Search Results - "Venteicher, Andrew S."

Insulator dysfunction and oncogene activation in IDH mutant gliomas by Flavahan, William A., Drier, Yotam, Liau, Brian B., Gillespie, Shawn M., Venteicher, Andrew S., Stemmer-Rachamimov, Anat O., Suvà, Mario L., Bernstein, Bradley E.

“…An epigenetic mechanism in which gain-of-function IDH mutations promote gliomagenesis by disrupting chromosomal topology is presented, with IDH mutations…”
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TPP1 OB-Fold Domain Controls Telomere Maintenance by Recruiting Telomerase to Chromosome Ends by Zhong, Franklin L., Batista, Luis F.Z., Freund, Adam, Pech, Matthew F., Venteicher, Andrew S., Artandi, Steven E.

“…Telomere synthesis in cancer cells and stem cells involves trafficking of telomerase to Cajal bodies, and telomerase is thought to be recruited to telomeres…”
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Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq by Venteicher, Andrew S., Tirosh, Itay, Hebert, Christine, Yizhak, Keren, Neftel, Cyril, Filbin, Mariella G., Hovestadt, Volker, Escalante, Leah E., Shaw, McKenzie L., Rodman, Christopher, Gillespie, Shawn M., Dionne, Danielle, Luo, Christina C., Ravichandran, Hiranmayi, Mylvaganam, Ravindra, Mount, Christopher, Onozato, Maristela L., Nahed, Brian V., Wakimoto, Hiroaki, Curry, William T., Iafrate, A. John, Rivera, Miguel N., Frosch, Matthew P., Golub, Todd R., Brastianos, Priscilla K., Getz, Gad, Patel, Anoop P., Monje, Michelle, Cahill, Daniel P., Rozenblatt-Rosen, Orit, Louis, David N., Bernstein, Bradley E., Regev, Aviv, Suvà, Mario L.

“…Tumor subclasses differ according to the genotypes and phenotypes of malignant cells as well as the composition of the tumor microenvironment (TME). We…”
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Proteostatic Control of Telomerase Function through TRiC-Mediated Folding of TCAB1 by Freund, Adam, Zhong, Franklin L., Venteicher, Andrew S., Meng, Zhaojing, Veenstra, Timothy D., Frydman, Judith, Artandi, Steven E.

“…Telomere maintenance by telomerase is impaired in the stem cell disease dyskeratosis congenita and during human aging. Telomerase depends upon a complex…”
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A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis by Venteicher, Andrew S., Abreu, Eladio B., Meng, Zhaojing, McCann, Kelly E., Terns, Rebecca M., Veenstra, Timothy D., Terns, Michael P., Artandi, Steven E.

“…Telomerase is a ribonucleoprotein (RNP) complex that synthesizes telomere repeats in tissue progenitor cells and cancer cells. Active human telomerase consists…”
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Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly by Venteicher, Andrew S., Meng, Zhaojing, Mason, Philip J., Veenstra, Timothy D., Artandi, Steven E.

“…Telomerase is a multisubunit ribonucleoprotein (RNP) complex that adds telomere repeats to the ends of chromosomes. Three essential telomerase components have…”
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Role of immunotherapy in treatment refractory chordomas: review of current evidence by Alexander, A Yohan, Dhawan, Sanjay, Venteicher, Andrew S

“…Chordomas are aggressive tumors that are thought to arise from remnants of the embryological notochord. They can arise along the ventromedial aspect of the…”
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TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program by Choi, Jinkuk, Southworth, Lucinda K, Sarin, Kavita Y, Venteicher, Andrew S, Ma, Wenxiu, Chang, Woody, Cheung, Peggie, Jun, Sohee, Artandi, Maja K, Shah, Naman, Kim, Stuart K, Artandi, Steven E

“…Telomerase serves a critical role in stem cell function and tissue homeostasis. This role depends on its ability to synthesize telomere repeats in a manner…”
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TCAB1: Driving telomerase to Cajal bodies by Venteicher, Andrew S., Artandi, Steven E.

“…Telomerase supports the proliferation of progenitor cells and tumor cells by adding telomere repeats to chromosome ends.  The low abundance and restricted…”
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Comparison of peripheral leukocyte parameters in patients receiving conventionally and hypofractionated radiotherapy schemes for the treatment of newly diagnosed glioblastoma by Greenlund, Lindsey, Shanley, Ryan, Mulford, Kellen, Neil, Elizabeth C, Lawrence, Jessica, Arnold, Susan, Olin, Michael, Pluhar, G Elizabeth, Venteicher, Andrew S, Chen, Clark C, Ferreira, Clara, Reynolds, Margaret, Cho, L Chinsoo, Wilke, Christopher, Shoo, B Aika, Yuan, Jianling, Dusenbery, Kathryn, Kleinberg, Lawrence R, Terezakis, Stephanie A, Sloan, Lindsey

