Search Results - "Vera, M. S"

Artemia species: An Important Tool to Screen General Toxicity Samples by Ntungwe N, Epole, Domínguez-Martín, Eva M, Roberto, Amilcar, Tavares, Joana, Isca, Vera M S, Pereira, Paula, Cebola, Maria-João, Rijo, Patrícia

“…Medicinal plants are a good source of novel therapeutic drugs, due to the phytochemicals present. Artemia, commonly known as brine shrimp, is a tiny halophilic…”
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Extraction optimization and reactivity of 7α-acetoxy-6β-hydroxyroyleanone and ability of its derivatives to modulate PKC isoforms by Isca, Vera M. S., Bangay, Gabrielle, Princiotto, Salvatore, Saraíva, Lucília, dos Santos, Daniel J. V. A., García-Sosa, Alfonso T., Rijo, Patrícia

“…Protein kinase C is a family of kinases that play important roles in carcinogenesis. Medicinal plants from Plectranthus spp. (Lamiaceae) are a well-known…”
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Anticancer Effects of Abietane Diterpene 7α-Acetoxy-6β-hydroxyroyleanone from Plectranthus grandidentatus and Its Semi-Synthetic Analogs: An In Silico Computational Approach by Isca, Vera M S, Sitarek, Przemysław, Merecz-Sadowska, Anna, Małecka, Magdalena, Owczarek, Monika, Wieczfińska, Joanna, Zajdel, Radosław, Nowak, Paweł, Rijo, Patricia, Kowalczyk, Tomasz

“…The abietane diterpenoid 7α-acetoxy-6β-hydroxyroyleanone (Roy) isolated from demonstrates cytotoxicity across numerous cancer cell lines. To potentiate…”
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Exploring the Anticancer Potential of Semisynthetic Derivatives of 7α-Acetoxy-6β-hydroxyroyleanone from Plectranthus sp.: An In Silico Approach by Merecz-Sadowska, Anna, Isca, Vera M S, Sitarek, Przemysław, Kowalczyk, Tomasz, Małecka, Magdalena, Zajdel, Karolina, Zielińska-Bliźniewska, Hanna, Jęcek, Mariusz, Rijo, Patricia, Zajdel, Radosław

“…The diterpene 7α-acetoxy-6β-hydroxyroyleanone isolated from demonstrates promising antibacterial, anti-inflammatory and anticancer properties. However, its…”
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Glyphosate input modifies microbial community structure in clear and turbid freshwater systems by Pizarro, H, Vera, M. S, Vinocur, A, Pérez, G, Ferraro, M, Menéndez Helman, R. J, dos Santos Afonso, M

“…Since it was commercially introduced in 1974, glyphosate has been one of the most commonly used herbicides in agriculture worldwide, and there is growing…”
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Lipophilic profile of the edible halophyte Salicornia ramosissima by ISCA, Vera M. S, SECA, Ana M. L, PINTO, Diana C. G. A, SILVA, Helena, SILVA, Artur M. S

“…Salicornia ramosissima J. Woods is considered, in the Iberian Peninsula and France, a gourmet product. Nevertheless, is one of the less studied Salicornia…”
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Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCδ Activator by Bessa, Cláudia, Loureiro, Joana B, Barros, Matilde, Isca, Vera M S, Sardão, Vilma A, Oliveira, Paulo J, Bernardino, Raquel L, Herman-de-Sousa, Carina, Costa, Maria Adelina, Correia-de-Sá, Paulo, Alves, Marco G, Rijo, Patrícia, Saraiva, Lucília

“…Metabolic reprogramming is a central hub in tumor development and progression. Therefore, several efforts have been developed to find improved therapeutic…”
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Diterpenoids from Plectranthus spp. as Potential Chemotherapeutic Agents via Apoptosis by Śliwiński, Tomasz, Sitarek, Przemysław, Skała, Ewa, M. S. Isca, Vera, Synowiec, Ewelina, Kowalczyk, Tomasz, Bijak, Michał, Rijo, Patrícia

“…Plectranthus spp. is widely known for its medicinal properties and bioactive metabolites. The cytotoxic and genotoxic properties of the four known abietane…”
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In Vitro Antimicrobial Activity of Isopimarane-Type Diterpenoids by Isca, Vera M S, Andrade, Joana, Fernandes, Ana Sofia, Paixão, Paulo, Uriel, Clara, Gómez, Ana María, Duarte, Noélia, Rijo, Patrícia

“…The antimicrobial evaluation of twelve natural and hemisynthetic isopimarane diterpenes are reported. The compounds were evaluated against a panel of…”
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Charting the course of Physiology within the post-Bologna European higher education area: Insights from Portugal by Rodrigues, Luis Monteiro, Guerreiro, Iris, Isca, Vera M S, Gregório, João

“…The future of physiology has been a recurrent concern for physiologists and Physiological Societies within post-Bologna Europe and the European Higher…”
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Glycyrrhizic Acid Nanoparticles Subside the Activity of Methicillin-Resistant Staphylococcus aureus by Suppressing PBP2a by Rijo, Patricia, Abuamara, Tamer M M, Ali Lashin, Lashin Saad, Kamar, Sherif A, Isca, Vera M S, Mohammed, Tahseen S, Abdrabo, Mohamed S M, Amin, Mohamed A, Abd El Maksoud, Ahmed I, Hassan, Amr

