Search Results - "Venza, Mario"
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Cellular Mechanisms of Oxidative Stress and Action in Melanoma
Published in Oxidative medicine and cellular longevity (01-01-2015)“…Most melanomas occur on the skin, but a small percentage of these life-threatening cancers affect other parts of the body, such as the eye and mucous…”
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Genistein reduces proliferation of EP3-expressing melanoma cells through inhibition of PGE2-induced IL-8 expression
Published in International immunopharmacology (01-09-2018)“…Genistein, a natural isoflavone found in soybean products, is considered as a powerful anti-cancer agent, although the involved mechanisms are not fully…”
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miR-92a-3p and MYCBP2 are involved in MS-275-induced and c-myc-mediated TRAIL-sensitivity in melanoma cells
Published in International immunopharmacology (01-11-2016)“…Increasing evidence has demonstrated that in several tumors c-myc acts either as an oncogène or as a proapoptotic agent, depending on binding partner…”
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4
Neutrophils Directly Recognize Group B Streptococci and Contribute to Interleukin-1β Production during Infection
Published in PloS one (10-08-2016)“…Previous studies have shown that the pro-inflammatory cytokine IL-1β has a crucial role in host defenses against group B streptococcus (GBS), a frequent human…”
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Role of Toll-like receptor 13 in innate immune recognition of group B streptococci
Published in Infection and immunity (01-12-2014)“…Murine Toll-like receptor 13 (TLR13), an endosomal receptor that is not present in humans, is activated by an unmethylated motif present in the large ribosomal…”
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Heavy Metals and Epigenetic Alterations in Brain Tumors
Published in Current genomics (01-12-2014)“…Heavy metals and their derivatives can cause various diseases. Numerous studies have evaluated the possible link between exposure to heavy metals and various…”
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Epidrugs in the Immunotherapy of Cutaneous and Uveal Melanoma
Published in Anti-cancer agents in medicinal chemistry (01-02-2017)“…Epigenetic modifications can affect numerous mechanisms used by neoplastic cells to evade immune control. In melanoma epigenetic defects, caused by…”
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The overriding of TRAIL resistance by the histone deacetylase inhibitor MS-275 involves c-myc up-regulation in cutaneous, uveal, and mucosal melanoma
Published in International immunopharmacology (01-09-2015)“…Malignant melanoma is a highly aggressive tumor which may occur in the skin, eye, and mucous membranes. The prognosis of melanoma remains poor in spite of…”
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Rapid profiling of the antigen regions recognized by serum antibodies using massively parallel sequencing of antigen-specific libraries
Published in PloS one (04-12-2014)“…There is a need for techniques capable of identifying the antigenic epitopes targeted by polyclonal antibody responses during deliberate or natural…”
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Role of Genetics and Epigenetics in Mucosal, Uveal, and Cutaneous Melanomagenesis
Published in Anti-cancer agents in medicinal chemistry (01-01-2016)“…Melanoma prevalently occurs on parts of the body that have been overexposed to the sun. However, it can also originate in the nervous system, eye and mucous…”
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Essential role of interleukin-1 signaling in host defenses against group B streptococcus
Published in mBio (09-09-2014)“…Signal transduction via MyD88, an adaptor protein engaged by the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) family receptors, has a crucial…”
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Epitope Mapping of a Monoclonal Antibody Directed against Neisserial Heparin Binding Antigen Using Next Generation Sequencing of Antigen-Specific Libraries
Published in PloS one (10-08-2016)“…We explore here the potential of a newly described technology, which is named PROFILER and is based on next generation sequencing of gene-specific lambda…”
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PGE2 induces interleukin-8 derepression in human astrocytoma through coordinated DNA demethylation and histone hyperacetylation
Published in Epigenetics (01-11-2012)“…We have recently reported that in astrocytoma cells the expression of interleukin-8 (IL-8) is upregulated by prostaglandin E2 (PGE2). Unfortunately, the exact…”
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Epigenetic Effects of Cadmium in Cancer: Focus on Melanoma
Published in Current genomics (01-12-2014)“…Cadmium is a highly toxic heavy metal, which has a destroying impact on organs. Exposure to cadmium causes severe health problems to human beings due to its…”
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Innovative therapeutic strategies in the treatment of brain metastases
Published in International Journal of Molecular Sciences (22-01-2013)“…Brain metastases (BM) are the most common intracranial tumors and their incidence is increasing. Untreated brain metastases are associated with a poor…”
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Involvement of epimutations in meningioma
Published in Brain tumor pathology (01-07-2015)“…Epimutations are heritable and reversible cell markers, which can influence cell function going beyond the effects of DNA mutations. They result from multiple…”
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Salivary Histamine Level as a Predictor of Periodontal Disease in Type 2 Diabetic and Non‐Diabetic Subjects
Published in Journal of periodontology (1970) (01-09-2006)“…Background: Some previous investigations underscored the role of histamine in periodontal disease, especially in diabetic patients, but the behavior of this…”
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FOXE1 gene mutation screening by multiplex PCR/DHPLC in CHARGE syndrome and syndromic and non-syndromic cleft palate
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (19-05-2006)“…Denaturing high-performance liquid chromatography (DHPLC) has established itself as one of the most powerful tools for DNA variation screening. FOXE1, a highly…”
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Class I-specific histone deacetylase inhibitor MS-275 overrides TRAIL-resistance in melanoma cells by downregulating c-FLIP
Published in International immunopharmacology (01-08-2014)“…Tumor-necrosis factor-related apoptosis-inducing ligand (TRAIL) has selective killing effect toward malignant cells; however some human melanomas are…”
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Epigenetic regulation of p14 and p16 expression in cutaneous and uveal melanoma
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-03-2015)Get full text
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