Search Results - "Vera, Andrés M."
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High force catch bond mechanism of bacterial adhesion in the human gut
Published in Nature communications (28-08-2020)“…Bacterial colonization of the human intestine requires firm adhesion of bacteria to insoluble substrates under hydrodynamic flow. Here we report the molecular…”
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2
Engineering an artificial catch bond using mechanical anisotropy
Published in Nature communications (08-04-2024)“…Catch bonds are a rare class of protein-protein interactions where the bond lifetime increases under an external pulling force. Here, we report how…”
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3
Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions
Published in Nature communications (02-03-2024)“…Abnormal trinucleotide repeat expansions alter protein conformation causing malfunction and contribute to a significant number of incurable human diseases…”
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4
Single-molecule dynamic structural biology with vertically arranged DNA on a fluorescence microscope
Published in Nature methods (08-11-2024)“…The intricate interplay between DNA and proteins is key for biological functions such as DNA replication, transcription and repair. Dynamic nanoscale…”
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Common features at the start of the neurodegeneration cascade
Published in PLoS biology (01-05-2012)“…Amyloidogenic neurodegenerative diseases are incurable conditions with high social impact that are typically caused by specific, largely disordered proteins…”
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Impact of scaffoldin mechanostability on cellulosomal activity
Published in Biomaterials science (07-07-2020)“…Lignocellulose is the most abundant renewable carbon source in the biosphere. However, the main bottleneck in its conversion to produce second generation…”
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Direct Identification of Protein-Protein Interactions by Single-Molecule Force Spectroscopy
Published in Angewandte Chemie (02-11-2016)“…Single‐molecule force spectroscopy based on atomic force microscopy (AFM‐SMFS) has allowed the measurement of the intermolecular forces involved in…”
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Direct Identification of Protein-Protein Interactions by Single-Molecule Force Spectroscopy
Published in Angewandte Chemie International Edition (02-11-2016)“…Single‐molecule force spectroscopy based on atomic force microscopy (AFM‐SMFS) has allowed the measurement of the intermolecular forces involved in…”
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The Nanomechanics of Neurotoxic Proteins Reveals Common Features at the Start of the Neurodegeneration Cascade
Published in Biophysical journal (31-01-2012)Get full text
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10
Acute Aortic Syndrome of Ascending Thoracic Aorta
Published in JACC. Case reports (01-12-2020)“…Treatment of ascending aorta disease is surgical; however, some series have evaluated the effectiveness of endovascular treatment. We report the case of a…”
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