Search Results - "Verbeet, Martin"

A Random-sequential Mechanism for Nitrite Binding and Active Site Reduction in Copper-containing Nitrite Reductase by Wijma, Hein J., Jeuken, Lars J.C., Verbeet, Martin P., Armstrong, Fraser A., Canters, Gerard W.

“…The homotrimeric copper-containing nitrite reductase (NiR) contains one type-1 and one type-2 copper center per monomer. Electrons enter through the type-1…”
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Sensing Nitrite through a Pseudoazurin-Nitrite Reductase Electron Transfer Relay by Astier, Yann, Canters, Gerard W., Davis, Jason J., Hill, H. Allen O., Verbeet, Martin P., Wijma, Hein J.

“…Nitrite is converted to nitric oxide by haem or copper‐containing enzymes in denitrifying bacteria during the process of denitrification. In designing an…”
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Role Played by the α-Helix in the Unfolding Pathway and Stability of Azurin: Switching Between Hierarchic and Nonhierarchic Folding by Manetto, Gaetano D, Grasso, Domenico M, Milardi, Danilo, Pappalardo, Matteo, Guzzi, Rita, Sportelli, Luigi, Verbeet, Martin P, Canters, Gerard W, La Rosa, Carmelo

“…The role played by the α-helix in determining the structure, the stability and the unfolding mechanism of azurin was addressed by studying a helix-depleted…”
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The Substrate-Bound Type 2 Copper Site of Nitrite Reductase:  The Nitrogen Hyperfine Coupling of Nitrite Revealed by Pulsed EPR by Fittipaldi, Maria, Wijma, Hein J, Verbeet, Martin P, Canters, Gerard W, Groenen, Edgar J. J, Huber, Martina

“…A pulsed electron paramagnetic resonance study has been performed on the type 2 copper site of nitrite reductase (NiR) from Alcaligenes faecalis. The H145A…”
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Bidirectional Catalysis by Copper-Containing Nitrite Reductase by Wijma, Hein J, Canters, Gerard W, de Vries, Simon, Verbeet, Martin Ph

“…The copper-containing nitrite reductase from Alcaligenes faecalis S-6 was found to catalyze the oxidation of nitric oxide to nitrite, the reverse of its…”
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Effect of the Methionine Ligand on the Reorganization Energy of the Type-1 Copper Site of Nitrite Reductase by Wijma, Hein J, MacPherson, Iain, Farver, Ole, Tocheva, Elitza I, Pecht, Israel, Verbeet, Martin Ph, Murphy, Michael E. P, Canters, Gerard W

“…Copper-containing nitrite reductase harbors a type-1 and a type-2 Cu site. The former acts as the electron acceptor site of the enzyme, and the latter is the…”
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Enzyme therapy for Pompe disease: from science to industrial enterprise by Reuser, Arnold J J, Van Den Hout, Hannerieke, Bijvoet, Agnes G A, Kroos, Marian A, Verbeet, Martin P, Van Der Ploeg, Ans T

“…Pompe disease or glycogen storage disease type II (OMIM 232300) is a metabolic myopathy with a broad clinical spectrum. Generalised muscle weakness combined…”
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Enzyme therapy for Pompe disease: from science to industrial enterprise by Reuser, Arnold, Van den Hout, Hannerieke, Bijvoet, Agnes, Kroos, Marian, Verbeet, Martin, Van der Ploeg, Ans

“…Pompe disease or glycogen storage disease type II (OMIM 232300) is a metabolic myopathy with a broad clinical spectrum. Generalised muscle weakness combined…”
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Reconstitution of the Type-1 Active Site of the H145G/A Variants of Nitrite Reductase by Ligand Insertion by Wijma, Hein J, Boulanger, Martin J, Molon, Annamaria, Fittipaldi, Maria, Huber, Martina, Murphy, Michael E. P, Verbeet, Martin Ph, Canters, Gerard W

“…Variants of the copper-containing nitrite reductase (NiR) of Alcaligenes faecalis S6 were constructed by site-directed mutagenesis, by which the C-terminal…”
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Calorimetric and spectroscopic investigations of the thermal denaturation of wild type nitrite reductase by Stirpe, Andrea, Guzzi, Rita, Wijma, Hein, Verbeet, Martin Ph, Canters, Gerard W., Sportelli, Luigi

“…Nitrite reductase (NiR) is a multicopper protein, with a trimeric structure containing two types of copper site: type 1 is present in each subunit whereas type…”
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A model for the thermal unfolding of amicyanin by La, Rosa Carmelo, Milardi, Danilo, Grasso, Domenico M, Verbeet, Martin P, Canters, Gerard W, Sportelli, Luigi, Guzzi, Rita

