CF)…”
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Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro by Kitazawa, T, De Smet, B, Verbeke, K, Depoortere, I, Peeters, T L

“…Background and aims: The gastroprokinetic activities of ghrelin, the natural ligand of the growth hormone secretagogue receptor (GHS-R), prompted us to compare…”
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The effect of arabinoxylooligosaccharides on upper gastroduodenal motility and hunger ratings in humans by Scarpellini, E., Deloose, E., Vos, R., Francois, I., Delcour, J. A., Broekaert, W. F., Verbeke, K., Tack, J.

“…Background and aims Prebiotics such as Arabinoxylooligosaccharides (AXOS) are non‐digestible, fermentable food ingredients stimulating growth/activity of…”
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Will the 13C‐octanoic acid breath test ever replace scintigraphy as the gold standard to assess gastric emptying? by Verbeke, K.

“…The applicability of the 13C‐octanoic acid breath test for the assessment of gastric emptying is discussed. In the current issue of this journal, Keller and…”
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In Vivo CYP3A Activity Is Significantly Lower in Cyclosporine‐Treated as Compared With Tacrolimus‐Treated Renal Allograft Recipients by Jonge, H, Loor, H, Verbeke, K, Vanrenterghem, Y, Kuypers, D R J

“…In vitro studies have identified cyclosporine and tacrolimus as CYP3A inhibitors. In the current study in renal allograft recipients, we used intravenously and…”
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Kinetics of butyrate metabolism in the normal colon and in ulcerative colitis: the effects of substrate concentration and carnitine on the β‐oxidation pathway by De Preter, V., Geboes, K. P., Bulteel, V., Vandermeulen, G., Suenaert, P., Rutgeerts, P., Verbeke, K.

“…Aliment Pharmacol Ther 2011; 34: 526–532 Summary Background  Butyrate, a colonic metabolite of carbohydrates, is considered as the major energy source for the…”
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