Search Results - "Venter, F."

Long-COVID : an evolving problem with an extensive impact by Mendelson, M, Nel, J, Blumberg, L, Madhi, S.A, Dryden, M, Stevens, W, Venter, F.W.D

“…Persistence of symptoms or development of new symptoms relating to SARS-CoV-2 infection late in the course of COVID-19 is an increasingly recognised problem…”
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Long-COVID: An evolving problem with an extensive impact by Mendelson, M, Nel, J, Blumberg, L, Madhi, S A, Dryden, M, Stevens, W, Venter, F W D

“…Persistence of symptoms or development of new symptoms relating to SARS-CoV-2 infection late in the course of COVID-19 is an increasingly recognised problem…”
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Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptase by Siedner, Mark J., Moorhouse, Michelle A., Simmons, Bryony, de Oliveira, Tulio, Lessells, Richard, Giandhari, Jennifer, Kemp, Stephen A., Chimukangara, Benjamin, Akpomiemie, Godspower, Serenata, Celicia M., Venter, Willem D. F., Hill, Andrew, Gupta, Ravindra K.

“…Little is known about the impact of pretreatment drug resistance (PDR) on the efficacy of second generation integrase inhibitors. We sequenced pretreatment…”
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Simplified clinical algorithm for identifying patients eligible for same-day HIV treatment initiation (SLATE): Results from an individually randomized trial in South Africa and Kenya by Rosen, Sydney, Maskew, Mhairi, Larson, Bruce A, Brennan, Alana T, Tsikhutsu, Isaac, Fox, Matthew P, Vezi, Lungisile, Bii, Margaret, Venter, Willem D F

“…The World Health Organization recommends "same-day" initiation of antiretroviral therapy (ART) for HIV patients who are eligible and ready. Identifying…”
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The best of both worlds: no apparent trade-off between immunity and reproduction in two group-living African mole-rat species by Wallace, K M E, Hart, Daniel W, Venter, F, van Vuuren, A K Janse, Bennett, N C

“…Co-operatively breeding mammals often exhibit a female reproductive skew and suppression of the subordinate non-breeding group members. According to…”
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Statement of support for Professor Glenda Gray and the principle of academic freedom of speech by Venter, Francois

“…As scientists, academics and policy experts, we are committed to being part of the complex policy response and debate on dealing with the epidemic of…”
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A clinical algorithm for same-day HIV treatment initiation in settings with high TB symptom prevalence in South Africa: The SLATE II individually randomized clinical trial by Maskew, Mhairi, Brennan, Alana T., Fox, Matthew P., Vezi, Lungisile, Venter, Willem D. F., Ehrenkranz, Peter, Rosen, Sydney

“…Introduction In its 2017 revision of the global guidelines for HIV care and treatment, the World Health Organization (WHO) called for rapid or same-day…”
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Comparison of Xpert MTB/RIF with other nucleic acid technologies for diagnosing pulmonary tuberculosis in a high HIV prevalence setting: a prospective study by Scott, Lesley E, McCarthy, Kerrigan, Gous, Natasha, Nduna, Matilda, Van Rie, Annelies, Sanne, Ian, Venter, Willem F, Duse, Adrian, Stevens, Wendy

“…The Xpert MTB/RIF (Cepheid) non-laboratory-based molecular assay has potential to improve the diagnosis of tuberculosis (TB), especially in HIV-infected…”
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Incidence and risk factors for the immune reconstitution inflammatory syndrome in HIV patients in South Africa: a prospective study by Murdoch, David M, Venter, Willem D F, Feldman, Charles, Van Rie, Annelies

“…To determine the incidence, clinical manifestations, risk factors and outcome of immune reconstitution inflammatory syndrome (IRIS) in South Africa…”
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Predictors of prolonged hospital stay in HIV-positive patients presenting to the emergency department by Laher, Abdullah E, Paruk, Fathima, Richards, Guy A, Venter, Willem D F

“…Prolonged hospitalization places a significant burden on healthcare resources. Compared to the general population, hospital length of stay (LOS) is generally…”
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WHO ART guidelines and beyond: Should CD4 count be a barrier to ART initiation by Venter, F