“…Treatment for glioblastomas, aggressive and nearly uniformly fatal brain tumors, provide limited long-term success. Immunosuppression by myeloid cells in both…”
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Rapid Intraoperative Molecular Characterization of Glioma by Shankar, Ganesh M, Francis, Joshua M, Rinne, Mikael L, Ramkissoon, Shakti H, Huang, Franklin W, Venteicher, Andrew S, Akama-Garren, Elliot H, Kang, Yun Jee, Lelic, Nina, Kim, James C, Brown, Loreal E, Charbonneau, Sarah K, Golby, Alexandra J, Sekhar Pedamallu, Chandra, Hoang, Mai P, Sullivan, Ryan J, Cherniack, Andrew D, Garraway, Levi A, Stemmer-Rachamimov, Anat, Reardon, David A, Wen, Patrick Y, Brastianos, Priscilla K, Curry, William T, Barker, 2nd, Fred G, Hahn, William C, Nahed, Brian V, Ligon, Keith L, Louis, David N, Cahill, Daniel P, Meyerson, Matthew

“…Conclusive intraoperative pathologic confirmation of diffuse infiltrative glioma guides the decision to pursue definitive neurosurgical resection. Establishing…”
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Endoscopic burr hole evacuation of an acute subdural hematoma by Codd, Patrick J, Venteicher, Andrew S, Agarwalla, Pankaj K, Kahle, Kristopher T, Jho, David H

“…Abstract Acute subdural hematoma evacuations frequently necessitate large craniotomies with extended operative times and high relative blood loss, which can…”
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Learning Curve Associated with ClearPoint Neuronavigation System: A Case Series by Taha, Birra R., Osswald, Christian R., Rabon, Matthew, Garcia, Carolina Sandoval, Guillaume, Daniel J., Wong, Xiao, Venteicher, Andrew S., Darrow, David P., Park, Michael C., McGovern, Robert A., Lam, Cornelius H., Chen, Clark C.

“…The ClearPoint neuronavigation system affords real-time magnetic resonance imaging (MRI) guidance during stereotactic procedures. While such information…”
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Early versus delayed postoperative radiotherapy for treatment of low-grade gliomas by Dhawan, Sanjay, Patil, Chirag G, Chen, Clark, Venteicher, Andrew S

“…This is an update of the review originally published in 2011 and first updated in 2015. In most people with low-grade gliomas (LGG), the primary treatment…”
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Anaplastic Meningioma of the Orbit by Rajjoub, Raneem D., Venteicher, Andrew S., Harrison, Andrew R.

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Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance by Liau, Brian B., Sievers, Cem, Donohue, Laura K., Gillespie, Shawn M., Flavahan, William A., Miller, Tyler E., Venteicher, Andrew S., Hebert, Christine H., Carey, Christopher D., Rodig, Scott J., Shareef, Sarah J., Najm, Fadi J., van Galen, Peter, Wakimoto, Hiroaki, Cahill, Daniel P., Rich, Jeremy N., Aster, Jon C., Suvà, Mario L., Patel, Anoop P., Bernstein, Bradley E.

“…Glioblastoma, the most common and aggressive malignant brain tumor, is propagated by stem-like cancer cells refractory to existing therapies. Understanding the…”
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Clinical features of brain metastasis from salivary gland tumors by Venteicher, Andrew S, Walcott, Brian P, Sheth, Sameer A, Snuderl, Matija, Patel, Anoop P, Curry, William T, Nahed, Brian V

“…Abstract Salivary gland tumors comprise a group of 24 tumor subtypes with a wide range of clinical behaviors and propensities for metastasis. Several…”
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Racial disparities in recommendations for surgical resection of primary brain tumours: a registry-based cohort analysis by Butterfield, John T, Golzarian, Sina, Johnson, Reid, Fellows, Emily, Dhawan, Sanjay, Chen, Clark C, Marcotte, Erin L, Venteicher, Andrew S

“…Disparities in treatment and outcomes disproportionately affect minority ethnic and racial populations in many surgical fields. Although substantial research…”
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Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma by Tirosh, Itay, Venteicher, Andrew S., Hebert, Christine, Escalante, Leah E., Patel, Anoop P., Yizhak, Keren, Fisher, Jonathan M., Rodman, Christopher, Mount, Christopher, Filbin, Mariella G., Neftel, Cyril, Desai, Niyati, Nyman, Jackson, Izar, Benjamin, Luo, Christina C., Francis, Joshua M., Patel, Aanand A., Onozato, Maristela L., Riggi, Nicolo, Livak, Kenneth J., Gennert, Dave, Satija, Rahul, Nahed, Brian V., Curry, William T., Martuza, Robert L., Mylvaganam, Ravindra, Iafrate, A. John, Frosch, Matthew P., Golub, Todd R., Rivera, Miguel N., Getz, Gad, Rozenblatt-Rosen, Orit, Cahill, Daniel P., Monje, Michelle, Bernstein, Bradley E., Louis, David N., Regev, Aviv, Suvà, Mario L.

“…A single sentence summarizing your paper (websum), which will appear online on the table of contents and in e-alerts, has been provided below. Please check…”
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PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response by Li, Jie, Kaneda, Megan M., Ma, Jun, Li, Ming, Shepard, Ryan M., Patel, Kunal, Koga, Tomoyuki, Sarver, Aaron, Furnari, Frank, Xu, Beibei, Dhawan, Sanjay, Ning, Jianfang, Zhu, Hua, Wu, Anhua, You, Gan, Jiang, Tao, Venteicher, Andrew S., Rich, Jeremy N., Glass, Christopher K., Varner, Judith A., Chen, Clark C.

“…Precision medicine in oncology leverages clinical observations of exceptional response. Toward an understanding of the molecular features that define this…”
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