Search Results - "Veranth, John"

ZnO Particulate Matter Requires Cell Contact for Toxicity in Human Colon Cancer Cells by Moos, Philip J, Chung, Kevin, Woessner, David, Honeggar, Matthew, Cutler, N. Shane, Veranth, John M

“…There is ongoing concern regarding the toxicity of nanoparticles with sizes less than 100 nm as compared to larger particles of the same nominal substance. Two…”
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Cytokine responses of human lung cells (BEAS-2B) treated with micron-sized and nanoparticles of metal oxides compared to soil dusts by Veranth, John M, Kaser, Erin G, Veranth, Martha M, Koch, Michael, Yost, Garold S

“…The induction of cytokines by airway cells in vitro has been widely used to assess the effects of ambient and occupational particles. This study measured…”
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Activation of Transient Receptor Potential Ankyrin‑1 (TRPA1) in Lung Cells by Wood Smoke Particulate Material by Shapiro, Darien, Deering-Rice, Cassandra E, Romero, Erin G, Hughen, Ronald W, Light, Alan R, Veranth, John M, Reilly, Christopher A

“…Cigarette smoke, diesel exhaust, and other combustion-derived particles activate the calcium channel transient receptor potential ankyrin-1 (TRPA1), causing…”
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Differential Activation of TRPA1 by Diesel Exhaust Particles: Relationships between Chemical Composition, Potency, and Lung Toxicity by Deering-Rice, Cassandra E, Memon, Tosifa, Lu, Zhenyu, Romero, Erin G, Cox, James, Taylor-Clark, Thomas, Veranth, John M, Reilly, Christopher A

“…Diesel exhaust particulate (DEP) causes pulmonary irritation and inflammation, which can exacerbate asthma and other diseases. These effects may arise from the…”
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Activation of TRPV3 by Wood Smoke Particles and Roles in Pneumotoxicity by Deering-Rice, Cassandra E, Nguyen, Nam, Lu, Zhenyu, Cox, James E, Shapiro, Darien, Romero, Erin G, Mitchell, Virginia K, Burrell, Katherine L, Veranth, John M, Reilly, Christopher A

“…Wood/biomass smoke particulate materials (WBSPM) are pneumo­toxic, but the mechanisms by which these materials affect lung cells are not fully understood. We…”
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Activation of Transient Receptor Potential Ankyrin-1 by Insoluble Particulate Material and Association with Asthma by Deering-Rice, Cassandra E, Shapiro, Darien, Romero, Erin G, Stockmann, Chris, Bevans, Tatjana S, Phan, Quang M, Stone, Bryan L, Fassl, Bernhard, Nkoy, Flory, Uchida, Derek A, Ward, Robert M, Veranth, John M, Reilly, Christopher A

“…Inhaled irritants activate transient receptor potential ankyrin-1 (TRPA1), resulting in cough, bronchoconstriction, and inflammation/edema. TRPA1 is also…”
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Electrophilic Components of Diesel Exhaust Particles (DEP) Activate Transient Receptor Potential Ankyrin-1 (TRPA1): A Probable Mechanism of Acute Pulmonary Toxicity for DEP by Deering-Rice, Cassandra E, Romero, Erin G, Shapiro, Darien, Hughen, Ronald W, Light, Alan R, Yost, Garold S, Veranth, John M, Reilly, Christopher A

“…Inhalation of environmental particulate matter (PM) is correlated with adverse health effects in humans, but gene products that couple detection with cellular…”
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Transient receptor potential vanilloid-1 (TRPV1) is a mediator of lung toxicity for coal fly ash particulate material by Deering-Rice, Cassandra E, Johansen, Mark E, Roberts, Jessica K, Thomas, Karen C, Romero, Erin G, Lee, Jeewoo, Yost, Garold S, Veranth, John M, Reilly, Christopher A

“…Environmental particulate matter (PM) pollutants adversely affect human health, but the molecular basis is poorly understood. The ion channel transient…”
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Characterization of Transient Receptor Potential Vanilloid-1 (TRPV1) Variant Activation by Coal Fly Ash Particles and Associations with Altered Transient Receptor Potential Ankyrin-1 (TRPA1) Expression and Asthma by Deering-Rice, Cassandra E., Stockmann, Chris, Romero, Erin G., Lu, Zhenyu, Shapiro, Darien, Stone, Bryan L., Fassl, Bernhard, Nkoy, Flory, Uchida, Derek A., Ward, Robert M., Veranth, John M., Reilly, Christopher A.