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Causes of death on antiretroviral therapy: a post-mortem study from South Africa by Wong, Emily B, Omar, Tanvier, Setlhako, Gosetsemang J, Osih, Regina, Feldman, Charles, Murdoch, David M, Martinson, Neil A, Bangsberg, David R, Venter, W D F

“…Mortality in the first months of antiretroviral therapy (ART) is a significant clinical problem in sub-Saharan Africa. To date, no post-mortem study has…”
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Virological suppression and clinical management in response to viremia in South African HIV treatment program: A multicenter cohort study by Hermans, Lucas E, Carmona, Sergio, Nijhuis, Monique, Tempelman, Hugo A, Richman, Douglas D, Moorhouse, Michelle, Grobbee, Diederick E, Venter, Willem D F, Wensing, Annemarie M J

“…Uptake of antiretroviral treatment (ART) is expanding rapidly in low- and middle-income countries (LMIC). Monitoring of virological suppression is recommended…”
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Electrocardiographic and echocardiographic abnormalities in urban African people living with HIV in South Africa by Roozen, Geert V T, Meel, Ruchika, Peper, Joyce, Venter, William D F, Barth, Roos E, Grobbee, Diederick E, Klipstein-Grobusch, Kerstin, Vos, Alinda G

“…Studies from high income countries report that HIV-positive people have an impaired systolic and diastolic cardiac function compared to HIV-negative people. It…”
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Pre-exposure Prophylaxis: The Delivery Challenge by Venter, Willem D F

“…HIV pre-exposure prophylaxis (PrEP), despite its efficacy, has been slow in uptake throughout the world. This article discusses the operational and service…”
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Cardiovascular disease risk in an urban African population: a cross-sectional analysis on the role of HIV and antiretroviral treatment by Vos, Alinda G, Hoeve, Klariska, Barth, Roos E, Peper, Joyce, Moorhouse, Michelle, Crowther, Nigel J, Venter, Willem D F, Grobbee, Diederick E, Bots, Michiel L, Klipstein-Grobusch, Kerstin

“…Life expectancy is increasing in the HIV-positive population and age-related non-communicable diseases, such as cardiovascular disease, (CVD) are seen more…”
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Intervention strategies to improve adherence to treatment for selected chronic conditions in sub‐Saharan Africa: a systematic review by Gumede, Siphamandla Bonga, Wit, John B. F., Venter, Willem D. F., Wensing, Annemarie M. J., Lalla‐Edward, Samanta Tresha

“…Introduction Evidence‐based intervention strategies to improve adherence among individuals living with chronic conditions are critical in ensuring better…”
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Population pharmacokinetics of tenofovir given as either tenofovir disoproxil fumarate or tenofovir alafenamide in an African population by Kawuma, Aida N., Wasmann, Roeland E., Sinxadi, Phumla, Sokhela, Simiso M., Chandiwana, Nomathemba, Venter, Willem D. F., Wiesner, Lubbe, Maartens, Gary, Denti, Paolo

“…Tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) are prodrugs of the nucleotide analogue tenofovir, which acts intracellularly to inhibit…”
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Evaluation of the Abbott m2000 RealTime Human Immunodeficiency Virus Type 1 (HIV-1) Assay for HIV Load Monitoring in South Africa Compared to the Roche Cobas AmpliPrep-Cobas Amplicor, Roche Cobas AmpliPrep-Cobas TaqMan HIV-1, and BioMerieux NucliSENS EasyQ HIV-1 Assays by Scott, Lesley E, Noble, Lara D, Moloi, Jackie, Erasmus, Linda, Venter, Willem D.F, Stevens, Wendy

“…The implementation of antiretroviral therapy demands the need for increased access to viral load (VL) monitoring. Newer real-time VL testing technologies are…”
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High incidence of latent tuberculous infection among South African health workers: an urgent call for action by McCarthy, K. M., Scott, L. E., Gous, N., Tellie, M., Venter, W. D. F., Stevens, W. S., Van Rie, A.

“…SETTING: In South Africa, health care workers (HCWs) are at two-fold greater risk of acquiring tuberculosis (TB) disease than the general population. Few…”
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