Search Results - "Venkataswamy, M."
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Chikungunya virus infection in human microglial C20 cells induces mitochondria-mediated apoptosis
Published in Frontiers in cellular and infection microbiology (23-04-2024)“…Chikungunya virus (CHIKV) infection is associated with acute clinical manifestations and chronic joint inflammation. CHIKV has emerged as a significant…”
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Prohibitin 1/2 mediates Dengue-3 entry into human neuroblastoma (SH-SY5Y) and microglia (CHME-3) cells
Published in Journal of biomedical science (19-04-2020)“…Very few studies have identified receptor molecules for dengue virus (DENV) on neural cells. This study was designed to identify putative receptor/(s) involved…”
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A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis
Published in Nature medicine (01-10-2011)“…New vaccine candidates are urgently needed for the control and prevention of Mycobacterium tuberculosis (Mtb) infection. Kari Sweeney and her colleagues now…”
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Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis
Published in The Journal of clinical investigation (01-08-2007)“…The inhibition of apoptosis of infected host cells is a well-known but poorly understood function of pathogenic mycobacteria. We show that inactivation of the…”
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Generation of induced pluripotent stem cell line, NIMHi013-A, from PBMCs of a female child with epilepsy carrying a novel SCN1A variant
Published in Stem cell research (01-12-2024)“…The iPSC line NIMHi013-A was generated from peripheral blood mononuclear cells of a paediatric patient with drug resistant epilepsy. The proband was found to…”
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Genomic epidemiology reveals multiple introductions and spread of SARS-CoV-2 in the Indian state of Karnataka
Published in PloS one (17-12-2020)“…Karnataka, a state in south India, reported its first case of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection on March 8, 2020, more…”
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Descriptive epidemiology of SARS-CoV-2 infection in Karnataka state, South India: Transmission dynamics of symptomatic vs. asymptomatic infections
Published in EClinicalMedicine (01-02-2021)“…The huge surge in COVID-19 cases in Karnataka state, India, during early phase of the pandemic especially following return of residents from other states and…”
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Direct incorporation of the NKT-cell activator α-galactosylceramide into a recombinant Listeria monocytogenes improves breast cancer vaccine efficacy
Published in British journal of cancer (11-11-2014)“…Background: Immune suppression in the tumour microenvironment remains a major limitation to successful immunotherapy of cancer. In the current study, we…”
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Mycobacterial membrane vesicles administered systemically in mice induce a protective immune response to surface compartments of Mycobacterium tuberculosis
Published in mBio (30-09-2014)“…Pathogenic and nonpathogenic species of bacteria and fungi release membrane vesicles (MV), containing proteins, polysaccharides, and lipids, into the…”
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Cellular Immune Responses to Live Attenuated Japanese Encephalitis (JE) Vaccine SA14-14-2 in Adults in a JE/Dengue Co-Endemic Area
Published in PLoS neglected tropical diseases (01-01-2017)“…Japanese encephalitis (JE) virus (JEV) causes severe epidemic encephalitis across Asia, for which the live attenuated vaccine SA14-14-2 is being used…”
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A Single Subset of Dendritic Cells Controls the Cytokine Bias of Natural Killer T Cell Responses to Diverse Glycolipid Antigens
Published in Immunity (Cambridge, Mass.) (16-01-2014)“…Many hematopoietic cell types express CD1d and are capable of presenting glycolipid antigens to invariant natural killer T cells (iNKT cells). However, the…”
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12
Single cell immune profiling of dengue virus patients reveals intact immune responses to Zika virus with enrichment of innate immune signatures
Published in PLoS neglected tropical diseases (01-03-2020)“…The genus Flavivirus contains many mosquito-borne human pathogens of global epidemiological importance such as dengue virus, West Nile virus, and Zika virus,…”
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Comparative sperm protein profiling in bulls differing in fertility and identification of phosphatidylethanolamine‐binding protein 4, a potential fertility marker
Published in Andrology (Oxford) (01-09-2017)“…Summary This study aimed to identify sperm proteomic signatures regulating sperm functions and fertility by: (i) comparing the sperm electrophoretic protein…”
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Cerebrospinal Fluid from Patients with Sporadic Amyotrophic Lateral Sclerosis Induces Degeneration of Motor Neurons Derived from Human Embryonic Stem Cells
Published in Molecular neurobiology (01-02-2019)“…Disease modeling has become challenging in the context of amyotrophic lateral sclerosis (ALS), as obtaining viable spinal motor neurons from postmortem patient…”
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15
Effect of span length on micromechanics of fracture under flexure load in CFRP composites
Published in Mechanics of advanced materials and structures (04-07-2018)“…Unidirectional (UD) and bidirectional (BD) woven carbon fiber reinforced plastic (CFRP) composites were tested under three-point flexure at different span…”
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A Rapid Fluorescence-Based Assay for Classification of iNKT Cell Activating Glycolipids
Published in Journal of the American Chemical Society (13-04-2011)“…Structural variants of α-galactosylceramide (αGC) that activate invariant natural killer T cells (iNKT cells) are being developed as potential immunomodulatory…”
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Lasing transition at 1.06 μm emission in Nd3+‐doped borate‐based tellurium calcium zinc niobium oxide glasses for high‐power solid‐state lasers
Published in Luminescence (Chichester, England) (01-08-2017)“…The spectroscopic properties of Tellurium Calcium Zinc Niobium oxide Borate (TCZNB) glasses of composition (in mol%) 10TeO2 + 15CaO + 5ZnO + 10 Nb2O5 + (60 –…”
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18
Lasing transition at 1.06 μm emission in Nd 3 + -doped borate-based tellurium calcium zinc niobium oxide glasses for high-power solid-state lasers
Published in Luminescence (Chichester, England) (01-08-2017)“…The spectroscopic properties of Tellurium Calcium Zinc Niobium oxide Borate (TCZNB) glasses of composition (in mol%) 10TeO + 15CaO + 5ZnO + 10 Nb O + (60 -…”
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19
Role of IS6110 uniplex PCR in the diagnosis of tuberculous meningitis: experience at a tertiary neurocentre
Published in The international journal of tuberculosis and lung disease (01-02-2007)“…SETTING: Tuberculous meningitis (TBM) is the commonest form of neurotuberculosis in the Indian subcontinent. Rapid laboratory confirmation of TBM is important…”
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Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents
Published in PloS one (17-12-2010)“…CD1d-restricted natural killer T cells with invariant T cell receptor α chains (iNKT cells) are a unique lymphocyte subset that responds to recognition of…”
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