Search Results - "Venkatachalem, Sathish"

3D Printability of Alginate-Carboxymethyl Cellulose Hydrogel by Habib, Ahasan, Sathish, Venkatachalem, Mallik, Sanku, Khoda, Bashir

“…Three-dimensional (3D) bio-printing is a revolutionary technology to reproduce a 3D functional living tissue scaffold in-vitro through controlled…”
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Hypoxia-Responsive, Polymeric Nanocarriers for Targeted Drug Delivery to Estrogen Receptor-Positive Breast Cancer Cell Spheroids by Mamnoon, Babak, Feng, Li, Froberg, Jamie, Choi, Yongki, Sathish, Venkatachalem, Mallik, Sanku

“…Uncontrolled cell growth, division, and lack of enough blood supply causes low oxygen content or hypoxia in cancerous tumor microenvironments. 17β-Estradiol…”
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Laser-capture microdissection of murine lung for differential cellular RNA analysis by Loganathan, Jagadish, Pandey, Roshni, Ambhore, Nilesh Sudhakar, Borowicz, Pawel, Sathish, Venkatachalem

“…The lung tissue contains a heterogeneous milieu of bronchioles, epithelial, airway smooth muscle (ASM), alveolar, and immune cell types. Healthy bronchiole…”
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Role of Differential Estrogen Receptor Activation in Airway Hyperreactivity and Remodeling in a Murine Model of Asthma by Ambhore, Nilesh Sudhakar, Kalidhindi, Rama Satyanarayana Raju, Loganathan, Jagadish, Sathish, Venkatachalem

“…Evidence suggests that airway hyperresponsiveness (AHR) is a characteristic feature of asthma. Epidemiological studies have confirmed that the severity of…”
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Network and co-expression analysis of airway smooth muscle cell transcriptome delineates potential gene signatures in asthma by Banerjee, Priyanka, Balraj, Premanand, Ambhore, Nilesh Sudhakar, Wicher, Sarah A., Britt, Rodney D., Pabelick, Christina M., Prakash, Y. S., Sathish, Venkatachalem

“…Airway smooth muscle (ASM) is known for its role in asthma exacerbations characterized by acute bronchoconstriction and remodeling. The molecular mechanisms…”
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Kisspeptin regulates airway hyperresponsiveness and remodeling in a mouse model of asthma by Borkar, Niyati A, Ambhore, Nilesh Sudhakar, Balraj, Premanand, Ramakrishnan, Yogaraj S, Sathish, Venkatachalem

“…Asthma is a multifactorial disease of origin characterized by airway hyperresponsiveness (AHR) and airway remodeling. Several pieces of evidence from other…”
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Estrogen receptor beta signaling inhibits PDGF induced human airway smooth muscle proliferation by Ambhore, Nilesh Sudhakar, Katragadda, Rathnavali, Raju Kalidhindi, Rama Satyanarayana, Thompson, Michael A., Pabelick, Christina M., Prakash, Y.S., Sathish, Venkatachalem

“…Airway smooth muscle (ASM) cell hyperplasia driven by persistent inflammation is a hallmark feature of remodeling in asthma. Sex steroid signaling in the lungs…”
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Role of Estrogen Receptors α and β in a Murine Model of Asthma: Exacerbated Airway Hyperresponsiveness and Remodeling in ERβ Knockout Mice by Kalidhindi, Rama Satyanarayana Raju, Ambhore, Nilesh Sudhakar, Bhallamudi, Sangeeta, Loganathan, Jagadish, Sathish, Venkatachalem

“…Epidemiological data suggests increased prevalence of asthma in females than males, suggesting a plausible role for sex-steroids, especially estrogen in the…”
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Kiss1 receptor knockout exacerbates airway hyperresponsiveness and remodeling in a mouse model of allergic asthma by Ambhore, Nilesh Sudhakar, Balraj, Premanand, Kumar, Ashish, Reza, Mohammad Irshad, Ramakrishnan, Yogaraj S, Tesch, Jacob, Lohana, Sahil, Sathish, Venkatachalem

“…In asthma, sex-steroids signaling is recognized as a critical regulator of disease pathophysiology. However, the paradoxical role of sex-steroids, especially…”
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Nanocarrier mediated entinostat and oxaliplatin combination therapy displayed enhanced efficacy against pancreatic cancer by Giri, Paras Mani, Kumar, Ashish, Salu, Philip, Sathish, Venkatachalem, Reindl, Katie, Mallik, Sanku, Layek, Buddhadev

