Search Results - "Venkata Mallavadhani, Uppuluri"
-
1
Synthesis and antiproliferative activity of novel (+)- usnic acid analogues
Published in Journal of asian natural products research (02-06-2020)“…Twenty one novel (+)- usnic acid-based analogues belonging to three classes such as enamines, imines, and pyrazoles were synthesized. All the synthesized…”
Get full text
Journal Article -
2
Quantitative estimation of (-)-hinokinin, a trypanosomicidal marker in Piper cubeba, and some of its commercial formulations using HPLC-PDA
Published in Journal of pharmaceutical analysis (01-04-2015)“…The fruits of Piper cubeba have been used in Ayurvedic system of medicine for pain,tastelessness, painful urination and mouth diseases. Among its various…”
Get full text
Journal Article -
3
Antimicrobial Activity of Some Pentacyclic Triterpenes and Their Synthesized 3-O-Lipophilic Chains
Published in Biological & pharmaceutical bulletin (01-10-2004)“…The major metabolites of Diopsyros melanoxylon viz. amyrins and ursolic acid and their lipophilic 3-O-fatty acid ester chains (C12—C18), which are synthesized…”
Get full text
Journal Article -
4
Three New Pentacyclic Triterpenes and Some Flavonoids from the Fruits of an Indian Ayurvedic Plant Dendrophthoe falcata and Their Estrogen Receptor Binding Activity
Published in Chemical & pharmaceutical bulletin (01-05-2006)“…Extensive chromatographic screening of extracts of the fruits of the Indian Ayurvedic plant, Dendrophthoe falcata, resulted in the isolation of three new…”
Get full text
Journal Article -
5
Isolation, Synthesis and AChE Inhibitory Potential of Some Novel Cinnamyl Esters of Taraxerol, the Major Metabolite of the Mangrove Bruguiera cylindrica
Published in Chemistry & biodiversity (01-04-2018)“…Systematic chemical screening of the leaves of Bruguiera cylindrica, the tree mangrove of Rhizophoraceae family, afforded five single and pure compounds. The…”
Get full text
Journal Article -
6
Isolation, Chemical Modification, and Anticancer Activity of Major Metabolites of the Lichen Parmotrema mesotropum
Published in Chemistry of natural compounds (01-09-2019)“…Extensive chromatographic purification of the chloroform–methanol (1:1) extract of the lichen Parmotrema mesotropum led to the isolation of methyl hematommate…”
Get full text
Journal Article -
7
Synthesis of ring-C modified oleanolic acid derivatives and their cytotoxic evaluation
Published in Bioorganic chemistry (01-10-2016)“…[Display omitted] •Oleanolic acid ring-C was chemically modified.•Dienes, α,β-unsaturated ketone, saturated and unsaturated lactones were synthesized.•The…”
Get full text
Journal Article -
8
Synthesis of some novel orcinol based coumarin triazole hybrids with capabilities to inhibit RANKL-induced osteoclastogenesis through NF-κB signaling pathway
Published in Bioorganic chemistry (01-08-2018)“…[Display omitted] •Twenty-two novel orcinol based coumarin traizole hybrids were synthesized.•Synthesized compounds were evaluated for their anti-inflammatory…”
Get full text
Journal Article -
9
Synthesis and biological evaluation of some novel 1,2,3-triazole hybrids of myrrhanone B isolated from Commiphora mukul gum resin: Identification of potent antiproliferative leads active against prostate cancer cells (PC-3)
Published in European journal of medicinal chemistry (15-02-2020)“…A series of 28 novel 1,2,3-triazole hybrids of myrrhanone B have been designed and synthesized by employing regioselective Cu catalyzed Huisgen 1,3-dipolar…”
Get full text
Journal Article -
10
Novel triazole hybrids of myrrhanone C, a natural polypodane triterpene: Synthesis, cytotoxic activity and cell based studies
Published in European journal of medicinal chemistry (23-05-2016)“…The 3-keto functionality in ring A of myrrhanone C, a natural bicyclic triterpene has been chemically modified and synthesized 27 novel triazole hybrids…”
