Search Results - "Venkaiah, Betapudi"

Myosin II motor proteins with different functions determine the fate of lamellipodia extension during cell spreading by Betapudi, Venkaiah

“…Non-muscle cells express multiple myosin-II motor proteins myosin IIA, myosin IIB and myosin IIC transcribed from different loci in the human genome. Due to a…”
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Gene Therapy Leaves a Vicious Cycle by Goswami, Reena, Subramanian, Gayatri, Silayeva, Liliya, Newkirk, Isabelle, Doctor, Deborah, Chawla, Karan, Chattopadhyay, Saurabh, Chandra, Dhyan, Chilukuri, Nageswararao, Betapudi, Venkaiah

“…The human genetic code encrypted in thousands of genes holds the secret for synthesis of proteins that drive all biological processes necessary for normal life…”
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A novel pathway for human endothelial cell activation by antiphospholipid/anti-β2 glycoprotein I antibodies by Allen, Kristi L., Fonseca, Fabio V., Betapudi, Venkaiah, Willard, Belinda, Zhang, Jainwei, McCrae, Keith R.

“…Antiphospholipid Abs (APLAs) are associated with thrombosis and recurrent fetal loss. These Abs are primarily directed against phospholipid-binding proteins,…”
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Distinct roles of nonmuscle myosin II isoforms in the regulation of MDA-MB-231 breast cancer cell spreading and migration by BETAPUDI, Venkaiah, LICATE, Lucila S, EGELHOFF, Thomas T

“…Initial stages of tumor cell metastasis involve an epithelial-mesenchyme transition that involves activation of amoeboid migration and loss of cell-cell…”
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Editorial: TGF-β signalling pathways and their enigmatic role as a friend and foe in human health and diseases by Betapudi, Venkaiah, Patro, Birija Sankar, Saika, Shizuya, Rahaman, Shaik O

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Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells by Dulyaninova, Natalya G, House, Reniqua P, Betapudi, Venkaiah, Bresnick, Anne R

“…In mammalian nonmuscle cells, the mechanisms controlling the localized formation of myosin-II filaments are not well defined. To investigate the mechanisms…”
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The Homologous Region Sequence (hr1) of Autographa californica Multinucleocapsid Polyhedrosis Virus Can Enhance Transcription from Non-baculoviral Promoters in Mammalian Cells by Viswanathan, Priya, Venkaiah, Betapudi, Kumar, M. Senthil, Rasheedi, Sheeba, Vrati, Sudhanshu, Bashyam, Murali D., Hasnain, Seyed E.

“…The Autographa californica multinucleocapsid polyhedrosis virus homologous region sequence hr1 enhances transcription from the viral polyhedrin promoter in…”
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An Additional Copy of the Homologous Region (hr1) Sequence in the Autographa californica Multinucleocapsid Polyhedrosis Virus Genome Promotes Hyperexpression of Foreign Genes by Venkaiah, Betapudi, Viswanathan, Priya, Habib, Saman, Hasnain, Seyed E

“…The Autographa californica multinucleocapsid nuclear polyhedrosis virus genome contains nine homologous region (hr1, hr1a, hr2, hr2a, hr3, hr4a, hr4b, hr4c,…”
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Life without double-headed non-muscle myosin II motor proteins by Betapudi, Venkaiah

“…Non-muscle myosin II motor proteins (myosin IIA, myosin IIB, and myosin IIC) belong to a class of molecular motor proteins that are known to transduce cellular…”
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Generation of double gene disruptions in Dictyostelium discoideum using a single antibiotic marker selection by Betapudi, Venkaiah, Shoebotham, Karen, Egelhoff, Thomas T

“…Gene targeting is a powerful molecular genetic technique that has been widely used to understand specific gene function in vivo. This technique allows the…”
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Site-Specific Gene Delivery in vivo through Engineered Sendai Viral Envelopes by Ramani, Komal, Hassan, Quamarul, Venkaiah, Betapudi, Hasnain, Seyed E., Sarkar, Debi P.

“…Inspite of several stimulating developments in gene therapy, the formulation of a targeted gene delivery "vector" is still far from ideal. We have demonstrated…”
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Gene therapy delivering a paraoxonase 1 variant offers long-term prophylactic protection against nerve agents in mice by Betapudi, Venkaiah, Goswami, Reena, Silayeva, Liliya, Doctor, Deborah M, Chilukuri, Nageswararao

“…Chemical warfare nerve agents are organophosphorus chemical compounds that induce cholinergic crisis, leaving little or no time for medical intervention to…”
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Novel role for p56/Lck in regulation of endothelial cell survival and angiogenesis by Betapudi, Venkaiah, Shukla, Meenal, Alluri, Ravi, Merkulov, Sergei, McCrae, Keith R.

“…ABSTRACT Previous studies have demonstrated that cleaved high‐molecular‐weight kininogen (HKa) induces endothelial apoptosis and inhibits angiogenesis and have…”
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Induction of Endothelial Cell Apoptosis by Cleaved High Molecular Weight Kininogen Is Mediated Through a Lck and p53-Dependent Pathway by Betapudi, Venkaiah, McCrae, Keith R.

“…Abstract 3305 High molecular weight kininogen (HK) is an abundant plasma protein that serves as an important component of the intrinsic pathway of coagulation…”
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Analysis of Changes in Endothelial Cell Protein Expression and Phosphorylation Induced by Cleaved High Molecular Weight Kininogen by Betapudi, Venkaiah, McCrae, Keith R.

“…Abstract 5195 High molecular weight kininogen (HK) is an abundant plasma protein that functions as a critical cofactor in the kallikrein-kinin system. HK…”
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Anti-β2GPI antibodies stimulate endothelial cell microparticle release via a nonmuscle myosin II motor protein-dependent pathway by Betapudi, Venkaiah, Lominadze, George, Hsi, Linda, Willard, Belinda, Wu, Meifang, McCrae, Keith R.

“…The antiphospholipid syndrome is characterized by thrombosis and recurrent fetal loss in patients with antiphospholipid antibodies (APLAs). Most pathogenic…”
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A Novel Mechanism of Cellular Activation Mediated By Antiphospholipid Antibody-Induced Extracellular Vesicles by Wu, Meifang, Kundu, Suman, Betapudi, Venkaiah, McCrae, Keith R.

“…Introduction Antiphospholipid Syndrome (APS) is characterized by thrombosis and/or recurrent fetal loss in the presence of persistently elevated…”
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Regulation of the Tumor Microenvironment By High Molecular Weight Kininogen by Shukla, Meenal, Betapudi, Venkaiah, Alluri, Ravi Kumar, Merkulov, Sergei, Hale, James, Lathia, Justin, McCrae, Keith R.

“…Introduction High molecular weight kininogen (HK) is a central component of the contact activation and kallikrein-kinin systems. We have previously reported…”
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A Proteomic Study of Myosin II Motor Proteins during Tumor Cell Migration by Betapudi, Venkaiah, Gokulrangan, Giridharan, Chance, Mark R., Egelhoff, Thomas T.

“…Myosin II motor proteins play important roles in cell migration. Although myosin II filament assembly plays a key role in the stabilization of focal contacts…”
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The SRC Kinase Family Member Lymphocyte Specific Kinase (p56Lck) Regulates Endothelial Cell Proliferation and Survival by Betapudi, Venkaiah, Merkoulov, Sergei M., Kundu, Suman, Ji, Ou, Wu, Meifang, McCrae, Keith R.

“…Background and Objective: The Src family consists of Src, Lck (p56Lck), Fyn, Hck, Blk, Lyn, Fgr, Yes, and Yrk protein tyrosine kinases, which display cell and…”
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