“…Pancreatic cancer is the third leading cause of cancer-related death in the United States, with a 5-year survival rate of only 12%. The poor prognosis of…”
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Sex Steroids Effects on Asthma: A Network Perspective of Immune and Airway Cells by Borkar, Niyati A., Combs, Colin Kelly, Sathish, Venkatachalem

“…A multitude of evidence has suggested the differential incidence, prevalence and severity of asthma between males and females. A compilation of recent…”
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Brain-derived neurotrophic factor and airway fibrosis in asthma by Freeman, Michelle R, Sathish, Venkatachalem, Manlove, Logan, Wang, Shengyu, Britt, Jr, Rodney D, Thompson, Michael A, Pabelick, Christina M, Prakash, Y S

“…Airway remodeling in asthma driven by inflammation involves proliferation of epithelial cells and airway smooth muscle (ASM), as well as enhanced extracellular…”
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Glial‐derived neurotrophic factor in human airway smooth muscle by Bhallamudi, Sangeeta, Roos, Benjamin B., Teske, Jacob J., Wicher, Sarah A., McConico, Andrea, Pabelick, Christina, Sathish, Venkatachalem, Prakash, Y. S.

“…Airway smooth muscle (ASM) cells modulate the local airway milieu via production of inflammatory mediators and growth factors including classical…”
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2D Nanomaterial, Ti3C2 MXene-Based Sensor to Guide Lung Cancer Therapy and Management by Sadiq, Mahek, Pang, Lizhi, Johnson, Michael, Sathish, Venkatachalem, Zhang, Qifeng, Wang, Danling

“…Major advances in cancer control can be greatly aided by early diagnosis and effective treatment in its pre-invasive state. Lung cancer (small cell and…”
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Th1 cytokines synergize to change gene expression and promote corticosteroid insensitivity in pediatric airway smooth muscle by Jackson, Devine, Walum, Joshua, Banerjee, Priyanka, Lewis, Brandon W, Prakash, Y S, Sathish, Venkatachalem, Xu, Zhaohui, Britt, Jr, Rodney D

“…Corticosteroids remain a key therapy for treating children with asthma. Patients with severe asthma are insensitive, resistant, or refractory to…”
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Iminodibenzyl induced redirected COX-2 activity inhibits breast cancer progression by Shah, Harshit, Pang, Lizhi, Qian, Steven, Sathish, Venkatachalem

“…Knocking down delta-5-desaturase (D5D) by siRNA or shRNA is a promising strategy to achieve 8-hydroxyoctanoic acid (8-HOA) production for cancer inhibition…”
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EpCAM-Targeted 3WJ RNA Nanoparticle Harboring Delta-5-Desaturase siRNA Inhibited Lung Tumor Formation via DGLA Peroxidation by Pang, Lizhi, Shah, Harshit, Wang, Hongzhi, Shu, Dan, Qian, Steven Y., Sathish, Venkatachalem

“…Knocking down delta-5-desaturase (D5D) expression by D5D small interfering RNA (siRNA) has been reported that could redirect the cyclooxygenase-2…”
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Mechanisms of Cigarette Smoke Effects on Human Airway Smooth Muscle by Wylam, Mark E, Sathish, Venkatachalem, VanOosten, Sarah Kay, Freeman, Michelle, Burkholder, David, Thompson, Michael A, Pabelick, Christina M, Prakash, Y S

“…Cigarette smoke contributes to or exacerbates airway diseases such as asthma and COPD, where airway hyperresponsiveness and airway smooth muscle (ASM)…”
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Androgen Receptor-Mediated Regulation of Intracellular Calcium in Human Airway Smooth Muscle Cells by Kalidhindi, Rama Satyanarayana Raju, Katragadda, Rathnavali, Beauchamp, Kerri L, Pabelick, Christina M, Prakash, Y S, Sathish, Venkatachalem

“…With the prevalence of asthma being greater in women, detrimental effects of female sex steroids have been explored, but potential protective effects of…”
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Thymic stromal lymphopoietin in cigarette smoke-exposed human airway smooth muscle by Smelter, Dan F, Sathish, Venkatachalem, Thompson, Michael A, Pabelick, Christina M, Vassallo, Robert, Prakash, Y S

“…Thymic stromal lymphopoietin (TSLP) is a newly identified IL-7-like cytokine known to be expressed in airway biopsies of patients with asthma and chronic…”
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