Search Results - "Venero, José Luís"

APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases by Fernández-Calle, Rosalía, Konings, Sabine C, Frontiñán-Rubio, Javier, García-Revilla, Juan, Camprubí-Ferrer, Lluís, Svensson, Martina, Martinson, Isak, Boza-Serrano, Antonio, Venero, José Luís, Nielsen, Henrietta M, Gouras, Gunnar K, Deierborg, Tomas

“…ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of…”
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Chronic stress as a risk factor for Alzheimer's disease by Machado, Alberto, Herrera, Antonio J, de Pablos, Rocío M, Espinosa-Oliva, Ana María, Sarmiento, Manuel, Ayala, Antonio, Venero, José Luis, Santiago, Martiniano, Villarán, Ruth F, Delgado-Cortés, María José, Argüelles, Sandro, Cano, Josefina

“…This review aims to point out that chronic stress is able to accelerate the appearance of Alzheimer's disease (AD), proposing the former as a risk factor for…”
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The Ubiquitin Proteasome System in Neuromuscular Disorders: Moving Beyond Movement by Bachiller, Sara, Alonso-Bellido, Isabel M, Real, Luis Miguel, Pérez-Villegas, Eva María, Venero, José Luis, Deierborg, Tomas, Armengol, José Ángel, Ruiz, Rocío

“…Neuromuscular disorders (NMDs) affect 1 in 3000 people worldwide. There are more than 150 different types of NMDs, where the common feature is the loss of…”
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Gal3 Plays a Deleterious Role in a Mouse Model of Endotoxemia by Fernández-Martín, Juan Carlos, Espinosa-Oliva, Ana María, García-Domínguez, Irene, Rosado-Sánchez, Isaac, Pacheco, Yolanda M, Moyano, Rosario, Monterde, José G, Venero, José Luis, de Pablos, Rocío M

“…Lipopolysaccharide (LPS)-induced endotoxemia induces an acute systemic inflammatory response that mimics some important features of sepsis, the disease with…”
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Dopaminergic neurons lacking Caspase-3 avoid apoptosis but undergo necrosis after MPTP treatment inducing a Galectin-3-dependent selective microglial phagocytic response by García-Revilla, Juan, Ruiz, Rocío, Espinosa-Oliva, Ana M., Santiago, Marti, García-Domínguez, Irene, Camprubí-Ferrer, Lluís, Bachiller, Sara, Deierborg, Tomas, Joseph, Bertrand, de Pablos, Rocío M., Rodríguez-Gómez, José A., Venero, José Luis

“…Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the Substantia nigra pars compacta…”
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Galectin-3 shapes toxic alpha-synuclein strains in Parkinson’s disease by García-Revilla, Juan, Boza-Serrano, Antonio, Jin, Yiyun, Vadukul, Devkee M., Soldán-Hidalgo, Jesús, Camprubí-Ferrer, Lluís, García-Cruzado, Marta, Martinsson, Isak, Klementieva, Oxana, Ruiz, Rocío, Aprile, Francesco A., Deierborg, Tomas, Venero, José Luis

“…Parkinson’s Disease (PD) is a neurodegenerative and progressive disorder characterised by intracytoplasmic inclusions called Lewy bodies (LB) and degeneration…”
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Galectin-3 depletion tames pro-tumoural microglia and restrains cancer cells growth by Rivera-Ramos, Alberto, Cruz-Hernández, Luis, Talaverón, Rocío, Sánchez-Montero, María Teresa, García-Revilla, Juan, Mulero-Acevedo, Marta, Deierborg, Tomas, Venero, José Luis, Sarmiento Soto, Manuel

“…Galectin-3 (Gal-3) is a multifunctional protein that plays a pivotal role in the initiation and progression of various central nervous system diseases,…”
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Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation by Burguillos, Miguel Angel, Svensson, Martina, Schulte, Tim, Boza-Serrano, Antonio, Garcia-Quintanilla, Albert, Kavanagh, Edel, Santiago, Martiniano, Viceconte, Nikenza, Oliva-Martin, Maria Jose, Osman, Ahmed Mohamed, Salomonsson, Emma, Amar, Lahouari, Persson, Annette, Blomgren, Klas, Achour, Adnane, Englund, Elisabet, Leffler, Hakon, Venero, Jose Luis, Joseph, Bertrand, Deierborg, Tomas

“…Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory diseases. Although the role of…”
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Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration by Yip, Ping Kei, Carrillo-Jimenez, Alejandro, King, Paul, Vilalta, Anna, Nomura, Koji, Chau, Chi Cheng, Egerton, Alexander Michael Scott, Liu, Zhuo-Hao, Shetty, Ashray Jayaram, Tremoleda, Jordi L., Davies, Meirion, Deierborg, Tomas, Priestley, John V., Brown, Guy Charles, Michael-Titus, Adina Teodora, Venero, Jose Luis, Burguillos, Miguel Angel

