Search Results - "Venteclef, N"

Early macrophage response to obesity encompasses Interferon Regulatory Factor 5 regulated mitochondrial architecture remodelling by Orliaguet, L., Ejlalmanesh, T., Humbert, A., Ballaire, R., Diedisheim, M., Julla, J. B., Chokr, D., Cuenco, J., Michieletto, J., Charbit, J., Lindén, D., Boucher, J., Potier, C., Hamimi, A., Lemoine, S., Blugeon, C., Legoix, P., Lameiras, S., Baudrin, L. G., Baulande, S., Soprani, A., Castelli, F. A., Fenaille, F., Riveline, J. P., Dalmas, E., Rieusset, J., Gautier, J. F., Venteclef, N., Alzaid, F.

“…Adipose tissue macrophages (ATM) adapt to changes in their energetic microenvironment. Caloric excess, in a range from transient to diet-induced obesity, could…”
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The oxysterol receptor LXRβ protects against DSS- and TNBS-induced colitis in mice by Jakobsson, T, Vedin, L-L, Hassan, T, Venteclef, N, Greco, D, D'Amato, M, Treuter, E, Gustafsson, J-Å, Steffensen, K R

“…We examined the function of the oxysterol receptors (LXRs) in inflammatory bowel disease (IBD) through studying dextran sodium sulfate (DSS)- and…”
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PO37 Dysregulation of SMRT/GPS2 Corepressor Complex Is Associated with Adipose Tissue Inflammation in Human Obesity by Toubal, A, Allili, R, Pelloux, V, Barsh, G, Clément, K, Treuter, E, Venteclef, N

“…Introduction Obesity has become a global epidemic and is one the most significant public health challenges of the 21st century. In recent years, more and more…”
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CO-31: Rab4b dans les lymphocytes T : un acteur important de l'homéostasie gluco-lipidique by Gilleron, J, Bouget, G, Vergoni, B, Jacquel, A, Venteclef, N, Tanti, J, Cormont, M

“…Introduction Lors de l'obésité, la résistance à l'insuline est un élément clef du développement du diabète de type 2. Les lymphocytes résidents du tissu…”
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P2141 La dérégulation du complexe répresseur SMRT/GPS2 induit l’inflammation adipocytaire dans l’obésité by Venteclef, N, Clément, K, Treuter, E, Toubal, A

“…Introduction De nombreuses études démontrent que l’inflammation du tissu adipeux est un des processus biologiques majoritairement perturbé. L’inflammation est…”
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CA-011: Le Vascular Endothelium Growth Factor (VEGF-A) est associé à l'insulinorésistance dans le diabète de type 2 by Nguewa, J, Lontchi-Yimagou, E, Ait Djoudi, M, Riveline, J, Boudou, P, Venteclef, N, Blondeau, B, Sobngwi, E, Gautier, J

“…Objectif Le vascular endothelial growth factor (VEGF) est une glycoprotéine dont le rôle est d'augmenter la perméabilité vasculaire et stimuler la croissance…”
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CO-09: Interferon Regulatory Factor-5 (irf5) orchestre la fibrogenèse hépatique by Alzaid, F, Hainault, I, Orliaguet, L, Ballaire, R, Mesdom, P, Lehuen, A, Paradis, V, Foufelle, F, Venteclef, N

“…Introduction Le facteur de transcription Interferon Regulatory Factor-5 (irf5) est connu pour exercer un rôle crucial dans la polarisation des macrophages…”
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PO16 Interferon Regulatory Factor-5 (IRF5) contrôle l’inflammation métabolique dans le diabète de type 2 by Alzaid, F, Dalmas, E, Toubal, A, Lebozec, K, Ancel, P, Cruciani-Guglielmacci, C, Foufelle, F, Poitou, C, Torcivia, A, Luquet, S, Aron-Wisnewsky, J, Clément, K, Udalova, I, Venteclef, N

“…Introduction Les maladies de l’obésité, comme le diabète, sont associés à l’accumulation de tissu adipeux dans la région intra-abdominale. Les mécanismes…”
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Transcriptional and epigenetic control of adipocyte remodeling during obesity by Barilla, Serena, Treuter, Eckardt, Venteclef, Nicolas

“…The rising prevalence of obesity over the past decades coincides with the rising awareness that a detailed understanding of both adipose tissue biology and…”
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Transcriptional repression in macrophages—basic mechanisms and alterations in metabolic inflammatory diseases by Treuter, Eckardt, Fan, Rongrong, Huang, Zhiqiang, Jakobsson, Tomas, Venteclef, Nicolas

