Search Results - "Venit, Tomás"

β-actin dependent chromatin remodeling mediates compartment level changes in 3D genome architecture by Mahmood, Syed Raza, Xie, Xin, Hosny El Said, Nadine, Venit, Tomas, Gunsalus, Kristin C., Percipalle, Piergiorgio

“…β-actin is a crucial component of several chromatin remodeling complexes that control chromatin structure and accessibility. The mammalian Brahma-associated…”
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A dynamic actin-dependent nucleoskeleton and cell identity by Venit, Tomas, El Said, Nadine Hosny, Mahmood, Syed Raza, Percipalle, Piergiorgio

“…Actin is an essential regulator of cellular functions. In the eukaryotic cell nucleus, actin regulates chromatin as a bona fide component of chromatin…”
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Involvement of phosphatidylinositol 4,5-bisphosphate in RNA polymerase I transcription by Yildirim, Sukriye, Castano, Enrique, Sobol, Margarita, Philimonenko, Vlada V, Dzijak, Rastislav, Venit, Tomás, Hozák, Pavel

“…RNA polymerase I (Pol I) transcription is essential for the cell cycle, growth and protein synthesis in eukaryotes. In the present study, we found that…”
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Myosin VI regulates the spatial organisation of mammalian transcription initiation by Hari-Gupta, Yukti, Fili, Natalia, dos Santos, Ália, Cook, Alexander W., Gough, Rosemarie E., Reed, Hannah C. W., Wang, Lin, Aaron, Jesse, Venit, Tomas, Wait, Eric, Grosse-Berkenbusch, Andreas, Gebhardt, J. Christof M., Percipalle, Piergiorgio, Chew, Teng-Leong, Martin-Fernandez, Marisa, Toseland, Christopher P.

“…During transcription, RNA Polymerase II (RNAPII) is spatially organised within the nucleus into clusters that correlate with transcription activity. While this…”
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Specific nuclear localizing sequence directs two myosin isoforms to the cell nucleus in calmodulin-sensitive manner by Dzijak, Rastislav, Yildirim, Sukriye, Kahle, Michal, Novák, Petr, Hnilicová, Jarmila, Venit, Tomáš, Hozák, Pavel

“…Nuclear myosin I (NM1) was the first molecular motor identified in the cell nucleus. Together with nuclear actin, they participate in crucial nuclear events…”
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Assessing nanobody interaction with SARS-CoV-2 Nsp9 by Esposito, Gennaro, Hunashal, Yamanappa, Percipalle, Mathias, Fogolari, Federico, Venit, Tomas, Leonchiks, Ainars, Gunsalus, Kristin C, Piano, Fabio, Percipalle, Piergiorgio

“…The interaction between SARS-CoV-2 non-structural protein Nsp9 and the nanobody 2NSP90 was investigated by NMR spectroscopy using the paramagnetic perturbation…”
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Nuclear myosin I regulates cell membrane tension by Venit, Tomáš, Kalendová, Alžběta, Petr, Martin, Dzijak, Rastislav, Pastorek, Lukáš, Rohožková, Jana, Malohlava, Jakub, Hozák, Pavel

“…Plasma membrane tension is an important feature that determines the cell shape and influences processes such as cell motility, spreading, endocytosis and…”
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Nuclear actin and myosin in chromatin regulation and maintenance of genome integrity by Venit, Tomas, Mahmood, S Raza, Endara-Coll, Martin, Percipalle, Piergiorgio

“…Cytoskeletal proteins are beginning to be considered as key regulators of nuclear function. Among them, actin and myosin have been implicated in numerous…”
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Holography microscopy as an artifact-free alternative to phase-contrast by Pastorek, Lukáš, Venit, Tomáš, Hozák, Pavel

“…Artifact-free microscopic images represent a key requirement of multi-parametric image analysis in modern biomedical research. Holography microscopy (HM) is…”
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Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice by Venit, Tomas, Sapkota, Oscar, Abdrabou, Wael Said, Loganathan, Palanikumar, Pasricha, Renu, Mahmood, Syed Raza, El Said, Nadine Hosny, Sherif, Shimaa, Thomas, Sneha, Abdelrazig, Salah, Amin, Shady, Bedognetti, Davide, Idaghdour, Youssef, Magzoub, Mazin, Percipalle, Piergiorgio

“…Metabolic reprogramming is one of the hallmarks of tumorigenesis. Here, we show that nuclear myosin 1 (NM1) serves as a key regulator of cellular metabolism…”
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In Mitochondria β-Actin Regulates mtDNA Transcription and Is Required for Mitochondrial Quality Control by Xie, Xin, Venit, Tomas, Drou, Nizar, Percipalle, Piergiorgio

