Search Results - "Vennström, Bjorn"

International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: thyroid hormone receptors by Flamant, Frédéric, Baxter, John D, Forrest, Douglas, Refetoff, Samuel, Samuels, Herbert, Scanlan, Tom S, Vennström, Bjorn, Samarut, Jacques

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Thyroid Hormone Receptor β1 Acts as a Potent Suppressor of Tumor Invasiveness and Metastasis by MARTINEZ-IGLESIAS, Olaia, GARCIA-SILVA, Susana, TENBAUM, Stephan P, REGADERA, Javier, LARCHER, Fernando, PARAMIO, Jesus M, VENNSTRÖM, Bjorn, ARANDA, Ana

“…Abstract Loss of thyroid hormone receptors (TR) is a common feature in some tumors, although their role in tumor progression is currently unknown. We show here…”
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The Thyroid Hormone Receptor α1 Protein Is Expressed in Embryonic Postmitotic Neurons and Persists in Most Adult Neurons by Wallis, Karin, Dudazy, Susi, Hogerlinden, Max van, Nordström, Kristina, Mittag, Jens, Vennström, Björn

“…Thyroid hormone is essential for brain development where it acts mainly through the thyroid hormone receptor α1 (TRα1) isoform. However, the potential for the…”
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Adaptations of the Autonomous Nervous System Controlling Heart Rate Are Impaired by a Mutant Thyroid Hormone Receptor-α1 by Mittag, Jens, Davis, Benjamin, Vujovic, Milica, Arner, Anders, Vennström, Björn

“…Thyroid hormone has profound direct effects on cardiac function, but the hormonal interactions with the autonomic control of heart rate are unclear. Because…”
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Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor α1 by Warner, Amy, Rahman, Awahan, Solsjö, Peter, Gottschling, Kristina, Davis, Benjamin, Vennström, Björn, Arner, Anders, Mittag, Jens

“…Thyroid hormone is a major regulator of thermogenesis, acting both in peripheral organs and on central autonomic pathways. Mice heterozygous for a point…”
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3‐Iodothyroacetic acid lacks thermoregulatory and cardiovascular effects in vivo by Hoefig, Carolin S, Jacobi, Simon F, Warner, Amy, Harder, Lisbeth, Schanze, Nancy, Vennström, Björn, Mittag, Jens

“…Background and Purpose 3‐Iodothyronamine (3‐T1AM) is an endogenous thyroid hormone derivative reported to induce strong hypothermia and bradycardia within…”
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Thermoregulatory and Cardiovascular Consequences of a Transient Thyrotoxicosis and Recovery in Male Mice by Hoefig, Carolin S, Harder, Lisbeth, Oelkrug, Rebecca, Meusel, Moritz, Vennström, Björn, Brabant, Georg, Mittag, Jens

“…Thyroid hormones play a major role in body homeostasis, regulating energy expenditure and cardiovascular function. Given that obese people or athletes might…”
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Thyroid hormones regulate selenoprotein expression and selenium status in mice by Mittag, Jens, Behrends, Thomas, Hoefig, Carolin S, Vennström, Björn, Schomburg, Lutz

“…Impaired expression of selenium-containing proteins leads to perturbed thyroid hormone (TH) levels, indicating the central importance of selenium for TH…”
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Thyroid hormone is required for hypothalamic neurons regulating cardiovascular functions by Mittag, Jens, Lyons, David J, Sällström, Johan, Vujovic, Milica, Dudazy-Gralla, Susi, Warner, Amy, Wallis, Karin, Alkemade, Anneke, Nordström, Kristina, Monyer, Hannah, Broberger, Christian, Arner, Anders, Vennström, Björn

“…Thyroid hormone is well known for its profound direct effects on cardiovascular function and metabolism. Recent evidence, however, suggests that the hormone…”
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Serum copper as a novel biomarker for resistance to thyroid hormone by Mittag, Jens, Behrends, Thomas, Nordström, Kristina, Anselmo, Joao, Vennström, Björn, Schomburg, Lutz

“…Thyroid hormone action is mediated by the thyroid hormone receptors TRα1 and TRβ. Defects in TRβ lead to RTH (resistance to thyroid hormone) β, a syndrome…”
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Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor α1 by Sjögren, Maria, Alkemade, Anneke, Mittag, Jens, Nordström, Kristina, Katz, Abram, Rozell, Björn, Westerblad, Håkan, Arner, Anders, Vennström, Björn

