Search Results - "Venkatesh, Tadmiri R."
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Gene Targeting Using a Promoterless Gene Trap Vector ("Targeted Trapping") Is an Efficient Method to Mutate a Large Fraction of Genes
Published in Proceedings of the National Academy of Sciences - PNAS (13-09-2005)“…A powerful tool for postgenomic analysis of mammalian gene function is gene targeting in mouse ES cells. We report that homologous recombination using a…”
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Regulation of glia number in Drosophila by Rap/Fzr, an activator of the anaphase-promoting complex, and Loco, an RGS protein
Published in Genetics (Austin) (01-04-2008)“…Glia mediate a vast array of cellular processes and are critical for nervous system development and function. Despite their immense importance in neurobiology,…”
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rap gene encodes Fizzy-related protein (Fzr) and regulates cell proliferation and pattern formation in the developing Drosophila eye-antennal disc
Published in Developmental biology (15-09-2005)“…The rap (retina aberrant in pattern) gene encodes the Fizzy-related protein (Fzr), which as an activator of the ubiquitin ligase complex; APC/C (anaphase…”
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Completion of Mitosis Requires Neither fzr/rap nor fzr2, a Male Germline-Specific Drosophila Cdh1 Homolog
Published in Current biology (20-08-2002)“…Proteolysis of mitotic regulators like securins and cyclins requires Fizzy(FZY)/Cdc20 and Fizzy-related(FZR)/Hct1/Cdh1 proteins [1–5]. Budding yeast Cdh1 acts…”
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rugose (rg), a Drosophila A kinase Anchor Protein, Is Required for Retinal Pattern Formation and Interacts Genetically With Multiple Signaling Pathways
Published in Genetics (Austin) (01-06-2002)“…In the developing Drosophila eye, cell fate determination and pattern formation are directed by cell-cell interactions mediated by signal transduction…”
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A GENETIC MODIFIER SCREEN IDENTIFIES MULTIPLE GENES THAT INTERACT WITH DROSOPHILA RAP FZR AND SUGGESTS NOVEL CELLULAR ROLES
Published in Journal of neurogenetics (01-07-2007)“…In the developing Drosophila eye, Rap Fzr plays a critical role in neural patterning by regulating the timely exit of precursor cells. Rap Fzr (Retina aberrant…”
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product of the prune locus of Drosophila is similar to mammalian GTPase-activating protein
Published in Nature (London) (03-10-1991)“…The X-linked prune (pn) eye-colour mutation of Drosophila melanogaster has a highly specific, complementary lethal interaction with the conditional dominant…”
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Role of glia in the organization and function of the visual nervous system of Drosophila
Published in Developmental biology (01-06-2007)Get full text
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Neuronal development in the Drosophila retina: monoclonal antibodies as molecular probes
Published in Cell (01-01-1984)“…The compound eye of D. melanogaster is a reiterative pattern of facets, each containing eight photoreceptor cells in a precise arrangement. This pattern is…”
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A GENETIC MODIFIER SCREEN IDENTIFIES MULTIPLE GENES THAT INTERACT WITH DROSOPHILA RAP/FZR AND SUGGESTS NOVEL CELLULAR ROLES
Published in Journal of neurogenetics (01-01-2007)Get full text
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Fused rhabdomeres (fur) in Drosophila: an eye mutation that alters rhabdomere morphology and retinal function
Published in Journal of neurogenetics (1991)“…In the Drosophila compound eye, the photoreceptor cells are organized in highly precise units, the ommatidia. In each photoreceptor cell, the primary…”
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Neuronal development in the Drosophila compound eye: Photoreceptor cells R1, R6, and R7 fail to differentiate in the retina aberrant in pattern (rap) mutant
Published in Journal of neurobiology (01-10-1996)“…The compound eye of Drosophila is a reiterated pattern of 800 unit eyes known as ommatidia. In each ommatidium there are eight photoreceptor neurons (R1–R8)…”
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