Search Results - "Vence, L."

Lack Of Diversity In Genomic Databases Is A Barrier To Translating Precision Medicine Research Into Practice by Landry, Latrice G, Ali, Nadya, Williams, David R, Rehm, Heidi L, Bonham, Vence L

“…Precision medicine is predicted to revolutionize the clinical practice of medicine, in part by using molecular biomarkers to assess patients' risk, prognosis,…”
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Examining How Race, Ethnicity, and Ancestry Data Are Used in Biomedical Research by Bonham, Vence L, Green, Eric D, Pérez-Stable, Eliseo J

“…The complexities of social identity and genetic ancestry have led to confusion and consternation related to the use and interpretation of race, ethnicity, and…”
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The genomics workforce must become more diverse: a strategic imperative by Bonham, Vence L., Green, Eric D.

“…The National Human Genome Research Institute (NHGRI) recently published a new strategic vision for the future of human genomics, the product of an extensive,…”
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Leg ulcers are indicators of systemic dysfunction in individuals with sickle cell disease by Jackson, Tiffany A., Buscetta, Ashley J., Ramirez, Hasmin C., Bonham, Vence L., Minniti, Caterina P.

“…Leg ulcers in individuals living with Sickle Cell Disease are evidence of systemic dysfunction. Data from a U.S. study link leg ulcers to wider pulse pressure…”
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Prioritizing diversity in human genomics research by Hindorff, Lucia A., Bonham, Vence L., Brody, Lawrence C., Ginoza, Margaret E. C., Hutter, Carolyn M., Manolio, Teri A., Green, Eric D.

“…Key Points Knowledge of how genomic variants vary by population increases our ability to understand genomic contributions to health and disease and to apply…”
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Will Precision Medicine Move Us beyond Race? by Bonham, Vence L, Callier, Shawneequa L, Royal, Charmaine D

“…Although self-identified race may correlate with geographical ancestry, it does not predict an individual patient's genotype or drug response. Precision…”
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Evolving use of ancestry, ethnicity, and race in genetics research-A survey spanning seven decades by Byeon, Yen Ji Julia, Islamaj, Rezarta, Yeganova, Lana, Wilbur, W John, Lu, Zhiyong, Brody, Lawrence C, Bonham, Vence L

“…To inform continuous and rigorous reflection about the description of human populations in genomics research, this study investigates the historical and…”
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Health Disparities and the Microbiome by Findley, Keisha, Williams, David R, Grice, Elizabeth A, Bonham, Vence L

“…An individual's microbiome is likely to be an important contributor to certain health disparity diseases and conditions. We present a framework to study the…”
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Strategic vision for improving human health at The Forefront of Genomics by Green, Eric D., Gunter, Chris, Biesecker, Leslie G., Di Francesco, Valentina, Easter, Carla L., Feingold, Elise A., Felsenfeld, Adam L., Kaufman, David J., Ostrander, Elaine A., Pavan, William J., Phillippy, Adam M., Wise, Anastasia L., Dayal, Jyoti Gupta, Kish, Britny J., Mandich, Allison, Wellington, Christopher R., Wetterstrand, Kris A., Bates, Sarah A., Leja, Darryl, Vasquez, Susan, Gahl, William A., Graham, Bettie J., Kastner, Daniel L., Liu, Paul, Rodriguez, Laura Lyman, Solomon, Benjamin D., Bonham, Vence L., Brody, Lawrence C., Hutter, Carolyn M., Manolio, Teri A.

“…Starting with the launch of the Human Genome Project three decades ago, and continuing after its completion in 2003, genomics has progressively come to have a…”
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Equitable delivery of expanded genetic technologies: Considerations for prenatal and reproductive care by Adams, April D., Jumah, Naana, Okun, Nanette, Bonham, Vence L.

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A CRISPR focus on attitudes and beliefs toward somatic genome editing from stakeholders within the sickle cell disease community by Persaud, Anitra, Desine, Stacy, Blizinsky, Katherine, Bonham, Vence L.

“…Purpose Genome editing holds both tremendous therapeutic promise and significant potential risk. Sickle cell disease (SCD), the most commonly inherited blood…”
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Race-Based Care and Beliefs Regarding the Etiology of Racial Differences in Health Outcomes by Okah, Ebiere, Cronholm, Peter F., Crow, Brendan, Persaud, Anitra, Westby, Andrea, Bonham, Vence L.

“…Physicians’ perspectives regarding the etiology of racial health differences may be associated with their use of race in clinical practice (race-based…”
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Defining and Achieving Health Equity in Genomic Medicine by Jooma, Sonya, Hahn, Michael J., Hindorff, Lucia A., Bonham, Vence L.

“…The potential of genomics to improve health comes with the peril that the benefits will not be equitably available to all populations. Existing health…”
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The clinical imperative for inclusivity: Race, ethnicity, and ancestry (REA) in genomics by Popejoy, Alice B., Ritter, Deborah I., Crooks, Kristy, Currey, Erin, Fullerton, Stephanie M., Hindorff, Lucia A., Koenig, Barbara, Ramos, Erin M., Sorokin, Elena P., Wand, Hannah, Wright, Mathew W., Zou, James, Gignoux, Christopher R., Bonham, Vence L., Plon, Sharon E., Bustamante, Carlos D.

“…The Clinical Genome Resource (ClinGen) Ancestry and Diversity Working Group highlights the need to develop guidance on race, ethnicity, and ancestry (REA) data…”
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The Role of the Health Care Provider in Building Trust Between Patients and Precision Medicine Research Programs by Persaud, Anitra, Bonham, Vence L.

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Clinical Outcomes Associated With Sickle Cell Trait: A Systematic Review by Naik, Rakhi P, Smith-Whitley, Kim, Hassell, Kathryn L, Umeh, Nkeiruka I, de Montalembert, Mariane, Sahota, Puneet, Haywood, Jr, Carlton, Jenkins, Jean, Lloyd-Puryear, Michele A, Joiner, Clinton H, Bonham, Vence L, Kato, Gregory J

“…Although sickle cell trait (SCT) is largely a benign carrier state, it may increase risk for certain clinical outcomes. To evaluate associations between SCT…”
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Is there a way to reduce the inequity in variant interpretation on the basis of ancestry? by Appelbaum, Paul S., Burke, Wylie, Parens, Erik, Zeevi, David A., Arbour, Laura, Garrison, Nanibaa’ A., Bonham, Vence L., Chung, Wendy K.

“…The underrepresentation of non-European ancestry groups in current genomic databases complicates interpretation of their genetic test results, yielding a much…”
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Emergency Department Utilization for Patients Living With Sickle Cell Disease: Psychosocial Predictors of Health Care Behaviors by Abdallah, Khadijah, Buscetta, Ashley, Cooper, Kayla, Byeon, Julia, Crouch, Andrew, Pink, Sabrina, Minniti, Caterina, Bonham, Vence L.

“…Individuals living with sickle cell disease (SCD) often require urgent care; however, some patients hesitate to present to the emergency department (ED), which…”
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Social support networks of adults with sickle cell disease by Desine, Stacy, Eskin, Lena, Bonham, Vence L., Koehly, Laura M.

“…Sickle cell disease (SCD) can cause both physical and psychological complications, such as severe pain and depression. These effects often necessitate social…”
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Views of adults living with sickle cell disease on the theoretical return of secondary genomic findings by Floyd, K Jameson, Wossenseged, Faeben, Buscetta, Ashley J, Fasaye, Grace-Ann, Bonham, Vence L

“…Although the body of research investigating research participants' opinions on the return of actionable secondary genomic findings grows, there has been…”
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