“…Macrophage differentiation and signal responses are coordinated by closely linked transcriptional and epigenomic mechanisms that trigger gene expression. In…”
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Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation by Treuter, Eckardt, Venteclef, Nicolas

“…Nuclear receptors (NRs) exert crucial functions in controlling metabolism and inflammation by both positively and negatively regulating gene expression. Recent…”
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The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages by Huang, Zhiqiang, Liang, Ning, Goñi, Saioa, Damdimopoulos, Anastasios, Wang, Cheng, Ballaire, Raphaelle, Jager, Jennifer, Niskanen, Henri, Han, Hongya, Jakobsson, Tomas, Bracken, Adrian P., Aouadi, Myriam, Venteclef, Nicolas, Kaikkonen, Minna U., Fan, Rongrong, Treuter, Eckardt

“…While the role of transcription factors and coactivators in controlling enhancer activity and chromatin structure linked to gene expression is well…”
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Role of the nuclear receptor REV-ERB-Α in vascular calcification by Ferri, L., Bellengier, C., Julla, J.-B., Bongiovanni, A., Delhaye, S., Duhem, C., Thorel, Q., Hebras, A., Leriche, M., Ram, B., Bicharel, M., Amaouche, M., Mayeuf-Louchart, A., Sebti, Y., Tardivel, M., Venteclef, N., Staels, B., Gautier, J.-F., Pourcet, B., Duez, H.

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Metabolic nuclear receptor signaling and the inflammatory acute phase response by Venteclef, Nicolas, Jakobsson, Tomas, Steffensen, Knut R, Treuter, Eckardt

“…The acute phase response (APR) classically refers to the rapid reprogramming of gene expression and metabolism in response to inflammatory cytokine signaling…”
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Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes by Fan, Rongrong, Toubal, Amine, Goñi, Saioa, Drareni, Karima, Huang, Zhiqiang, Alzaid, Fawaz, Ballaire, Raphaelle, Ancel, Patricia, Liang, Ning, Damdimopoulos, Anastasios, Hainault, Isabelle, Soprani, Antoine, Aron-Wisnewsky, Judith, Foufelle, Fabienne, Lawrence, Toby, Gautier, Jean-Francois, Venteclef, Nicolas, Treuter, Eckardt

“…The co-repressor GPS2 acts in macrophages to regulate their activation in obesity-induced inflammation, and appropriate GPS2 function is required to maintain…”
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Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα by Liang, Ning, Damdimopoulos, Anastasius, Goñi, Saioa, Huang, Zhiqiang, Vedin, Lise-Lotte, Jakobsson, Tomas, Giudici, Marco, Ahmed, Osman, Pedrelli, Matteo, Barilla, Serena, Alzaid, Fawaz, Mendoza, Arturo, Schröder, Tarja, Kuiper, Raoul, Parini, Paolo, Hollenberg, Anthony, Lefebvre, Philippe, Francque, Sven, Van Gaal, Luc, Staels, Bart, Venteclef, Nicolas, Treuter, Eckardt, Fan, Rongrong

“…Obesity triggers the development of non-alcoholic fatty liver disease (NAFLD), which involves alterations of regulatory transcription networks and epigenomes…”
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GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRβ in the hepatic acute phase response by Venteclef, Nicolas, Jakobsson, Tomas, Ehrlund, Anna, Damdimopoulos, Anastasios, Mikkonen, Laura, Ellis, Ewa, Nilsson, Lisa-Mari, Parini, Paolo, Jänne, Olli A., Gustafsson, Jan-Åke, Steffensen, Knut R., Treuter, Eckardt

“…The orphan receptor LRH-1 and the oxysterol receptors LXRα and LXRβ are established transcriptional regulators of lipid metabolism that appear to control…”
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Genomic and epigenomic regulation of adipose tissue inflammation in obesity by Toubal, Amine, Treuter, Eckardt, Clément, Karine, Venteclef, Nicolas

“…Highlights • Nutrient excess leads to the expression of inflammatory molecules and the recruitment of immune cells. • Transcription factors control the…”
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Plasma Copeptin and Risk of Lower-Extremity Amputation in Type 1 and Type 2 Diabetes: Diabetes Care by Potier, L., Roussel, R., Marre, M., Bjornstad, P., Cherney, D. Z., El Boustany, R., Fumeron, F., Venteclef, N., Gautier, J. F., Hadjadj, S., Mohammedi, Kamel, Velho, G.

“…OBJECTIVE: Diabetes is the leading cause of nontraumatic lower-extremity amputations (LEAs). Identification of patients with foot ulcers at risk for amputation…”
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Editorial: Nuclear Receptors and Coregulators in Metabolism and Immunity by Fan, Rongrong, Pineda-Torra, Ines, Venteclef, Nicolas

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