“…Thyroid hormone, via its nuclear receptors TRα and TRβ, controls metabolism by acting locally in peripheral tissues and centrally by regulating sympathetic…”
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Regulation of Bile Acid Synthesis by the Nuclear Receptor Rev-erbα by Duez, Hélène, van der Veen, Jelske N, Duhem, Christian, Pourcet, Benoît, Touvier, Thierry, Fontaine, Coralie, Derudas, Bruno, Baugé, Eric, Havinga, Rick, Bloks, Vincent W, Wolters, Henk, van der Sluijs, Fjodor H, Vennström, Björn, Kuipers, Folkert, Staels, Bart

“…Background & Aims: Conversion into bile acids represents an important route to remove excess cholesterol from the body. Rev-erbα is a nuclear receptor that…”
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Depressed Thermogenesis but Competent Brown Adipose Tissue Recruitment in Mice Devoid of All Hormone-Binding Thyroid Hormone Receptors by Golozoubova, Valeria, Gullberg, Hjalmar, Matthias, Anita, Cannon, Barbara, Vennström, Björn, Nedergaard, Jan

“…We have examined the metabolic role of hormone-binding nuclear thyroid hormone receptors (TRs). Mice devoid of all hormone-binding TRs [TRα1(−/−)β(−/−)…”
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Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene by Pazirandeh, Ahmad, Sultana, Taranum, Mirza, Momina, Rozell, Björn, Hultenby, Kjell, Wallis, Karin, Vennström, Björn, Davis, Ben, Arner, Anders, Heuchel, Rainer, Löhr, Matthias, Philipson, Lennart, Sollerbrant, Kerstin

“…To determine the normal function of the Coxsackievirus and Adenovirus Receptor (CAR), a protein found in tight junctions and other intercellular complexes, we…”
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Functions of thyroid hormone receptors in mice by Forrest, D, Vennström, B

“…Thyroid hormone receptors (TRs) play a central role in mediating the actions of thyroid hormone in development and homeostasis in vertebrate species. The TRs…”
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A thyroid hormone receptor that is required for the development of green cone photoreceptors by Reh, Thomas A, Forrest, Douglas, Ng, Lily, Hurley, James B, Dierks, Blair, Srinivas, Maya, Saltó, Carmen, Vennström, Björn

“…Color vision is facilitated by distinct populations of cone photoreceptors in the retina. In rodents, cones expressing different opsin photopigments are…”
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Interference of a Mutant Thyroid Hormone Receptor α1 with Hepatic Glucose Metabolism by Vujovic, Milica, Nordström, Kristina, Gauthier, Karine, Flamant, Frédéric, Visser, Theo J, Vennström, Björn, Mittag, Jens

“…Mice expressing the mutant thyroid hormone receptor TRα1R384C, which has a 10-fold reduced affinity to the ligand T3, exhibit hypermetabolism due to an…”
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Locomotor Deficiencies and Aberrant Development of Subtype-Specific GABAergic Interneurons Caused by an Unliganded Thyroid Hormone Receptor α1 by Wallis, Karin, Sjögren, Maria, van Hogerlinden, Max, Silberberg, Gilad, Fisahn, André, Nordström, Kristina, Larsson, Lars, Westerblad, Håkan, Morreale de Escobar, Gabriela, Shupliakov, Oleg, Vennström, Björn

“…Thyroid hormone (TH) deficiency during development causes severe and permanent neuronal damage, but the primary insult at the tissue level has remained…”
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Deletion of the Thyroid Hormone Receptor α1 Prevents the Structural Alterations of the Cerebellum Induced by Hypothyroidism by Morte, Beatriz, Manzano, Jimena, Scanlan, Thomas, Vennström, Björn, Bernal, Juan

“…Thyroid hormone (T3) controls critical aspects of cerebellar development, such as migration of postmitotic granule cells and terminal differentiation of…”
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Increased depressive behaviour in mice harboring the mutant thyroid hormone receptor alpha 1 by Pilhatsch, Maximilian, Winter, Christine, Nordström, Kristina, Vennström, Björn, Bauer, Michael, Juckel, Georg

“…Clinical evidence indicates that hypothyroidism contributes to mood disorders. The present study tested if the mutant thyroid hormone receptor alpha 1 (TRα1)…”
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