“…Transient receptor potential (TRP) channels are activated by environmental particulate materials. We hypothesized that polymorphic variants of transient…”
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Increased transcription of cytokine genes in human lung epithelial cells through activation of a TRPM8 variant by cold temperatures by Sabnis, Ashwini S, Reilly, Christopher A, Veranth, John M, Yost, Garold S

“…Recognition of temperature is a critical element of sensory perception and allows mammals to evaluate both their external environment and internal status. The…”
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Responses of human cells to ZnO nanoparticles: a gene transcription study by Moos, Philip J, Olszewski, Kyle, Honeggar, Matthew, Cassidy, Pamela, Leachman, Sancy, Woessner, David, Cutler, N Shane, Veranth, John M

“…The gene transcript profile responses to metal oxide nanoparticles was studied using human cell lines derived from the colon and skin tumors. Much of the…”
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Activation of Human Transient Receptor Potential Melastatin-8 (TRPM8) by Calcium-Rich Particulate Materials and Effects on Human Lung Cells by Lamb, John G, Romero, Erin G, Lu, Zhenyu, Marcus, Seychelle K, Peterson, Hannah C, Veranth, John M, Deering-Rice, Cassandra E, Reilly, Christopher A

“…To better understand how adverse health effects are caused by exposure to particulate materials, and to develop preventative measures, it is important to…”
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Combustion Aerosols: Factors Governing Their Size and Composition and Implications to Human Health by Lighty, JoAnn Slama, Veranth, John M., Sarofim, Adel F.

“…Particulate matter (PM) emissions from stationary combustion sources burning coal, fuel oil, biomass, and waste, and PM from internal combustion (IC) engines…”
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Detection, separation, and quantification of unlabeled silica nanoparticles in biological media using sedimentation field-flow fractionation by Tadjiki, Soheyl, Assemi, Shoeleh, Deering, Cassandra E., Veranth, John M., Miller, Jan D.

“…A rapid, high-resolution methodology for characterization, separation, and quantification of unlabeled inorganic nanoparticles extracted from biological media,…”
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Quantification of cerivastatin toxicity supports organismal performance assays as an effective tool during pharmaceutical safety assessment by Gaukler, Shannon M., Ruff, James S., Galland, Tessa, Underwood, Tristan K., Kandaris, Kirstie A., Liu, Nicole M., Morrison, Linda C., Veranth, John M., Potts, Wayne K.

“…A major problem in pharmaceutical development is that adverse effects remain undetected during preclinical and clinical trials, but are later revealed after…”
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A novel method to detect unlabeled inorganic nanoparticles and submicron particles in tissue by sedimentation field-flow fractionation by Deering, Cassandra E, Tadjiki, Soheyl, Assemi, Shoeleh, Miller, Jan D, Yost, Garold S, Veranth, John M

“…A novel methodology to detect unlabeled inorganic nanoparticles was experimentally demonstrated using a mixture of nano-sized (70 nm) and submicron (250 nm)…”
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Computational Modeling of CO/CO2 Ratio Inside Single Char Particles during Pulverized Coal Combustion by Krishnamoorthy, Gautham, Veranth, John M

“…A recently developed model was used to study the CO/CO2 ratio inside a burning pulverized coal particle, to better understand the effect of bulk gas…”
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Correlation of in Vitro Cytokine Responses with the Chemical Composition of Soil-Derived Particulate Matter by Veranth, John M., Moss, Tyler A., Chow, Judith C., Labban, Raed, Nichols, William K., Walton, John C., Watson, John G., Yost, Garold S.

“…We treated human lung epithelial cells, type BEAS-2B, with 10-80 μ g/ cm2 of dust from soils and road surfaces in the western United States that contained…”
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Acute Pulmonary and Systemic Effects of Inhaled Coal Fly Ash in Rats: Comparison to Ambient Environmental Particles by Smith, Kevin R., Veranth, John M., Kodavanti, Urmila P., Aust, Ann E., Pinkerton, Kent E.

“…Although primary particle emissions of ash from coal-fired power plants are well controlled, coal fly ash (CFA) can still remain a significant fraction of the…”
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Effects of cell type and culture media on Interleukin-6 secretion in response to environmental particles by Veranth, John M., Cutler, N. Shane, Kaser, Erin G., Reilly, Christopher A., Yost, Garold S.

“…Cultured lung cells provide an alternative to animal exposures for comparing the effects of different types of air pollution particles. Studies of particulate…”
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