Search Results - "Velleca, Mark"

Multiplexed protein profiling on microarrays by rolling-circle amplification by Kingsmore, Stephen F, Schweitzer, Barry, Tchernev, Velizar T, Grimwade, Brian, Zhou, Zhimin, Roberts, Scott, Shao, Weiping, Fu, Qin, Shu, Quiping, Velleca, Mark, Christiansen, Jason, Laroche, Isabelle, Wang, Minjuan

“…Fluorescent-sandwich immunoassays on microarrays hold appeal for proteomics studies, because equipment and antibodies are readily available, and assays are…”
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New FDA breakthrough-drug category--implications for patients by Velleca, Mark

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Large-Scale Culture and Selective Maturation of Human Langerhans Cells from Granulocyte Colony-Stimulating Factor-Mobilized CD34+ Progenitors by Gatti, Evelina, Velleca, Mark A, Biedermann, Barbara C, Ma, Weilie, Unternaehrer, Juli, Ebersold, Melanie W, Medzhitov, Ruslan, Pober, Jordan S, Mellman, Ira

“…Dendritic cells (DCs) play a critical role as APCs in the induction of the primary immune response. Their capacity for Ag processing and presentation is…”
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Genetically engineered mouse models for drug discovery: new chemical genetic approaches by Heck, Susanne, Qian, Xiaobing, Velleca, Mark

“…While standard transgenic and knockout mouse technologies have provided a wealth of information for target selection and validation, there have been great…”
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Ex vivo evaluation of PBMNCs collected with a new cell separator by Snyder, Edward L., O'Donnell, Lynn, Dengler, Thomas J., Pomper, Gregory J., Velleca, Mark A., Dincecco, Dorothy M., Baril, Laurene L., Min, Kyungyoon, Gudino, Maria D., Bender, Jeffrey R.

“…BACKGROUND: This study reports on an evaluation of the ability of a cell separator (Amicus, Baxter Healthcare) and the integral MNC computer software program…”
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Supporting US public health experts by Cohen, Ron, Francois, Cedric, Crowley, John, Hastings, Paul, King, Rachel, Love, Ted W., Maraganore, John, McMurry-Heath, Michelle, Levin, Jeremy

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Author Correction: Supporting US public health experts by Cohen, Ron, Francois, Cedric, Crowley, John, Hastings, Paul, King, Rachel, Love, Ted W., Maraganore, John, McMurry-Heath, Michelle, Levin, Jeremy

“…A Correction to this paper has been published: https://doi.org/10.1038/s41587-020-00792-5…”
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Novel chemical genetic approaches to the discovery of signal transduction inhibitors by Shokat, Kevan, Velleca, Mark

“…Concurrent advances in both high-throughput chemistry and genomics have given rise to the field of chemical genetics as a discipline for elucidating and…”
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New FDA Breakthrough-Drug Category — Implications for Patients by McClellan, Mark, Sigal, Ellen, Murray, Barbara E, Velleca, Mark, Ricart, Alejandro D, Darrow, Jonathan J, Avorn, Jerry, Kesselheim, Aaron S

“…To the Editor: Darrow et al. (March 27 issue) 1 present an incomplete and misleading review of the Food and Drug Administration (FDA) programs that are…”
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Abstract 3286: Oral bioavailability, permeability, CYP profiling, identification of major metabolites, tissue distribution and excretion profile of a novel triple kinase inhibitor, JI-101 in rats by Gurav, Sandip Dhondiram, Gilibili, Ravindranath Reddy, Jeniffer, Sherine, Zainuddin, Mohd, Giri, Sanjeev, Govindrajan, Raman, Velleca, Mark, Nuggehally, Srinivas, Mullangi, Ramesh

“…Abstract Objectives JI-101 is a novel orally active kinase inhibitor has shown potent in vitro and in vivo anticancer activity against a variety of cancer cell…”
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Abstract B11: Preclinical and preliminary phase 1 trial results of JI-101: A novel, oral tyrosine kinase inhibitor that selectively targets VEGFR2, EphB4, and PDGFR by Velleca, Mark, Brittelli, David, Elkin, Lisa, Klein, Udo, Mitchell, Scott, Qian, Dapeng, Qian, Xiaobing, Srinivasa, Sreesha, Stephan, Thomas, Govindarajan, Raman, Stern, Warren, Gordon, Michael, Sharma, Sunil, Miller, Linda

“…Abstract Introduction: JI-101 is a highly selective and potent angiogenesis inhibitor with unique EphB4 activity that distinguishes it from other agents in…”
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Abstract 17: Preclinical and phase 1 trial results of JI-101, a novel, oral tyrosine kinase inhibitor that selectively targets VEGFR2, EphB4, and PDGFRβ by Velleca, Mark, Miller, Linda, Sharma, Sunil, Gordon, Michael, Brittelli, David, Elkin, Lisa, Govindarajan, Raman, Klein, Udo, Mitchell, Scott, N, Nandhagopal, Qian, Dapeng, Qian, Xiaobing, Stephen, Thomas, Srinivasa, Sreesha, Stern, Warren

“…Abstract Introduction JI-101 is a highly selective and potent angiogenesis inhibitor with unique EphB4 activity that distinguishes it from other agents in…”
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Type 2X-Myosin Heavy Chain Is Coded by a Muscle Fiber Type-Specific and Developmentally Regulated Gene by DeNardi, Costanza, Ausoni, Simonetta, Moretti, Paolo, Gorza, Luisa, Velleca, Mark, Buckingham, Margaret, Schiaffino, Stefano

“…We have previously reported the identification of a distinct myosin heavy chain (MyHC) isoform in a major subpopulation of rat skeletal muscle fibers, referred…”
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Molecular Cloning and Tissue Distribution of PHAS-I, an Intracellular Target for Insulin and Growth Factors by Hu, Chaobin, Pang, Suhong, Kong, Xianming, Velleca, Mark, Lawrence, John C.

“…Although the actions of insulin and a number of growth factors that signal via protein-tyrosine kinase receptors are believed to involve increased…”
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Chemical genetic transcriptional fingerprinting for selectivity profiling of kinase inhibitors by Jiang, Shan, DiPaolo, Julie, Currie, Kevin, Alderucci, Scott, Ramamurthy, Arun, Peppers, Johnny, Qian, Xiaobing, Qian, Dapeng, Awad, Tarif, Velleca, Mark, Whitney, J Andrew

“…The importance of protein kinases as a major class of drug targets across multiple diseases has generated a critical need for technologies that enable the…”
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A novel synapse-associated noncoding RNA by Velleca, M A, Wallace, M C, Merlie, J P

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Molecular Cloning and Sequence Analysis of the Chlamydomonas Gene Coding for Radial Spoke Protein 3: Flagellar Mutation pf-14 Is an Ochre Allele by Williams, Benjamin D., Velleca, Mark A., Curry, Alice M., Rosenbaum, Joel L.

“…Chlamydomonas reinhardtii flagellar motility mutant pf-14 fails to assemble radial spokes because of a deficiency for assembly-competent radial spoke protein…”
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Subtractive cloning of a novel synapse-specific noncoding RNA by Velleca, Mark Albert

“…To understand the mechanism of transynaptic gene regulation at the neuromuscular junction, I have used subtractive hybridization to identify candidate synaptic…”
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A Novel Synapse-Associated Noncoding RNA by Velleca, Mark A., Wallace, Mia C., Merlie, John P.

“…Synaptic nuclei of innervated muscle transcribe acetylcholine receptor (AChR) genes at a much higher level than extrasynaptic nuclei. To isolate candidate…”
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