Search Results - "Ver Donck, K."

Nucleoside transport inhibition and fMLP-stimulated whole blood luminescence by Ver Donck, K L, Verheyen, W J, Van Belle, H

“…Adenosine (ADO) has a pharmacological profile which makes it an interesting 'drug' to handle many of the problems arising with ischemia and reperfusion. In…”
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Structural interpretation of the amino acid sequence of a second domain from the Artemia covalent polymer globin by MOENS, L, VAN HAUWAERT, M.-L, DE SMET, K, VER DONCK, K, VAN DE PEER, Y, VAN BEEUMAN, J, WODAK, S, ALARD, P, TROTMAN, C

“…Artemia has a complex extracellular hemoglobin of Mr 260,000 comprising two globin chains (Mr 130,000) each of which is a polymer of eight covalently linked…”
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Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. Implications for its future role in cardioprotection by Rongen, G A, Smits, P, Ver Donck, K, Willemsen, J J, De Abreu, R A, Van Belle, H, Thien, T

“…In 12 healthy male volunteers (27-53 yr), a placebo-controlled randomized double blind cross-over trial was performed to study the effect of the intravenous…”
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The implications of non-linear red blood cell partitioning for the pharmacokinetics and pharmacodynamics of the nucleoside transport inhibitor draflazine by SNOECK, E, JACQMIN, P, HEYKANTS, J, VAN PEER, A, DANHOF, M, VER DONCK, K, VAN BELLE, H, WOESTENBORGHS, R, CRABBE, R, VAN GOOL, R, DUPONT, A

“…1. Draflazine, a nucleoside transport inhibitor, was administered as a 15 min i.v. infusion of 2.5 mg to eight healthy male subjects. Plasma and whole blood…”
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Population analysis of the non linear red blood cell partitioning and the concentration‐effect relationship of draflazine following various infusion rates by Snoeck, E., Piotrovskij, V., Jacqmin, P., Van Peer, A., Danhof, M., Ver Donck, K., Woestenborghs, R., Van Belle, H., Van Bortel, L., Van Gool, R., Dupont, A. G., Heykants, J.

“…Aims To investigate the impact of the specific red blood cell binding on the pharmacokinetics and pharmacodynamics of the nucleoside transport inhibitor…”
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Role of nucleoside transport inhibition and endogenous adenosine in prevention of catecholamine induced death in rabbits by Van Belle, H, Ver Donck, K, Verheyen, W

“…R 75,231, a potent and specific nucleoside transport inhibitor, largely prevents cardiac damage and death in catecholamine challenged rabbits. The major…”
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Physiological red blood cell kinetic model to explain the apparent discrepancy between adenosine breakdown inhibition and nucleoside transporter occupancy of draflazine by Snoeck, E, Ver Donck, K, Jacqmin, P, Van Belle, H, Dupont, A G, Van Peer, A, Danhof, M

“…A physiological red blood cell (RBC) kinetic model is proposed for the adenosine (ADO) transport into erythrocytes and its subsequent intracellular deamination…”
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A.264 Draflazine Inhibits red blood cell adenosine transport during CPB by Verborgh, C., D'haese, J., Ver Donck, K., Van Gool, R., Dupont, A., Camu, F.

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The implications of non‐linear red blood cell partitioning for the pharmacokinetics and pharmacodynamics of the nucleoside transport inhibitor draflazine by SNOECK, E., JACQMIN, P., PEER, A., DANHOF, M., DONCK, K., BELLE, H., WOESTENBORGHS, R., CRABBÉ, R., GOOL, R., DUPONT, A., HEYKANTS, J.

“…1 Draflazine, a nucleoside transport inhibitor, was administered as a 15 min i.v. infusion of 2.5 mg to eight healthy male subjects. Plasma and whole blood…”
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Comparison of the existing nucleoside transport inhibitors: in vitro and in vivo data by Van Belle, H, Wynants, J, Ver Donck, K

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Prevention of catecholamine-induced cardiac damage and death with a nucleoside transport inhibitor by Van Belle, H, Verheyen, W, Ver Donck, K, Janssen, P A, Robertson, J I

“…The effect of a potent and specific nucleoside transport inhibitor, R 75,231, on catecholamine-induced cardiac toxicity has been studied in rabbits…”
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High-grade nucleoside transport inhibition stimulates ventilation in humans by Rongen, G A, Smits, P, Bootsma, G, Ver Donck, K, de Vries, A, Thien, T

“…In 6 healthy male volunteers a placebo-controlled, double-blind, randomized, crossover trial was done to assess the effect of 1, 2, 4, and 6 mg of draflazine,…”
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Purine metabolism in the heart. Strategies for protection against myocardial ischaemia by Ver Donck, K

“…Adenosine has recently received much attention for the protection it provides against the deleterious effects of ischaemia reperfusion. Whenever the demand for…”
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