Get full text
Journal Article -
11
Development of Diagnostic Microscopic and Chemical Markers of Some Euphorbia Latexes
Published in Journal of integrative plant biology (01-09-2006)“…The latexes of the three Euphorbia species, namely E. antiquorum L., E. nerifolia L., and E. tirucalli L., are highly valued in the Indian system of medicine…”
Get full text
Journal Article -
12
Design, synthesis, anti-inflammatory, cytotoxic and cell based studies of some novel side chain analogues of myrrhanones A & B isolated from the gum resin of Commiphora mukul
Published in Bioorganic chemistry (01-02-2019)“…[Display omitted] •Myrrhanones A and B were isolated from gum resin of Commiphora mukul.•In total 29 novel analogues were synthesized from myrrhanones A and…”
Get full text
Journal Article -
13
Novel menadione hybrids: Synthesis, anticancer activity, and cell‐based studies
Published in Chemical biology & drug design (01-01-2018)“…A series of novel menadione‐based triazole hybrids were designed and synthesized by employing copper‐catalyzed azide‐alkyne cycloaddition (CuAAC). All the…”
Get full text
Journal Article -
14
Retinoic acid and evernyl-based menadione-triazole hybrid cooperate to induce differentiation of neuroblastoma cells
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-10-2023)“…Neuroblastoma arises when immature neural precursor cells do not mature into specialized cells. Although retinoic acid (RA), a pro-differentiation agent,…”
Get full text
Journal Article -
15
UPLC-Q–TOF-MS based studies to evaluate the effect of extraction methodology on the yield of 6-shogaol, a biomarker of Z. officinale
Published in Industrial crops and products (01-10-2013)“…•In order to generate 6-shogaol, the bio-active marker of Z. officinale (ginger) in large quantity, an highly efficient extraction method is desirable.•The…”
Get full text
Journal Article -
16
Synthesis of some novel methyl β-orsellinate based 3, 5-disubstituted isoxazoles and their anti-proliferative activity: Identification of potent leads active against MCF-7 breast cancer cell
Published in Bioorganic chemistry (01-12-2020)“…[Display omitted] •Sixteen novel methyl β-orsellinate based isoxazole hybrids synthesized.•Anti-proliferative activity of the hybrids was studied in a panel of…”
Get full text
Journal Article -
17
Synthesis and anti-inflammatory activity of some novel pyrimidine hybrids of myrrhanone A, a bicyclic triterpene of Commiphora mukul gum resin
Published in Monatshefte für Chemie (01-12-2017)“…Myrrhanone A (5 S ,8 R ,9 R ,10 R )-3-oxo-8,30-dihydroxypolypoda-13 E ,17 E ,21 E -triene), a bicyclic triterpene isolated from guggul ( Commiphora mukul Hook)…”
Get full text
Journal Article -
18
Synthesis and anticancer activity of novel fused pyrimidine hybrids of myrrhanone C, a bicyclic triterpene of Commiphora mukul gum resin
Published in Molecular diversity (01-11-2015)“…Myrrhanone C [8(R)-3-oxo-8-hydroxypolypoda-13E,17E,21-triene], a bicyclic triterpene isolated from the gum resin of Commiphora mukul , has been chemically…”
Get full text
Journal Article -
19
Synthesis and anticancer activity of some novel 5,6-fused hybrids of juglone based 1,4-naphthoquinones
Published in European journal of medicinal chemistry (18-08-2014)“…Six novel 5,6-fused hybrids such as dihydrobenzofuran-quinone (4a and 4b), benzofuran-quinone (5a and 5b) and chromene-quinone (6a and 6b) of juglone based…”
Get full text
Journal Article -
20
Synthesis of novel ring-A fused hybrids of oleanolic acid with capabilities to arrest cell cycle and induce apoptosis in breast cancer cells
Published in European journal of medicinal chemistry (03-03-2014)“…Six novel oleanolic acid ring-A fused hybrids (5–10) have been synthesized by employing a four step protocol with the introduction of benzylidene functionality…”
Get full text
Journal Article