“…and methicillin-resistant (MRSA) are classified as high-risk infections that can lead to death, particularly among older individuals. Nowadays, plant…”
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Activity to Breast Cancer Cell Lines of Different Malignancy and Predicted Interaction with Protein Kinase C Isoforms of Royleanones by Isca, Vera M S, Sencanski, Milan, Filipovic, Nenad, Dos Santos, Daniel J V A, Čipak Gašparović, Ana, Saraíva, Lucília, Afonso, Carlos A M, Rijo, Patrícia, García-Sosa, Alfonso T

“…Plants have been used for centuries to treat several illnesses. The genus has a vast variety of species that has allowed the isolation of cytotoxic compounds…”
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Molecular Docking Studies of Royleanone Diterpenoids from Plectranthus spp. as P‑Glycoprotein Inhibitors by Isca, Vera M. S, Ferreira, Ricardo J, Garcia, Catarina, Monteiro, Carlos M, Dinic, Jelena, Holmstedt, Suvi, André, Vânia, Pesic, Milica, dos Santos, Daniel J. V. A, Candeias, Nuno R, Afonso, Carlos A. M, Rijo, Patrícia

“…The development of multidrug resistance (MDR) is a major cause of failure in cancer chemotherapy. Several abietane diterpenes with antitumoral activities have…”
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Preliminary Phytochemical Analysis and Evaluation of the Biological Activity of Leonotis nepetifolia (L.) R. Br Transformed Roots Extracts Obtained through Rhizobium rhizogenes-Mediated Transformation by Kowalczyk, Tomasz, Merecz-Sadowska, Anna, Rijo, Patricia, Isca, Vera M. S., Picot, Laurent, Wielanek, Marzena, Śliwiński, Tomasz, Sitarek, Przemysław

“…According to the present knowledge, this is the first report on establishing transformed root cultures of Leonotis nepetifolia after Rhizobium…”
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Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors by Garcia, Catarina, Isca, Vera M S, Pereira, Filipe, Monteiro, Carlos M, Ntungwe, Epole, Sousa, Francisco, Dinic, Jelena, Holmstedt, Suvi, Roberto, Amílcar, Díaz-Lanza, Ana, Reis, Catarina P, Pesic, Milica, Candeias, Nuno R, Ferreira, Ricardo J, Duarte, Noélia, Afonso, Carlos A M, Rijo, Patrícia

“…Cancer is among the leading causes of death worldwide. One of the most challenging obstacles in cancer treatment is multidrug resistance (MDR). Overexpression…”
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Biological Activity of 6,7-Dehydroxyroyleanone and Derivatives Obtained from Plectranthus aliciae (Codd) A.J.Paton by Filipe, Márcia S., Domínguez-Martín, Eva M., Pires, Tânia C. S. P., Finimundy, Tiane C., Melgar, Bruno, Mandim, Filipa, Isca, Vera M. S., Pereira, Raquel, Teixidó-Trujillo, Silvia, Capote, Natalia A., Nikolić, Milan, Filipović, Nenad, Díaz-Lanza, Ana M., Figueiredo, Ana Cristina, Barros, Lillian, Rijo, Patrícia

“…The Plectranthus genus (Lamiaceae) is known to be rich in abietane diterpenes. The bioactive 6,7-dehydroxyroyleanone (DHR, 1) was previously isolated from…”
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NPHS2 mutations account for only 15% of nephrotic syndrome cases by Guaragna, Mara Sanches, Lutaif, Anna Cristina G B, Piveta, Cristiane S C, Souza, Marcela L, de Souza, Suéllen R, Henriques, Taciane B, Maciel-Guerra, Andréa T, Belangero, Vera M S, Guerra-Junior, Gil, De Mello, Maricilda P

“…Nephrotic syndrome is traditionally classified on the basis of the response to standard steroid treatment. Mutations in more than 24 genes have been associated…”
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NPHS1 gene mutations confirm congenital nephrotic syndrome in four Brazilian cases: A novel mutation is described by Guaragna, Mara S., Cleto, Thaís Lira, Souza, Marcela Lopes, Lutaif, Anna Cristina G.B., de Castro, Luiz Cláudio Gonçalves, Penido, Maria Goretti Moreira Guimarães, Maciel-Guerra, Andréa T., Belangero, Vera M.S., Guerra-Junior, Gil, De Mello, Maricilda P.

“…Aim Autosomal recessive mutations in NPHS1 gene are a common cause of congenital nephrotic syndrome (CNS). The disorder is characterized by massive proteinuria…”
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Rebound increases in chemokines by CXCR2 antagonist in breast cancer can be prevented by PKCδ and PKCε activators by Erin, Nuray, Tavşan, Esra, Akdeniz, Özlem, Isca, Vera M.S., Rijo, Patricia

“…Activation of CXCR2 by chemokines such as CXCL1 and CXCL2 increases aggressiveness of breast cancer, inducing chemoresistance, hence CXCR2 antagonists are in…”
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Freshwater dissolved oxygen dynamics: changes due to glyphosate, 2,4-D, and their mixture, both under clear and turbid-organic conditions by Lozano, V. L., Miranda, C. E., Vinocur, A. L., Sabio y García, C. A., Vera, M. S., González, C., Wolansky, M. J., Pizarro, H. N.

“…To evaluate the effect of glyphosate, 2,4-D, and their combination on daily dissolved oxygen saturation percentage (DO%) in freshwater, two separate outdoor…”
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