Search Results - "Ventura, Bianca Helena"
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Standardizing CRISPR-Cas13 knockdown technique to investigate the role of cdh2 gene in pituitary development through growth hormone expression and transcription factors
Published in Frontiers in endocrinology (Lausanne) (10-10-2024)“…Congenital hypopituitarism (CH) is characterized by the deficiency of pituitary hormones. Among CH patients, 85% lack a molecular diagnosis. Whole Exome…”
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Zebrafish embryo sensitivity test as in vivo platform to anti-Shiga toxin compound screening
Published in Brazilian journal of microbiology (01-09-2020)“…Shiga toxin-producing Escherichia coli (STEC) pathotype secretes two types of AB 5 cytotoxins (Stx1 and Stx2), responsible for complications such as…”
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Zebrafish as an alternative animal model in human and animal vaccination research
Published in Laboratory animal research (07-05-2020)“…Much of medical research relies on animal models to deepen knowledge of the causes of animal and human diseases, as well as to enable the development of…”
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Doxorubicin-loaded pH-sensitive micelles: A promising alternative to enhance antitumor activity and reduce toxicity
Published in Biomedicine & pharmacotherapy (01-02-2021)“…[Display omitted] •Preparation, and characterization of pH-sensitive micelle composed of DSPE-PEG2000, oleic acid, and DOX.•The utilization of oleic acid is…”
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SARS-CoV-2 Nucleocapsid Protein is Associated With Lower Testosterone Levels: An Experimental Study
Published in Frontiers in physiology (03-06-2022)“…The ongoing COVID-19 pandemic represents an extra burden in the majority of public and private health systems worldwide beyond the most pessimistic…”
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MON-714 CRISPR / Cas9 Genomic Edition of the CDH2 Gene in Zebrafish Leads to Eye and Cardiac Malformation
Published in Journal of the Endocrine Society (08-05-2020)“…Abstract Introduction: The CDH2 gene encodes a transmembrane protein responsible for calcium-dependent cell-cell adhesion that participates in the process of…”
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MON-712 Restoration of Growth and Fertility in Zebrafish (Danio Rerio) Model with PROP1 Knockout Generated by CRISPR/Cas9 Genomic Editing
Published in Journal of the Endocrine Society (08-05-2020)“…Abstract Introduction: Hypopituitarism is defined as the deficiency of one or more pituitary hormones and can occur due to pathogenic allelic variants in…”
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Early brief treatment with losartan plus mycophenolate mofetil provides lasting renoprotection in a renal ablation model
Published in American journal of nephrology (01-01-2010)“…Inflammatory events antecede established renal injury in rats with 5/6 renal ablation (Nx), as indicated by the beneficial effects of early, uninterrupted…”
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