“…In eukaryotic cells, actin regulates both cytoplasmic and nuclear functions. However, whether actin-based structures are present in the mitochondria and are…”
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Author Correction: Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice by Venit, Tomas, Sapkota, Oscar, Abdrabou, Wael Said, Loganathan, Palanikumar, Pasricha, Renu, Mahmood, Syed Raza, El Said, Nadine Hosny, Sherif, Shimaa, Thomas, Sneha, Abdelrazig, Salah, Amin, Shady, Bedognetti, Davide, Idaghdour, Youssef, Magzoub, Mazin, Percipalle, Piergiorgio

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Tools for visualization of phosphoinositides in the cell nucleus by Kalasova, Ilona, Fáberová, Veronika, Kalendová, Alžběta, Yildirim, Sukriye, Uličná, Lívia, Venit, Tomáš, Hozák, Pavel

“…Phosphoinositides (PIs) are glycerol-based phospholipids containing hydrophilic inositol ring. The inositol ring is mono-, bis-, or tris-phosphorylated…”
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The nuclear activity of the actin‐binding Moesin protein is necessary for gene expression in Drosophila by Bajusz, Csaba, Kristó, Ildikó, Abonyi, Csilla, Venit, Tomáš, Vedelek, Viktor, Lukácsovich, Tamás, Farkas, Attila, Borkúti, Péter, Kovács, Zoltán, Bajusz, Izabella, Marton, Annamária, Vizler, Csaba, Lipinszki, Zoltán, Sinka, Rita, Percipalle, Piergiorgio, Vilmos, Péter

“…Ezrin–Radixin–Moesin (ERM) proteins play an essential role in the cytoplasm by cross‐linking actin filaments with plasma membrane proteins. Research has…”
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Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus by Venit, Tomáš, Dzijak, Rastislav, Kalendová, Alžběta, Kahle, Michal, Rohožková, Jana, Schmidt, Volker, Rülicke, Thomas, Rathkolb, Birgit, Hans, Wolfgang, Bohla, Alexander, Eickelberg, Oliver, Stoeger, Tobias, Wolf, Eckhard, Yildirim, Ali Önder, Gailus-Durner, Valérie, Fuchs, Helmut, de Angelis, Martin Hrabě, Hozák, Pavel

“…Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results…”
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Focal Adhesion Protein Vinculin Is Required for Proper Meiotic Progression during Mouse Spermatogenesis by Petrusová, Jana, Havalda, Robert, Flachs, Petr, Venit, Tomáš, Darášová, Alžběta, Hůlková, Lenka, Sztacho, Martin, Hozák, Pavel

“…The focal adhesion protein Vinculin (VCL) is ascribed to various cytoplasmic functions; however, its nuclear role has so far been ambiguous. We observed that…”
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Nuclear myosin 1 activates p21 gene transcription in response to DNA damage through a chromatin-based mechanism by Venit, Tomas, Semesta, Khairunnisa, Farrukh, Sannia, Endara-Coll, Martin, Havalda, Robert, Hozak, Pavel, Percipalle, Piergiorgio

“…Nuclear myosin 1 (NM1) has been implicated in key nuclear functions. Together with actin, it has been shown to initiate and regulate transcription, it is part…”
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Transcriptional Profiling Reveals Ribosome Biogenesis, Microtubule Dynamics and Expression of Specific lncRNAs to be Part of a Common Response to Cell-Penetrating Peptides by Venit, Tomas, Dowaidar, Moataz, Gestin, Maxime, Mahmood, Syed Raza, Langel, Ülo, Percipalle, Piergiorgio

“…Cell-penetrating peptides (CPPs) are short peptides that are able to efficiently penetrate cellular lipid bilayers. Although CPPs have been used as carriers in…”
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Journey to the Center of the Cell: Cytoplasmic and Nuclear Actin in Immune Cell Functions by Record, Julien, Saeed, Mezida B, Venit, Tomas, Percipalle, Piergiorgio, Westerberg, Lisa S

“…Actin cytoskeletal dynamics drive cellular shape changes, linking numerous cell functions to physiological and pathological cues. Mutations in actin regulators…”
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Involvement of PIP2 in RNA Polymerase I transcription by Yildirim, Sukriye, Castano, Enrique, Sobol, Margarita, Philimonenko, Vlada V., Dzijak, Rastislav, Venit, Tomáš, Hozák, Pavel

“…RNA polymerase I (Pol I) transcription is essential for the cell cycle, growth, and overall protein synthesis in eukaryotes. We found that phosphatidylinositol…”
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