“…Traumatic brain injury (TBI) is currently a major cause of morbidity and poor quality of life in Western society, with an estimate of 2.5 million people…”
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Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors by Hajji, Nabil, Garcia-Revilla, Juan, Soto, Manuel Sarmiento, Perryman, Richard, Symington, Jake, Quarles, Chad C, Healey, Deborah R, Guo, Yijie, Orta-Vázquez, Manuel Luis, Mateos-Cordero, Santiago, Shah, Khalid, Bomalaski, John, Anichini, Giulio, Tzakos, Andreas G, Crook, Timothy, O'Neill, Kevin, Scheck, Adrienne C, Venero, Jose Luis, Syed, Nelofer

“…New approaches for the management of glioblastoma (GBM) are an urgent and unmet clinical need. Here, we illustrate that the efficacy of radiotherapy for GBM is…”
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GALECTIN-3 REDUCES AMYLOID BETA PLAQUE AND ASSOCIATED DYSTROPHIES ON APP MICE by Hidalgo, Jesús Soldán, Boza-Serrano, Antonio, Vitorica, Javier, Venero, José Luis

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AGED MICROGLIA PROMOTE PRO-INFLAMMATORY MICROENVIRONMENT AND TUMOUR GROWTH ARREST by Rivera, Alberto, Sarmiento, Manuel, Venero, José Luis, Cruz, Luis, Sánchez, Maria Teresa

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HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System by Bachiller, Sara, Roca-Ceballos, María Angustias, García-Domínguez, Irene, Pérez-Villegas, Eva María, Martos-Carmona, David, Pérez-Castro, Miguel Ángel, Real, Luis Miguel, Rosa, José Luis, Tabares, Lucía, Venero, José Luis, Armengol, José Ángel, Carrión, Ángel Manuel, Ruiz, Rocío

“…A missense mutation in HERC1 provokes loss of cerebellar Purkinje cells, tremor, and unstable gait in tambaleante ( tbl ) mice. Recently, we have shown that…”
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GALECTIN-3 SHAPES TOXIC ALPHA-SYNUCLEIN AGGREGATES IN PARKINSON´S DISEASE by Garcia-Revilla, Juan, Boza-Serrano, Antonio, Yin, Yiyun, Vadukul, Devkee, Hidalgo, Jesús Soldán, Camprubí-Ferrer, Lluís, Cruzado, Marta Garcia, Martinsson, Isak, Klementieva, Oxana, Ruiz, Rocío, Aprile, Francesco, Deierborg, Tomas, Venero, José Luis

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Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation by Carrillo-Jimenez, Alejandro, Puigdellívol, Mar, Vilalta, Anna, Venero, Jose Luis, Brown, Guy Charles, StGeorge-Hyslop, Peter, Burguillos, Miguel Angel

“…Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, including Alzheimer's disease (AD)…”
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Galectin-3 Deletion Reduces LPS and Acute Colitis-Induced Pro-Inflammatory Microglial Activation in the Ventral Mesencephalon by Espinosa-Oliva, Ana M., García-Miranda, Pablo, Alonso-Bellido, Isabel María, Carvajal, Ana E., González-Rodríguez, Melania, Carrillo-Jiménez, Alejandro, Temblador, Arturo J., Felices-Navarro, Manuel, García-Domínguez, Irene, Roca-Ceballos, María Angustias, Vázquez-Carretero, María D., García-Revilla, Juan, Santiago, Marti, Peral, María J., Venero, José Luis, de Pablos, Rocío M.

“…Parkinson’s disease is a highly prevalent neurological disorder for which there is currently no cure. Therefore, the knowledge of risk factors as well as the…”
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HERC1 IS NECESSARY FOR AUTOPHAGY PROCESSES AND FOR THE MAINTENANCE AND HOMEOSTASIS OF VESICLES IN THE NEUROMUSCULAR JUNCTION, BUT NOT FOR THE PROTEASOMAL ACTIVITY by Hernandez, Francisco, Perez-Castro, Miguel Angel, Alonso-Bellido, Isabel Maria, Letrán-Sánchez, María De Los Santos, Perez-Villegas, Eva Maria, Vitalle, Joana, Real, Luis Miguel, Ruiz-Mateos, Ezequiel, Venero, José Luis, Tabares, Lucia, Rodríguez, Ángel Carrión, Armengol, José Ángel, Bachiller, Sara, Ruiz, Rocío

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Erratum: PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity by Dabrowska, Aleksandra, Venero, Jose Luis, Iwasawa, Ryota, Hankir, Mohammed-Khair, Rahman, Sunniyat, Boobis, Alan, Hajji, Nabil

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“Lucre - Huacarpay”: humedal mesoandino by Venero Gonzales, José Luis

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Magnetofection as a new tool to study microglia biology by Venero, Jose, Burguillos, Miguel

“…Microglia are the resident macrophages of the brain, originally described by Pío del Río-Hortega (a student of Santiago Ramon y Cajal) in a series of studies…”
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