“…In the present study the thermal unfolding of amicyanin has been addressed using differential scanning calorimetry, fluorescence emission, optical density,…”
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Protein Film Voltammetry of Copper-Containing Nitrite Reductase Reveals Reversible Inactivation by Wijma, Hein J, Jeuken, Lars J. C, Verbeet, Martin Ph, Armstrong, Fraser A, Canters, Gerard W

“…The Cu-containing nitrite reductase from Alcaligenes faecalis S-6 catalyzes the one-electron reduction of nitrite to nitric oxide (NO). Electrons enter the…”
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Towards Protein Field-Effect Transistors: Report and Model of a Prototype by Maruccio, G., Biasco, A., Visconti, P., Bramanti, A., Pompa, P. P., Calabi, F., Cingolani, R., Rinaldi, R., Corni, S., Di Felice, R., Molinari, E., Verbeet, M. P., Canters, G. W.

“…A protein field‐effect transistor (Pro‐FET) based on the blue‐copper protein azurins (see Figure) and operating at room temperature and ambient pressure is…”
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Protonation of a Histidine Copper Ligand in Fern Plastocyanin by Hulsker, Rinske, Mery, Annabelle, Thomassen, Ellen A, Ranieri, Antonio, Sola, Marco, Verbeet, Martin Ph, Kohzuma, Takamitsu, Ubbink, Marcellus

“…Plastocyanin is a small blue copper protein that shuttles electrons as part of the photosynthetic redox chain. Its redox behavior is changed at low pH as a…”
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Thermal stability effects of removing the type-2 copper ligand His306 at the interface of nitrite reductase subunits by Stirpe, Andrea, Sportelli, Luigi, Wijma, Hein, Verbeet, Martin Ph, Guzzi, Rita

“…Nitrite reductase (NiR) is a highly stable trimeric protein, which denatures via an intermediate, N(3)<--(k)-->U(3)--(k)-->F (N-native, U-unfolded and…”
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Role of the Surface-Exposed and Copper-Coordinating Histidine in Blue Copper Proteins:  The Electron-Transfer and Redox-Coupled Ligand Binding Properties of His117Gly Azurin by Jeuken, Lars J. C, van Vliet, Pieter, Verbeet, Martin Ph, Camba, Raul, McEvoy, James P, Armstrong, Fraser A, Canters, Gerard W

“…In many reduced blue copper proteins the C-terminal surface-exposed active-site histidine protonates at low pH and dissociates from the Cu atom. In this state,…”
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A Rearranging Ligand Enables Allosteric Control of Catalytic Activity in Copper-containing Nitrite Reductase by Wijma, Hein J., MacPherson, Iain, Alexandre, Maxime, Diederix, Rutger E.M., Canters, Gerard W., Murphy, Michael E.P., Verbeet, Martin Ph

“…In Cu-containing nitrite reductase from Alcaligenes faecalis S-6 the axial methionine ligand of the type-1 site was replaced (M150G) to make the copper ion…”
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Generalized glycogen storage and cardiomegaly in a knockout mouse model of Pompe disease by BIJVOET, A. G. A, VAN DE KAMP, E. H. M, VAN DER PLOEG, A. T, KROOS, M. A, DING, J.-H, YANG, B. Z, VISSER, P, BAKKER, C. E, VERBEET, M. P, OOSTRA, B. A, REUSER, A. J. J

“…Glycogen storage disease type II (GSDII; Pompe disease), caused by inherited deficiency of acid alpha-glucosidase, is a lysosomal disorder affecting heart and…”
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Thermal stability of wild type and disulfide bridge containing mutant of poplar plastocyanin by Guzzi, Rita, Andolfi, Laura, Cannistraro, Salvatore, Verbeet, Martin Ph, Canters, Gerard W., Sportelli, Luigi

“…A comparative study of the thermal stability of wild type poplar plastocyanin and of a mutant form containing a disulfide bridge between residues 21 and 25 was…”
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Effects of Dimerization on Protein Electron Transfer by van Amsterdam, Irene M. C., Ubbink, Marcellus, Jeuken, Lars J. C., Verbeet, Martin Ph, Einsle, Oliver, Messerschmidt, Albrecht, Canters, Gerard W.

“…In order to investigate the relationship between the rate of protein–protein electron transfer and the structure of the association complex, a dimer of the…”
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